메뉴 건너뛰기




Volumn 12, Issue 8, 2002, Pages 647-653

The effectiveness of hydroxy-methylglutaryl coenzyme A reductase inhibitors (statins) in the elderly is not influenced by apolipoprotein E genotype

Author keywords

Apolipoprotein E genotype; Effectiveness; Pharmacogenetics; Statins

Indexed keywords

APOLIPOPROTEIN A; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR;

EID: 12244296189     PISSN: 0960314X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00008571-200211000-00009     Document Type: Article
Times cited : (21)

References (28)
  • 1
    • 0027987849 scopus 로고
    • Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: The Scandinavian Simvastatine Survival Study
    • Anonymous. Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: The Scandinavian Simvastatine Survival Study. Lancet 1994; 344:1383-1389.
    • (1994) Lancet , vol.344 , pp. 1383-1389
  • 2
    • 0342981862 scopus 로고    scopus 로고
    • The effect of pravastatine on coronary events after myocardial infarction in patients with average cholesterol levels
    • Sacks F, Pfeffer MA, Moye LA, Rouleau JL, Rutherford JD, Cole TG, et al. The effect of pravastatine on coronary events after myocardial infarction in patients with average cholesterol levels. N Eng J Med 1996; 336:1001-1009.
    • (1996) N Eng J Med , vol.336 , pp. 1001-1009
    • Sacks, F.1    Pfeffer, M.A.2    Moye, L.A.3    Rouleau, J.L.4    Rutherford, J.D.5    Cole, T.G.6
  • 3
    • 0032487931 scopus 로고    scopus 로고
    • Prevention of cardiovascular events and death with pravastatine in patients with coronary heart disease and a broad range of initial cholesterol levels
    • Anonymous. Prevention of cardiovascular events and death with pravastatine in patients with coronary heart disease and a broad range of initial cholesterol levels. N Eng J Med 1998; 339:1349-1357.
    • (1998) N Eng J Med , vol.339 , pp. 1349-1357
  • 4
    • 0028883828 scopus 로고
    • Prevention of coronary heart disease with pravastatine in men with hypercholesterolemia
    • Shepherd J, Cobbe SM, Ford I, Isles CG, Lorimer AR, McFarlane PW, et al. Prevention of coronary heart disease with pravastatine in men with hypercholesterolemia. New Eng J Med 1995; 333:1301-1307.
    • (1995) New Eng J Med , vol.333 , pp. 1301-1307
    • Shepherd, J.1    Cobbe, S.M.2    Ford, I.3    Isles, C.G.4    Lorimer, A.R.5    McFarlane, P.W.6
  • 5
    • 0032572086 scopus 로고    scopus 로고
    • Primary prevention of acute coronary events with lovastatine in men and women with average cholesterol levels. Results of AFCAPS/TexCAPS
    • Downs JR, Clearfield M, Weis S, Whitney E, Shapiro DR, Beere PA, et al. Primary prevention of acute coronary events with lovastatine in men and women with average cholesterol levels. Results of AFCAPS/TexCAPS. JAMA 1998; 279:1615-1622.
    • (1998) JAMA , vol.279 , pp. 1615-1622
    • Downs, J.R.1    Clearfield, M.2    Weis, S.3    Whitney, E.4    Shapiro, D.R.5    Beere, P.A.6
  • 6
    • 0037031061 scopus 로고    scopus 로고
    • MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20 536 high-risk individuals: A randomised placebo-controlled trial
    • Heart Protection Study Collaborative Group. MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20 536 high-risk individuals: A randomised placebo-controlled trial. Lancet 2002; 360:7-22.
    • (2002) Lancet , vol.360 , pp. 7-22
  • 7
    • 0019379410 scopus 로고
    • Human apolipoprotein E isoprotein subclasses are genetically determined
    • Zannis VI, Just PW, Breslow JL. Human apolipoprotein E isoprotein subclasses are genetically determined. Am J Hum Genet 1981; 33:11-24.
