Bone loss detection in rats using a mouse densitometer

Journal of Bone and Mineral Research

Volumn 18, Issue 2, 2003, Pages 370-375

  Binkley, N ^a   Dahl, D B ^a   Engelke, J ^a   Kawahara Baccus, T ^a   Krueger, D ^a   Colman, R J ^b  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b UNIVERSITY OF WISCONSIN   (United States)

Author keywords

Bone mass; DXA; Osteopenia; Ovariectomy; Rat

Indexed keywords

ESTROGEN;

ACCURACY; ANIMAL TISSUE; ARTICLE; BONE DENSITY; BONE MASS; BONE MINERAL; CONTROLLED STUDY; DENSITOMETRY; DUAL ENERGY X RAY ABSORPTIOMETRY; FEMALE; FEMUR; NONHUMAN; OSTEOLYSIS; OSTEOPENIA; RAT;

ANIMALS; BODY WEIGHT; BONE AND BONES; BONE DENSITY; BONE DISEASES, METABOLIC; DENSITOMETRY; FEMALE; FEMUR; MICE; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS;

EID: 12244308636     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/jbmr.2003.18.2.370     Document Type: Article

References (26)

1. Kimmel DB 1996 Animal models for in vivo experimentation in osteoporosis research. In: Marcus R, Feldman D, Kelsey J (eds.) Osteoporosis. Academic Press, San Diego, CA, USA, pp. 671-690.
2. Kalu DN 1991 The ovariectomized rat model of postmenopausal bone loss. Bone Miner 15:175-192.
3. Wronski TJ, Yen CF 1991 The ovariectomized rat as an animal model for postmenopausal bone loss. Cells Mater (Suppl 1):69-74.
4. Anonymous 1994 Guidelines for preclinical and clinical evaluation of agents used in the prevention or treatment of postmenopausal osteoporosis. Division of Metabolism and Endocrine Drug Products: Food and Drug Administration.
5. Griffin MG, Kimble R, Hopfer W, Pacifici R 1993 Dual-energy x-ray absorptiometry of the rat: Accuracy, precision and measurement of bone loss. J Bone Miner Res 8:795-800.
6. Mitlak BH, Schoenfeld D, Neer RM 1994 Accuracy, precision, and utility of spine and whole-skeleton mineral measurements by DXA in rats. J Bone Miner Res 9:119-126.
7. Li X, Takahashi M, Kushida K, Inoue T 1998 The preventive and interventional effects of raloxifene analog (LY117018 HCI) on osteopenia in ovariectomized rats. J Bone Miner Res 13:1005-1010.
8. Kishi T, Hagino H, Kishimoto H, Nagashima H 1998 Bone responses at various skeletal sites to human parathyroid hormone in ovariectomized rats: Effects of long-term administration, withdrawal, and readministration. Bone 22:515-522.
9. Pastoureau P, Chomel A, Bonnet J 1995 Specific evaluation of localized bone mass and bone loss in the rat using dual-energy x-ray absorptiometry subregional analysis. Osteoporos Int 5:143-149.
10. Akiyama Y, Hara K, Kobayashi M, Tomiuga T, Nakamura T 1999 Inhibitory effect of vitamin K2 (menatetrenone) on bone resorption in ovariectomized rats: A histomorphometric and dual energy x-ray absorptiometric study. Jpn J Pharmacol 80:67-74.
11. Gala Paniagua J, Diaz-Curiel M, de la Piedra Gordo C, Castilla Reparaz C, Torralbo Garcia M 1998 Bone mass assessment in rats by dual energy X-ray absorptiometry. Br J Radiol 71:754-758.
12. Lu PW, Briody JN, Howman-Giles R, Trube A, Cowell CT 1994 DXA for bone density measurement in small rats weighing 150-250 grams. Bone 15:199-202.
13. Nagy TR, Clair AL 2000 Precision and accuracy of dual-energy x-ray absorptiometry for determining in vivo body composition of mice. Obes Res 8:392-398.
14. Nagy TR, Prince CW, Li J 2001 Validation of peripheral dual-energy x-ray absorptiometry for the measurement of bone mineral in intact and excised long bones of rats. J Bone Miner Res 16: 1682-1687.
15. Fink C, Cooper HJ, Huebner JL, Guilak F, Kraus VB 2002 Precision and accuracy of a transportable dual-energy x-ray absorptiometry unit for bone mineral measurements in guinea pigs. Calcif Tissue Int 70:164-169.
16. Rosen HN, Tollin S, Balena R, Middlebrooks VL, Beamer WG, Donohue LR, Rosen C, Turner A, Holick M, Greenspan SL 1995 Differentiating between orchiectomized rats and controls using measurements of trabecular bone density: A comparison among DXA, histomorphometry, and peripheral quantitative computerized tomography. Calcif Tissue Int 57:35-39.
17. Sato M 1995 Comparative x-ray densitometry of bones from ovariectomized rats. Bone 17:157S-162S.
18. Grier SJ, Turner AS, Alvis MR 1996 The use of dual-energy x-ray absorptiometry in animals. Invest Radiol 31:50-62.
19. Feely RS, Larkin LM, Halter JB, Dengel DR 2000 Chemical versus dual energy x-ray absorptiometry for detecting age-associated body compositional changes in male rats. Exp Gerontol 35:417-427.
20. Zeni SN, Di Gregorio S, Mautalen C 1999 Bone mass changes during pregnancy and lactation in the rat. Bone 25:681-685.
21. Syversen U, Nordsletten L, Falch JA, Madsen JE, Nilsen OG, Waldum HL 1999 Effect of lifelong nicotine inhalation on bone mass and mechanical properties in female rat femurs. Calcif Tissue Int 65:246-249.
22. Ammann P, Rissoli R, Slosman D, Bonjour JP 1992 Sequential and precise in vivo measurement of bone mineral density in rats using dual-energy x-ray absorptiometry. J Bone Miner Res 7:311-316.
23. Rozenberg S, Vandromme J, Neve J, Aguilera A, Muregancuro A, Peretz A, Kinthaert J, Ham H 1995 Precision and accuracy of in vivo bone mineral measurements in rats using dual-energy x-ray absorptiometry. Osteoporos Int 5:47-53.
24. Bagi CM, DeLeon E, Ammann P, Rizzoli R, Miller SC 1996 Histo-anatomy of the proximal femur in rats: Impact of ovariectomy on bone mass, structure, and stiffness. Anat Rec 245:633-644.
25. Jiang Y, Zhao J, Genant HK, Dequeker J, Geusens P 1998 Bone mineral density and biomechanical properties of spine and femur of ovariectomized rats treated with naproxen. Bone 22:509-514.
26. Ke HZ, Chen HK, Simmons HA, Qi H, Crawford DT, Pirie CM, Chidsey-Frink KL, Ma YF, Jee WSS, Thompson DD 1997 Comparative effects of droloxifene, tamoxifen, and estrogen on bone, serum cholesterol, and uterine histology in the ovariectomized rat model. Bone 20:31-39.