The anti-dementia drug FK960 stimulates glial glutamate release via a PKA pathway

Molecular Brain Research

Volumn 109, Issue 1-2, 2002, Pages 63-68

  Tada, Hitoshi ^a   Uchino, Motoi ^a   Nagai, Kaoru ^a   Nomura, Tamotsu ^a   Kondoh, Takeshi ^b   Saito, Naoaki ^c   Yamamura, Takehira ^a   Yajima, Yukio ^a   Nishizaki, Tomoyuki ^a  

^a HYOGO COLLEGE OF MEDICINE   (Japan)

^b KOBE UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c KOBE UNIVERSITY   (Japan)

Author keywords

Astrocytes; FK960; GLT 1; Glutamate release; Glutamate transporter; Hippocampal neurotransmission; Knock out mouse

Indexed keywords

2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; BAFILOMYCIN A1; CALCIUM ION; CYCLIC AMP DEPENDENT PROTEIN KINASE; DIHYDROKAINIC ACID; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; FORSKOLIN; GLUTAMATE TRANSPORTER; GLUTAMIC ACID; N (2 AMINOETHYL) 5 ISOQUINOLINESULFONAMIDE; N (4 ACETYL 1 PIPERAZINYL) 4 FLUOROBENZAMIDE; NOOTROPIC AGENT;

AMINO ACID TRANSPORT; ANIMAL CELL; ARTICLE; ASTROCYTE; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; CALCIUM TRANSPORT; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; EMBRYO; GLIA CELL; HIPPOCAMPUS; MOUSE; NERVE CELL CULTURE; NEUROTRANSMISSION; NEUROTRANSMITTER RELEASE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT; STIMULATION;

ANIMALS; ASTROCYTES; BENZAMIDES; CALCIUM; CELLS, CULTURED; CYCLIC AMP-DEPENDENT PROTEIN KINASES; ENZYME INHIBITORS; EXCITATORY AMINO ACID TRANSPORTER 2; GLUTAMIC ACID; HIPPOCAMPUS; MICE; MICE, KNOCKOUT; NOOTROPIC AGENTS; PIPERAZINES; RATS; SYNAPTIC TRANSMISSION;

EID: 12244313415     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-328X(02)00511-9     Document Type: Article

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