    • (1981) Am J Hum Genet , vol.33 , pp. 11-24
    • Zannis, V.I.1    Just, P.W.2    Breslow, J.L.3
  • 8
    • 0023860891 scopus 로고
    • Apolipoprotein E polymorphism and atherosclerosis
    • Davignon J, Gregg RE, Sing CF. Apolipoprotein E polymorphism and atherosclerosis. Arteriosclerosis 1988; 8:1-21.
    • (1988) Arteriosclerosis , vol.8 , pp. 1-21
    • Davignon, J.1    Gregg, R.E.2    Sing, C.F.3
  • 9
    • 0031896842 scopus 로고    scopus 로고
    • Lack of interaction of apolipoprotein E phenotype with the lipoprotein response to lovastatin or gemfibrozil in patients with primary hypercholesterolemia
    • Sanllehy C, Casals E, Rodriguez-Villar C, Zambon D, Ojuel J, Ballesta AM, et al. Lack of interaction of apolipoprotein E phenotype with the lipoprotein response to lovastatin or gemfibrozil in patients with primary hypercholesterolemia. Metabolism 1998; 47:560-565.
    • (1998) Metabolism , vol.47 , pp. 560-565
    • Sanllehy, C.1    Casals, E.2    Rodriguez-Villar, C.3    Zambon, D.4    Ojuel, J.5    Ballesta, A.M.6
  • 10
    • 0345818377 scopus 로고    scopus 로고
    • APO E gene and gene-environment effects on plasma lipoprotein-lipid levels
    • Hagberg JM, Wilund KR, Ferrell RE. APO E gene and gene-environment effects on plasma lipoprotein-lipid levels Physiol Genomics 2000; 4:101-108.
    • (2000) Physiol Genomics , vol.4 , pp. 101-108
    • Hagberg, J.M.1    Wilund, K.R.2    Ferrell, R.E.3
  • 11
    • 0034332915 scopus 로고    scopus 로고
    • Apolipoprotein E genotypes and response of plasma lipids and progression-regression of coronary atherosclerosis to lipid-lowering drug therapy
    • Ballantyne CM, Herd JA, Stein EA, Ferlic LL, Dunn JK, Gotto AM Jr, et al. Apolipoprotein E genotypes and response of plasma lipids and progression-regression of coronary atherosclerosis to lipid-lowering drug therapy. J Am Coll Cardiol 2000; 36:1572-1578.
    • (2000) J Am Coll Cardiol , vol.36 , pp. 1572-1578
    • Ballantyne, C.M.1    Herd, J.A.2    Stein, E.A.3    Ferlic, L.L.4    Dunn, J.K.5    Gotto A.M., Jr.6
  • 12
    • 0030895889 scopus 로고    scopus 로고
    • A comparative study of the efficacy of simvastatin and gemfibrozil in combined hyperlipoproteinemia: Prediction of response by baseline lipids, apo E genotype, lipoprotein (a) and insulin
    • Nestel P, Simons L, Barter P, Clifton P, Colquhoun D, Hamilton-Craig I, et al. A comparative study of the efficacy of simvastatin and gemfibrozil in combined hyperlipoproteinemia: Prediction of response by baseline lipids, apo E genotype, lipoprotein (a) and insulin. Atherosclerosis 1997; 129:231-239.
    • (1997) Atherosclerosis , vol.129 , pp. 231-239
    • Nestel, P.1    Simons, L.2    Barter, P.3    Clifton, P.4    Colquhoun, D.5    Hamilton-Craig, I.6
  • 13
    • 0028901424 scopus 로고
    • Effect of apolipoprotein E and A-IV phenotypes on the low density lipoprotein response to HMG CoA reductase inhibitor therapy
    • Ordovas JM, Lopez-Miranda J, Perez-Jimenez F, Rodriguez C, Park JS, Cole T, et al. Effect of apolipoprotein E and A-IV phenotypes on the low density lipoprotein response to HMG CoA reductase inhibitor therapy. Atherosclerosis 1995; 113:157-166.
    • (1995) Atherosclerosis , vol.113 , pp. 157-166
    • Ordovas, J.M.1    Lopez-Miranda, J.2    Perez-Jimenez, F.3    Rodriguez, C.4    Park, J.S.5    Cole, T.6
  • 14
    • 0027199749 scopus 로고
    • The response to lovastatin treatment in patients with heterozygous familial hypercholesterolemia is modulated by apolipoprotein E polymorphism
    • Carmena R, Roederer G, Mailloux H, Lussier-Cacan S, Davignon J. The response to lovastatin treatment in patients with heterozygous familial hypercholesterolemia is modulated by apolipoprotein E polymorphism. Metabolism 1993; 42:895-901.
