Expression of the mouse WNK1 gene in correlation with ganglioside GD3 and functional analysis of the mouse WNK1 promoter

Gene

Volumn 344, Issue , 2005, Pages 233-239

  Zeng, Guichao ^a   Gao, Luoyi ^a   Xia, Tian ^a   Gu, Yihua ^a   Yu, Robert K ^a  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

Author keywords

Ganglioside; Gene expression; Promoter; Protein kinase; Transcriptional regulation

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN; CELLULAR NUCLEIC ACID BINDING PROTEIN; GANGLIOSIDE GD3; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NUCLEIC ACID BINDING PROTEIN; OCTAMER TRANSCRIPTION FACTOR 1; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP 2; TRANSCRIPTION FACTOR EST 1; TRANSCRIPTION FACTOR SP1; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING SITE; BREAST CELL; CODON; CONSENSUS; CONTROLLED STUDY; CORRELATION ANALYSIS; DNA FLANKING REGION; FRAGMENTATION REACTION; GENE ACTIVITY; GENE EXPRESSION; GENE IDENTIFICATION; GENETIC ANALYSIS; GENETIC TRANSFECTION; MOLECULAR CLONING; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; TATA BOX; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION;

5' FLANKING REGION; ANIMALS; BINDING SITES; BRAIN; CELL LINE, TUMOR; GANGLIOSIDES; GENE EXPRESSION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE EXPRESSION REGULATION, NEOPLASTIC; LUCIFERASES; MICE; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS (GENETICS); PROTEIN-SERINE-THREONINE KINASES; RECOMBINANT FUSION PROTEINS; SIALYLTRANSFERASES; TRANSCRIPTION FACTORS; TRANSCRIPTION INITIATION SITE; TRANSCRIPTION, GENETIC; TRANSFECTION;

EID: 12344264912     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.gene.2004.10.003     Document Type: Article

References (27)

