Ondansetron, a selective 5-HT3 antagonist, antagonizes methamphetamine-induced anorexia in mice

Pharmacological Research

Volumn 51, Issue 3, 2005, Pages 255-259

  Ginawi, O T ^a   Al Majed, A A ^a   Al Suwailem, A K ^a  

^a KING SAUD UNIVERSITY   (Saudi Arabia)

Author keywords

5 HT antagonists; Anorexia; Food intake; Methamphetamine; Methiothepin; Methysergide; Mianserin; NAN 190; Ondansetron

Indexed keywords

1 (2 METHOXYPHENYL) 4 (4 PHTHALIMIDOBUTYL)PIPERAZINE; METHAMPHETAMINE; METHYSERGIDE; METITEPINE; MIANSERIN; ONDANSETRON; SEROTONIN 3 ANTAGONIST; SEROTONIN ANTAGONIST; SEROTONIN RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANOREXIA; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG SCREENING; DRUG SELECTIVITY; FOOD INTAKE; LOW DRUG DOSE; MOUSE; NONHUMAN; PRIORITY JOURNAL; TIME;

ANIMALS; ANOREXIA; EATING; MALE; METHAMPHETAMINE; MICE; ONDANSETRON; RECEPTORS, SEROTONIN, 5-HT3; SEROTONIN ANTAGONISTS;

EID: 12344262523     PISSN: 10436618     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.phrs.2004.09.002     Document Type: Article

References (30)

1. J.E. Blundell Serotonin and appetite Neuropharmacology 23 1984 1537 1551
2. S. Garattini, T. Mennini, C. Bendotti, R. Invernizzi, and R. Samanin Neurochemical mechanism of action of drugs which modify feeding via the serotoninergic system Appetite 7 1986 15 38
3. J. Duhault, M. Boulanger, C. Voisin, C.H. Malen, and H. Schmitt Fenfluramine and 5-hydroxytryptamine: involvement of brain 5-hydroxytryptamine in the anorectic activity of fenfluramine Arzneim Forsch 25 1975 1758 1762
4. T. Silverstone, and E. Goodall Serotoninergic mechanisms in human feeding: the pharmacological evidence Appetite 7 1986 85 97
5. R. Samanin, T. Mennini, and S. Garattini Evidence that it is possible to cause anorexia by increasing release and/or directly stimulating postsynaptic serotonin receptors in the brain Prog Neuropsychopharmacol 4 1980 363 369
6. 1B agonists induce anorexia at postsynaptic site Eur J Pharmacol 141 1987 429 435
7. J.C. Halford, and J.E. Blundell Pharmacology of appetite suppression Prog Drug Res 54 2000 25 58
8. S.F. Leibowitz The role of serotonin in eating disorders Drugs 3 1990 33 48
9. S. Garattini, A. Bizzi, S. Caccia, T. Mennini, and R. Samanin Progress in assessing the role of serotonin in the control of food intake Clin Neuropharmacol 11 1988 S8 S33
10. A. Frazer, S. Maayani, and B.B. Wolfe Subtypes of receptors for serotonin Annu Rev Pharmacol Toxicol 30 1990 307 348
11. I. Van Wijngaarden, M. Tulp, and W. Soudijin The concept of selectivity in 5-HT receptor research Eur J Pharmacol 188 1990 301 312
12. J.E. Ahlskog Food intake and amphetamine anorexia after selective forebrain norepinephrine loss Brain Res 82 1974 211 240
13. S.F. Leibowitz, and L.L. Brown Histochemical and pharmacological analysis of catecholaminergic projection to the lateral hypothalamus in relation to feeding inhibition Brain Res 201 1980 315 321
14. R. Samanin Amphetamine and fenfluramine, two drugs for studies on food intake Int J Obes 2 1978 349 351
15. C.S. Aulakh, R.M. Cohen, J.L. Hill, D.L. Murphy, and J. Zohar Long term imipramine treatment enhances the locomotor and food intake suppressant effects of m-CPP in rats Br J Pharmacol 91 1987 747 752
16. G. Curzon, E.L. Gibson, and Oluyomi AO Appetite suppression by commonly used drugs depends on 5-HT receptors but not on 5-HT availability Trends Pharmacol Sci 18 1977 191 192
17. 1B receptors in the control of feeding in rats Life Sci 41 1987 635 642
18. C.T. Dourish, P.H. Hutson, and G. Curzon Characteristics of feeding induced by the serotonin agonist 8-hydroxy-2-(di-n-propylamino) tetralin (8-OH-DPAT). Brain Res 15 1985 377 384
19. 3H] imipramine binding and decreases beta-adrenergic receptor function Eur J Pharmacol 89 1983 111 117
20. A. Dekeyne, A. Gobert, A. Auclair, S. Girardon, and M.J. Millan Differential modulation of the efficiency in a food-rewarded differential reinforcement of low-rate 72-S schedule in rats by norepinephrine and serotonin reuptake inhibitors Psychopharmacology 162 2002 156 167
21. 1C receptors Am J Physiol 264 1993 62 64
22. A. Cerdan, M. Acosta, and T. Jolin Long term administration of Pizotifen to migraine patients: effects of oral glucose tolerance tests on insulin levels Headache 15 1976 125 128
23. 1A agonist 8-OH-DPAT in the rat Eur J Pharmacol 219 1992 105 112
24. 1A receptor antagonist NAN-190 on rat brain serotonergic transmission Eur J Pharmacol 204 1991 71 77
25. 1A receptors Eur J Pharmacol 150 1988 361 367
26. C.T. Dourish, P.H. Hutson, and G. Curzon Low doses of the putative serotonin agonist 8-hydroxy-2-(di-n-propylamino) tetralin (8-OH-DPAT) elicit feeding in the rat Psychopharmacology 86 1985 197 204
27. C.T. Dourish, P.H. Hutson, and G. Curzon Parachlorophenyl-alanine prevents feeding induced by the serotonin agonist 8-hydroxy-2-(di-n-propylamino) tetralin (8-OH-DPAT) Psychopharmacology 89 1986 467 471
28. P.J. Winsauer, J.F. Verrees, K.P. O' Halloran, M.A. Bixler, and P.C. Mole Effects of chlordiazepoxide, 8-OH-DPAT and ondansetron on radiation-induced decreases in food intake in rats J Pharmacol Exp Ther 270 1994 142 149
29. 3-receptor antagonist Br J Pharmacol 93 1988 985 993
30. S.A. Montgomery, and N. Fineberg Is there a relationship between serotonin receptor subtypes and selectivity of response in specific psychiatric illnesses? Br J Psychiatry 8 1989 63 69