Skin capillary density changes in normal pregnancy and pre-eclampsia

Journal of Hypertension

Volumn 20, Issue 12, 2002, Pages 2439-2443

  Hasan, Khaled M ^a   Manyonda, Isaac T ^a   Ng, Fu Siong ^a   Singer, Donald R J ^a   Antonios, Tarek F T ^a  

^a ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Functional capillary density; Intravital capillary video microscopy; Maximal capillary density; Pre eclampsia syndrome; Rarefaction; Skin capillary density

Indexed keywords

ADAPTATION; ADULT; ANGIOGENESIS; ARTICLE; BLOOD PRESSURE; BLOOD PRESSURE MEASUREMENT; BLOOD PRESSURE REGULATION; CAPILLARY DENSITY; CARDIOVASCULAR RESPONSE; CONTROLLED STUDY; CORRELATION ANALYSIS; ESSENTIAL HYPERTENSION; FEMALE; HEMODYNAMICS; HUMAN; MAJOR CLINICAL STUDY; MICROCIRCULATION; PATHOGENESIS; PREECLAMPSIA; PREGNANCY; PRIORITY JOURNAL; SKIN CAPILLARY; VASCULAR RESISTANCE; VASODILATATION;

EID: 12244302876     PISSN: 02636352     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004872-200212000-00024     Document Type: Article

References (20)

1. Robson SC, Hunter S, Boys RJ, Dunlop W. Serial study of factors influencing changes in cardiac output during human pregnancy. Am J Physiol Heart Circ Physiol 1989; 256:H1060-H1065.
2. Walker JJ. Pre-eclampsia. Lancet 2000; 356:1260-1265.
3. Katz M, Sokal MM. Skin perfusion in pregnancy. Am J Obstet Gynecol 1980; 137:30-33.
4. Linder HR, Reinhart WH, Hanggi W, Katz M, Schneider H. Peripheral capillaroscopic findings and blood rheology during normal pregnancy. Eur J Obstet Gynecol Reprod Biol 1995; 58:141-145.
5. Meekins JW, Pijnenborg R, Hanssens M, McFadyen IR, van Asshe A. A study of placental bed spiral arteries and trophoblast invasion in normal and severe pre-eclamptic pregnancies. Br J Obstet Gynaecol 1994; 101:669-774.
6. Redman CWG. Pre-eclampsia and the placenta. Placenta 1991; 12:301-308.
7. Page NM, Woods RJ, Gardiner SM, Lomthaisong K, Gladwell RT, Butlin DJ, et al. Excessive placental secretion of neurokinin B during the third trimester causes pre-eclampsia. Nature 2000; 405:797-800.
8. D'Antona D, Reis FM, Benedetto C, Evans LW, Groome NP, de Kretser DM, et al. Increased maternal serum activin A but not follistatin levels in pregnant women with hypertensive disorders. J Endocrinol 2000; 165:157-162.
9. Luisi S, Petraglia F, Benedetto C, Nappi RE, Bernadi F, Fadalti M, et al. Serum allopregnanolone levels in pregnant women: Changes during pregnancy, at delivery, and in hypertensive patients. J Clin Endocrinol Metab 2000; 85:2429-2433
10. Florio P, Cobellis L, Luisi S, Ciarmela P, Severi FM, Bocchi C, Petraglia F. Changes in inhibins and activin secretion in healthy and pathological pregnancies. Mol Cell Endocrinol 2001; 180:123-130.
11. Luisi S, Florio P, Reis FM, Petraglia F. Expression and secretion of activin A: Possible physiological and clinical implications. Eur J Endocrinol 2001; 145:225-236.
12. Reis FM, D'Antona D, Petraglia F. Predictive value of hormone measurements in maternal and fetal complications of pregnancy. Endocrinol Rev 2002; 23:230-257.
13. Antonios TFT, Singer DR, Markandu ND, Mortimer PS, MacGregor GA. Structural skin capillary rarefaction in essential hypertension. Hypertension 1999; 33:998-1001.
14. Antonios TFT, Singer DR, Markandu ND, Mortimer PS, MacGregor GA. Rarefaction of skin capillaries in borderline essential hypertension suggests an early structural abnormality. Hypertension 1999; 34:655-658.
15. Antonios TFT, Rattray FE, Singer DR, Markandu ND, Mortimer PS, MacGregor GA. Maximization of skin capillaries during intravital video-microscopy in essential hypertension: Comparison between venous congestion, reactive hyperaemia and core heat load tests. Clin Sci 1999; 97:523-528.
16. Antonios TFT. Microvascular Circulation in Cardiovascular Disease [dissertation]. London: University of London; 1999.
17. Reuvekamp A, Velsing-Aarts FV, Poulina IE, Capello JJ, Duits AJ. Selective deficit of angiogenic growth factors characterises pregnancies complicated by pre-eclampsia. Br J Obstet Gynaecol 1999; 106:1019-1022.
18. Brosens IA, Robertson WB, Dixon HG. The role of the spiral arteries in the pathogenesis of pre-eclampsia. Obstet Gynecol Annu 1972; 1:177-191.
19. Roberts JM, Taylor RN, Goldfien A. Clinical and biochemical evidence of endothelial cell dysfunction in the pregnancy syndrome preeclampsia. Am J Hypertens 1991; 4:700-708.
20. Manyonda IT, Slater DM, Fenske C, Hole D, Choy MY, Wilson C. A role for noradrenaline in pre-eclampsia: Towards a unifying hypothesis for the pathophysiology. Br J Obstet Gynaecol 1998; 105:641-648.