    • (1993) Metabolism , vol.42 , pp. 895-901
    • Carmena, R.1    Roederer, G.2    Mailloux, H.3    Lussier-Cacan, S.4    Davignon, J.5
  • 15
    • 0025950550 scopus 로고
    • Effect of apolipoprotein E polymorphism and Xbal polymorphism of apolipoprotein B on response to lovastatin treatment in familial and nonfamilial hypercholesterolaemia
    • Ojala JP, Helve E, Ehnholm C, Aalto-Setala K, Kontula KK, Tikkanen MJ. Effect of apolipoprotein E polymorphism and Xbal polymorphism of apolipoprotein B on response to lovastatin treatment in familial and nonfamilial hypercholesterolaemia. J Intern Med 1991; 230:397-405.
    • (1991) J Intern Med , vol.230 , pp. 397-405
    • Ojala, J.P.1    Helve, E.2    Ehnholm, C.3    Aalto-Setala, K.4    Kontula, K.K.5    Tikkanen, M.J.6
  • 16
    • 0025313801 scopus 로고
    • Influence of apo E polymorphism on the response to simvastatin treatment in patients with heterozygous familial hypercholesterolemia
    • De Knijff P, Stalenhoef AF, Mol MJ, Gevers Leuven JA, Smit J, Erkelens DW, et al. Influence of apo E polymorphism on the response to simvastatin treatment in patients with heterozygous familial hypercholesterolemia, Atherosclerosis 1990; 83:89-97.
    • (1990) Atherosclerosis , vol.83 , pp. 89-97
    • De Knijff, P.1    Stalenhoef, A.F.2    Mol, M.J.3    Gevers Leuven, J.A.4    Smit, J.5    Erkelens, D.W.6
  • 17
    • 0025105149 scopus 로고
    • The influence of apolipoprotein E phenotype on the response to lovastatin therapy in patients with heterozygous familial hypercholesterolemia
    • O'Malley JP, Illingworth DR. The influence of apolipoprotein E phenotype on the response to lovastatin therapy in patients with heterozygous familial hypercholesterolemia. Metabolism 1990; 39:150-154.
    • (1990) Metabolism , vol.39 , pp. 150-154
    • O'Malley, J.P.1    Illingworth, D.R.2
  • 18
    • 0036090989 scopus 로고    scopus 로고
    • Effect of apoE genotype on the hypolipidaemic response to pravastatin in an outpatient setting
    • Pena R, Lahoz C, Mostaza JM, Jimenez J, Subirats E, Pinto X, et al. Effect of apoE genotype on the hypolipidaemic response to pravastatin in an outpatient setting, J Intern Med 2002; 261:518-525.
    • (2002) J Intern Med , vol.261 , pp. 518-525
    • Pena, R.1    Lahoz, C.2    Mostaza, J.M.3    Jimenez, J.4    Subirats, E.5    Pinto, X.6
  • 19
    • 0034724089 scopus 로고    scopus 로고
    • The apolipoprotein epsilon4 allele determines prognosis and the effect on prognosis of simvastatin in survivors of myocardial infarction: A substudy of the Scandinavian Simvastatin Survival Study
    • Gerdes LU, Gerdes C, Kervinen K, Savolainen M, Klausen IC, Hansen PS, et al. The apolipoprotein epsilon4 allele determines prognosis and the effect on prognosis of simvastatin in survivors of myocardial infarction: A substudy of the Scandinavian Simvastatin Survival Study. Circulation 2000; 101:1366-1371.
    • (2000) Circulation , vol.101 , pp. 1366-1371
    • Gerdes, L.U.1    Gerdes, C.2    Kervinen, K.3    Savolainen, M.4    Klausen, I.C.5    Hansen, P.S.6
  • 20
    • 0025767240 scopus 로고
    • Determinants of disease and disability in the elderly: The Rotterdam Elderly Study
    • Hofman A, Grobbee DE, de Jong PT, van den Ouweland FA. Determinants of disease and disability in the elderly: The Rotterdam Elderly Study. Eur J Epidemiol 1991; 7:403-422.
    • (1991) Eur J Epidemiol , vol.7 , pp. 403-422
    • Hofman, A.1    Grobbee, D.E.2    De Jong, P.T.3    Van den Ouweland, F.A.4
  • 21
    • 0030826182 scopus 로고    scopus 로고
