A simple and sensitive LC/MS/MS assay for 7-ethyl-10-hydroxycamptothecin (SN-38) in mouse plasma and tissues: Application to pharmacokinetic study of liposome entrapped SN-38 (LE-SN38)

Journal of Pharmaceutical and Biomedical Analysis

Volumn 37, Issue 1, 2005, Pages 135-142

  Khan, Sumsullah ^a   Ahmad, Ateeq ^a   Guo, Wei ^a   Wang, Yue Fen ^a   Abu Qare, Aqel ^a   Ahmad, Imran ^a  

^a NeoPharm Inc   (United States)

Author keywords

Camptothecin; LC MS MS; Liposome; Mice; Pharmacokinetics; SN 38

Indexed keywords

7 ETHYL 10 HYDROXYCAMPTOTHECIN; ACETIC ACID; ACETONITRILE; CAMPTOTHECIN; LIPOSOME;

ACCURACY; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DILUTION; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG TISSUE LEVEL; FEMALE; INSTRUMENTATION; KIDNEY; LINEAR SYSTEM; LIQUID CHROMATOGRAPHY; LIVER; LUNG; MASS SPECTROMETER; MASS SPECTROMETRY; MOUSE; NONHUMAN; PRECIPITATION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SENSITIVITY AND SPECIFICITY; SPLEEN; STANDARD; TISSUE HOMOGENATE;

ANIMALS; CAMPTOTHECIN; CHROMATOGRAPHY, LIQUID; LIPOSOMES; MASS SPECTROMETRY; MICE; TISSUE DISTRIBUTION;

EID: 12344256836     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2004.09.053     Document Type: Article

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