Inhibition of p38 mitogen-activated protein kinase ameliorates cytokine up-regulated shigatoxin-1 toxicity in human brain microvascular endothelial cells

Journal of Infectious Diseases

Volumn 191, Issue 3, 2005, Pages 461-471

  Stricklett, Peter K ^a   Hughes, Alisa K ^a   Kohan, Donald E ^a,b  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF UTAH HEALTH SCIENCES CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CERAMIDE DERIVATIVE; CERAMIDE GLUCOSYLTRANSFERASE; CYTOKINE; GALACTOSE ALPHA 1,4 GALACTOSE BETA 1,4 GLUCOSE CERAMIDE; LACTOSYLCERAMIDE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE C; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; VEROTOXIN 1; VEROTOXIN 2;

ARTICLE; BRAIN INJURY; CELL SURFACE; CONTROLLED STUDY; CYTOTOXICITY; ENDOTHELIUM CELL; ENZYME ACTIVITY; HEMOLYTIC UREMIC SYNDROME; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; UPREGULATION;

BRAIN; CELLS, CULTURED; ENDOTHELIAL CELLS; ENZYME INHIBITORS; GALACTOSYLTRANSFERASES; GLUCOSYLTRANSFERASES; HUMANS; IMIDAZOLES; MICROCIRCULATION; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PYRIDINES; SHIGA-LIKE TOXIN I; SIGNAL TRANSDUCTION; TRIHEXOSYLCERAMIDES; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 12344262734     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/427188     Document Type: Article

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