    • Common carotid intima-media thickness and risk of stroke and myocardial infarction: The Rotterdam Study
    • Bots ML, Hoes AW, Koudstaal PJ, Hofman A, Grobbee DE. Common carotid intima-media thickness and risk of stroke and myocardial infarction: The Rotterdam Study. Circulation 1997; 96:1432-1437.
    • (1997) Circulation , vol.96 , pp. 1432-1437
    • Bots, M.L.1    Hoes, A.W.2    Koudstaal, P.J.3    Hofman, A.4    Grobbee, D.E.5
  • 22
    • 0028181727 scopus 로고
    • Assessing possible hazards of reducing serum cholesterol
    • Law MR, Thompson SG, Wald NJ. Assessing possible hazards of reducing serum cholesterol. BMJ 1994; 308:373-379.
    • (1994) BMJ , vol.308 , pp. 373-379
    • Law, M.R.1    Thompson, S.G.2    Wald, N.J.3
  • 23
    • 0004100810 scopus 로고
    • Oslo: WHO Collaborating centre for drug statistics methodology - Nordic Council on medicines
    • WHO. Guidelines for ATC Classification. Oslo: WHO Collaborating centre for drug statistics methodology - Nordic Council on medicines, 1990.
    • (1990) Guidelines for ATC Classification
  • 24
    • 0028988736 scopus 로고
    • The apolipoprotein E epsilon 2 allele is associated with an increased risk of early onset Alzheimer's disease and a reduced survival
    • van Duijn CM, de Knijff P, Wehnert A, De Voecht J, Bronzova JB, Havekes LM, et al. The apolipoprotein E epsilon 2 allele is associated with an increased risk of early onset Alzheimer's disease and a reduced survival. Ann Neurol 1995; 37:605-610.
    • (1995) Ann Neurol , vol.37 , pp. 605-610
    • Van Duijn, C.M.1    De Knijff, P.2    Wehnert, A.3    De Voecht, J.4    Bronzova, J.B.5    Havekes, L.M.6
  • 25
    • 0025801744 scopus 로고
    • Apolipoprotein E genotyping by one-stage PCR
    • Wenham PR, Price WH, Blandell G. Apolipoprotein E genotyping by one-stage PCR. Lancet 1991; 337:1158-1159.
    • (1991) Lancet , vol.337 , pp. 1158-1159
    • Wenham, P.R.1    Price, W.H.2    Blandell, G.3
  • 26
    • 0029787622 scopus 로고    scopus 로고
    • Nontraditional epidemiologic approaches in the analysis of gene - Environment interaction: Case-control studies with no controls!
    • Khoury MJ, Flanders WD. Nontraditional epidemiologic approaches in the analysis of gene - Environment interaction: Case-control studies with no controls! Am J Epidemiol 1996; 144:207-213.
    • (1996) Am J Epidemiol , vol.144 , pp. 207-213
    • Khoury, M.J.1    Flanders, W.D.2
  • 27
    • 0033543116 scopus 로고    scopus 로고
    • Age-dependent association of apolipoprotein E genotype with coronary and aortic atherosclerosis in middle-aged men: An autopsy study
    • Ilveskoski E, Perola M, Lehtimaki T, Laippala P, Savolainen V, Pajarinen J, et al. Age-dependent association of apolipoprotein E genotype with coronary and aortic atherosclerosis in middle-aged men: An autopsy study. Circulation 1999; 100:608-613.
    • (1999) Circulation , vol.100 , pp. 608-613
    • Ilveskoski, E.1    Perola, M.2    Lehtimaki, T.3    Laippala, P.4    Savolainen, V.5    Pajarinen, J.6
  • 28
    • 0032495541 scopus 로고    scopus 로고
    • The role of a common variant of the cholesteryl ester transfer protein gene in the progression of coronary atherosclerosis
    • Kuivenhoven J, Jukema JW, Zwinderman AH, de Knijff P, McPherson R, Bruschke AVG, et al. The role of a common variant of the cholesteryl ester transfer protein gene in the progression of coronary atherosclerosis. New Eng J Med 1998; 338:86-93.
    • (1998) New Eng J Med , vol.338 , pp. 86-93
    • Kuivenhoven, J.1    Jukema, J.W.2    Zwinderman, A.H.3    De Knijff, P.4    McPherson, R.5    Bruschke, A.V.G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.