1. J.M. Achard, D.G. Warnock, S. Disse-Nicodeme, B. Fiquet-Kempf, P. Corvol, A. Fournier, and X. Jeunemaitre Familial hyperkalemic hypertension: phenotypic analysis in a large family with the WNK1 deletion mutation Am. J. Med. 114 2003 495 498
2. L.Q. Benson, M.R. Coon, L.M. Krueger, G.C. Han, A.A. Sarnaik, and D.S. Wechsler Expression of MXI1, a Myc antagonist, is regulated by Sp1 and AP2 J. Biol. Chem. 274 1999 28794 28802
3. S. Birkle, G. Zeng, L. Gao, R.K. Yu, and J. Aubry Role of tumor-associated gangliosides in cancer progression Biochimie 85 2003 455 463
4. M. Brandeis, D. Frank, I. Keshet, Z. Siegfried, M. Mendelsohn, A. Nemes, V. Temper, A. Razin, and H. Cedar Sp1 elements protect a CpG island from de novo methylation Nature 371 1994 435 438
5. L. Chang, and M. Karin Mammalian MAP kinase signalling cascades Nature 410 2001 37 40
6. --transporting epithelia Proc. Natl. Acad. Sci. U. S. A. 100 2003 663 866
7. C. Delaloy, J. Lu, A.M. Houot, S. Disse-Nicodeme, J.M. Gasc, P. Corvol, and X. Jeunemaitre Multiple promoters in the WNK1 gene: one controls expression of a kidney-specific kinase-defective isoform Mol. Cell. Biol. 23 2003 9208 9221
8. S. Hakomori Tumor malignancy defined by aberrant glycosylation and sphingo(glyco)lipid metabolism Cancer Res. 56 1996 5309 5318
9. S. Hakomori Glycosylation defining cancer malignancy: new wine in an old bottle Proc. Natl. Acad. Sci. U. S. A. 99 2002 10231 10233
10. T.A. Ince, and K.W. Scotto A conserved downstream element defines a new class of RNA polymerase II promoters J. Biol. Chem. 270 1995 30249 30252
11. Y.X. Li, J. Papkoff, and N.H. Sarkar Antisense downregulation of a mouse mammary tumor virus activated protooncogene in mouse mammary tumor cells reverses the malignant phenotype Virology 255 1999 138 149
12. M. Marin, A. Karis, P. Visser, F. Grosveld, and S. Philipsen Transcription factor Sp1 is essential for early embryonic development but dispensable for cell growth and differentiation Cell 89 1997 619 628
13. T.M. Moore, R. Garg, C. Johnson, M.J. Coptcoat, A.J. Ridley, and J.D. Morris PSK, a novel STE20-like kinase derived from prostatic carcinoma that activates the c-Jun N-terminal kinase mitogen-activated protein kinase pathway and regulates actin cytoskeletal organization J. Biol. Chem. 275 2000 4311 4322
14. M. O'Reilly, E. Marshall, H.J. Speirs, and R.W. Brown WNK1, a gene within a novel blood pressure control pathway, tissue-specifically generates radically different isoforms with and without a kinase domain J. Am. Soc. Nephrol. 14 2003 2447 2456
15. H. Schorle, P. Meier, M. Buchert, R. Jaenisch, and P.J. Mitchell Transcription factor AP-2 essential for cranial closure and craniofacial development Nature 381 1996 235 238
16. F. Verissimo, and P. Jordan WNK kinases, a novel protein kinase subfamily in multi-cellular organisms Oncogene 20 2001 5562 5569
17. F.H. Wilson Human hypertension caused by mutations in WNK kinases Science 293 2001 1107 1112
18. F.H. Wilson, K.T. Kahle, E. Sabath, M.D. Lalioti, A.K. Rapson, R.S. Hoover, S.C. Hebert, G. Gamba, and R.P. Lifton Molecular pathogenesis of inherited hypertension with hyperkalemia: the Na-Cl cotransporter is inhibited by wild-type but not mutant WNK4 Proc. Natl. Acad. Sci. U. S. A. 100 2003 680 684
19. B. Xu, J.M. English, J.L. Wilsbacher, S. Stippec, E.J. Goldsmith, and M.H. Cobb WNK1, a novel mammalian serine/threonine protein kinase lacking the catalytic lysine in subdomain II J. Biol. Chem. 275 2000 16795 16801
20. B.E. Xu, S. Stippec, L. Lenertz, B.H. Lee, W. Zhang, Y.K. Lee, and M.H. Cobb WNK1 activates ERK5 by an MEKK2/3-dependent mechanism J. Biol. Chem. 279 2004 7826 7831
21. A. Yamamoto, M. Haraguchi, S. Yamashiro, S. Fukumoto, K. Furukawa, K. Takamiya, M. Atsuta, and H. Shiku Heterogeneity in the expression pattern of two ganglioside synthase genes during mouse brain development J. Neurochem. 66 1996 26 34
22. R.K. Yu Development regulation of ganglioside metabolism Prog. Brain Res. 101 1994 31 44
23. G. Zeng, J.R. Dave, and P.K. Chiang Induction of protooncogenes during 3-deazaadenosine-stimulated differentiation of 3T3-L1 fibroblasts to adipocytes: mimicry of insulin action Oncol. Res. 9 1997 205 211
24. G. Zeng, D.D. Li, L. Gao, S. Birkle, E. Bieberich, A. Tokuda, and R.K. Yu Alteration of ganglioside composition by stable transfection with antisense vectors against GD3-synthase gene expression Biochemistry 38 1999 8762 8769
25. G. Zeng, L. Gao, S. Birkle, and R.K. Yu Suppression of ganglioside GD3 expression in a rat F-11 tumor cell line reduces tumor growth, angiogenesis, and vascular endothelial growth factor production Cancer Res. 60 2000 6670 6676
26. G. Zeng, L. Gao, and R.K. Yu Reduced cell migration, tumor growth and experimental metastasis of rat F-11 cells whose expression of GD3-synthase is suppressed Int. J. Cancer 88 2000 53 57
27. G. Zeng, L. Gao, K. Suetake, R.M. Joshi, and R.K. Yu Variations in gene expression patterns correlated with phenotype of F-11 tumor cells whose expression of GD3-synthase is suppressed Cancer Lett. 178 2002 91 98