Characterization of a recombinant Yersinia enterocolitica lipoprotein; implications for its role in autoimmune response against thyrotropin receptor

Autoimmunity

Volumn 37, Issue 6-7, 2004, Pages 515-520

  Gangi, Eryn ^a   Kapatral, Vinayak ^a,b   El Idrissi, Mohammed El Azami ^a,c   Martinez, Osvaldo ^a   Prabhakar, Bellur S ^a  

^a UNIVERSITY OF ILLINOIS   (United States)

^b Integrated Genomics   (United States)

^c INSTITUT PASTEUR   (France)

Author keywords

Autoimmunity; Graves' disease; Lipoprotein; Thyrotropin receptor; Yersinia enterocolitica

Indexed keywords

B7 ANTIGEN; INTERLEUKIN 6; LIPOPROTEIN; RECOMBINANT PROTEIN; THYROTROPIN RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN EXPRESSION; ARTICLE; AUTOIMMUNITY; CELL CULTURE; CELL SELECTION; CONTROLLED STUDY; CROSS REACTION; CYTOKINE RELEASE; FEMALE; FLUORESCENCE ACTIVATED CELL SORTING; GENE EXPRESSION; IMMUNE RESPONSE; IMMUNOMODULATION; LYMPHOCYTE PROLIFERATION; MITOGENICITY; MOLECULAR CLONING; MOUSE; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN PURIFICATION; SPLEEN CELL; WESTERN BLOTTING; YERSINIA ENTEROCOLITICA;

ANIMALS; ANTIGENS, CD; ANTIGENS, CD86; AUTOIMMUNITY; B-LYMPHOCYTES; INTERLEUKIN-6; LIPOPROTEINS; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED CBA; RECEPTORS, THYROTROPIN; UP-REGULATION; YERSINIA ENTEROCOLITICA;

EID: 12344282706     PISSN: 08916934     EISSN: None     Source Type: Journal    
DOI: 10.1080/08916930410001728074     Document Type: Article

References (20)

1. Oldstone, M.B. (1998) "Molecular mimicry and immune-mediated diseases", FASEB J. 12(13), 1255-1265.
2. Tomer, Y. and Davies, T.F. (1993) "Infection, thyroid disease, and autoimmunity", Endocr. Rev. 14(1), 107-120.
3. Bech, K. (1990) "Yersinia enterocolitica and thyroid autoimmunity", Autoimmunity 7(4), 291-294.
4. Shenkman, L. and Bottone, E.J. (1976) "Antibodies to Yersinia enterocolitica in thyroid disease", Ann. Intern. Med. 85(6), 735-739.
5. Wenzel, B.E., Heesemann, J., Wenzel, K.W. and Scriba, P.C. (1988) "Patients with autoimmune thyroid diseases have antibodies to plasmid encoded proteins of enteropathogenic Yersinia", J. Endocrinol. Investig. 11(2), 139-140.
6. Prabhakar, B.S., Bahn, R.S. and Smith, T.J. (2003) "Current perspective on the pathogenesis of Graves' disease and opthalmopathy", Endocr. Rev. 24, 802-835.
7. Weiss, M., Ingbar, S.H., Winblad, S. and Kasper, D.L. (1983) "Demonstration of a saturable binding site for thyrotropin in Yersinia enterocolitica", Science 18(219 (4590)), 1331-1333.
8. Heyma, P., Harrison, L.C. and Robins-Browne, R. (1986) "Thyrotrophin (TSH) binding sites on Yersinia enterocolitica recognized by immunoglobulins from humans with Graves' disease", Clin. Exp. Immunol. 64(2), 249-254.
9. Zhang, H., Kant, I., Niesel, D.W., Seetharamaiah, G.S., Peterson, J.W., Prabhakar, B.S. and Klimpel, G.R. (1997) " Lipoprotein from Yersinia enterocolitica contains epitopes that cross-react with the human thyrotropin receptor.", J. Immunol. 158(4), 1976-1983.
10. Zhang, H., Kaur, I., Niesel, D.W., Seetharamaiah, G.S., Peterson, J.W., Justement, L.B., Prabhakar, B.S. and Klimpel, G.R. (1996) "Yersinia enterocolitica envelope proteins that are crossreactive with the thyrotropin receptor (TSHR) also have B-cell mitogenic activity", J. Autoimmun. 9(4), 509-516.
11. Luo, G., Seetharamaiah, G.S., Niesel, D.W., Zhang, H., Peterson, J.W., Prabhakar, B.S. and Klimpel, G.R. (1994) " Purification and characterization of Yersinia enterocolitica envelope proteins which induce antibodies that react with human thyrotropin receptor", J. Immunol. 152(5), 2555-2561.
12. Appleman, L.J. and Boussiotis, V.A. (2003) "T cell anergy and costimulation", Immunol. Rev. 192, 161-180.
13. Al-Bader, T., Christodoulides, M., Heckels, J.E., Holloway, J., Semper, A.E. and Friedmann, P.S. (2003) "Activation of human dendritic cells is modulated by components of the outer membranes of Neisseria meningitidis", Infect. Immun. 71 (10), 5590-5597.
14. Wenzel, B.E., Heesemann, J., Heufelder, A., Franke, T.F., Grammerstorf, S., Stemerowicz, R. and Hopf, U. (1991) " Entero-pathogenic Yersinia enterocolitica and organ-specific autoimmune diseases in man", Contrib. Microbiol. Immunol. 12, 80-88.
15. Silva, E.E., Ramos, O.P., Bauab, T.M., Falcao, D.P. and de Medeiros, B.M. (2003) "Yersinia enterocolitica O:3 isolated from patients with or without reactive arthritis induces polyclonal activation of B cells and autoantibody production in vivo", Autoimmunity 36(5), 261-268.
16. Crespo Ade, M., Falcao, D.P., de, A.P. and de, M.B. (2002) "Effects of Yersinia enterocolitica O:3 derivatives on B lymphocyte activation in vivo", Microbiol. Immunol. 46(2), 95-100.
17. Pasare, C. and Medzhitov, R. (2003) "Toll pathway-dependent blockade of CD4+ CD25+ T cell-mediated suppression by dendritic cells", Science 299(5609), 1033-1036.
18. Shevach, E.M. (2000) "Regulatory T cells in autoimmunity", Annu. Rev. Immunol. 18, 423-449.
19. Aliprantis, A.O., Yang, R.B., Mark, M.R., Suggett, S., Devaux, B., Radolf, J.D., Klimpel, G.R., Godowski, P. and Zychlinsky, A. (1999) "Cell activation and apoptosis by bacterial lipoproteins through toll-like receptor-2", Science 285 (5428), 736-739.
20. Akkaraju, S., Canaan, K. and Goodnow, C.C. (1997) "Self-reactive B cells are not eliminated or inactivated by autoantigen expressed on thyroid epithelial cells", J. Exp. Med. 186 12), 2005-2012.