메뉴 건너뛰기




Volumn 129, Issue 2, 1997, Pages 231-239

A comparative study of the efficacy of simvastatin and gemfibrozil in combined hyperlipoproteinemia: Prediction of response by baseline lipids, apo E genotype, lipoprotein(a) and insulin

Author keywords

combined hyperlipoproteinemia; gemfibrozil; predictors of response; simvastatin

Indexed keywords

APOLIPOPROTEIN; CHOLESTEROL; GEMFIBROZIL; INSULIN; SIMVASTATIN; TRIACYLGLYCEROL; VERY LOW DENSITY LIPOPROTEIN;

EID: 0030895889     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0021-9150(96)06031-5     Document Type: Article
Times cited : (74)

References (28)
  • 1
    • 0015796295 scopus 로고
    • Hyperlipidemia in coronary heart disease, II: genetic analysis in 176 families and delineation of a new inherited disorder, combined hyperlipidemia
    • Goldstein JL, Schrott HG, Hazzard WR, Bierman EL, Motulsky AG. Hyperlipidemia in coronary heart disease, II: genetic analysis in 176 families and delineation of a new inherited disorder, combined hyperlipidemia. J Clin Invest 1973;52:1544.
    • (1973) J Clin Invest , vol.52 , pp. 1544
    • Goldstein, J.L.1    Schrott, H.G.2    Hazzard, W.R.3    Bierman, E.L.4    Motulsky, A.G.5
  • 3
    • 0029057589 scopus 로고
    • Insulin resistance and lipoprotein metabolism
    • Taskinen M. Insulin resistance and lipoprotein metabolism. Curr Opin Lipidol 1995;6:153.
    • (1995) Curr Opin Lipidol , vol.6 , pp. 153
    • Taskinen, M.1
  • 4
    • 0026762806 scopus 로고
    • Prevalence of familial lipoprotein disorders in patients with premature coronary artery disease
    • Genest JJ, Martin-Munley S, McNamara JR et al. Prevalence of familial lipoprotein disorders in patients with premature coronary artery disease. Circulation 1992;85:2025.
    • (1992) Circulation , vol.85 , pp. 2025
    • Genest, J.J.1    Martin-Munley, S.2    McNamara, J.R.3
  • 5
    • 0003446541 scopus 로고
    • Canberra: National Heart Foundation and Australian Institute of Health
    • Risk Factor Prevalence Study: Survey No 3 1989, Canberra: National Heart Foundation and Australian Institute of Health, 1990.
    • (1990) Risk Factor Prevalence Study: Survey No 3 1989
  • 6
    • 0028019136 scopus 로고
    • Pravastatin effectively lowers LDL cholesterol in familial combined hyperlipidemia without changing LDL subclass pattern
    • Franceschini G, Cassinotti M, Vecchio G et al. Pravastatin effectively lowers LDL cholesterol in familial combined hyperlipidemia without changing LDL subclass pattern. Arterioscler Thromb 1994;14:1569.
    • (1994) Arterioscler Thromb , vol.14 , pp. 1569
    • Franceschini, G.1    Cassinotti, M.2    Vecchio, G.3
  • 7
    • 0027485431 scopus 로고
    • Plasma lipoproteins and progression of coronary artery disease evaluated by angiography and clinical events
    • Phillips NR, Waters D, Havel RJ. Plasma lipoproteins and progression of coronary artery disease evaluated by angiography and clinical events. Circulation 1993;88:2762.
    • (1993) Circulation , vol.88 , pp. 2762
    • Phillips, N.R.1    Waters, D.2    Havel, R.J.3
  • 9
    • 0015847114 scopus 로고
    • Quantitative determination of serum triglycerides by the use of enzymes
    • Bucolo G, David H. Quantitative determination of serum triglycerides by the use of enzymes. Clin Chem 1973;19:476.
    • (1973) Clin Chem , vol.19 , pp. 476
    • Bucolo, G.1    David, H.2
  • 10
    • 0014876627 scopus 로고
    • Rapid method for the isolation of lipoproteins from human serum by precipitation with polyanions
    • Burstein M, Scholnick HR, Morfin R. Rapid method for the isolation of lipoproteins from human serum by precipitation with polyanions. J Lipid Res 1970;11:583.
    • (1970) J Lipid Res , vol.11 , pp. 583
    • Burstein, M.1    Scholnick, H.R.2    Morfin, R.3
  • 11
    • 0015348189 scopus 로고
    • Estimation of the concentration of low density lipoprotein cholesterol in plasma without the use of ultracentrifuge
    • Friedewald WT, Levy RI, Fredrickson DS. Estimation of the concentration of low density lipoprotein cholesterol in plasma without the use of ultracentrifuge. Clin Chem 1972;18:499.
    • (1972) Clin Chem , vol.18 , pp. 499
    • Friedewald, W.T.1    Levy, R.I.2    Fredrickson, D.S.3
  • 12
    • 0025257612 scopus 로고
    • Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HhaI
    • Hixson JE, Vernia DT. Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HhaI. J Lipid Res 1990;31:545.
    • (1990) J Lipid Res , vol.31 , pp. 545
    • Hixson, J.E.1    Vernia, D.T.2
  • 13
    • 0020060090 scopus 로고
    • Identification of multiple subclasses of plasma low density lipoproteins in normal humans
    • Krauss RM, Burke DJ. Identification of multiple subclasses of plasma low density lipoproteins in normal humans. J Lipid Res 1982;23:97.
    • (1982) J Lipid Res , vol.23 , pp. 97
    • Krauss, R.M.1    Burke, D.J.2
  • 14
    • 0028962401 scopus 로고
    • Fibrates and statins in the treatment of hyperlipidaemia: an appraisal of their efficacy and safety
    • Shepherd J. Fibrates and statins in the treatment of hyperlipidaemia: an appraisal of their efficacy and safety. Eur Heart J 1995;16:5.
    • (1995) Eur Heart J , vol.16 , pp. 5
    • Shepherd, J.1
  • 15
    • 0028842308 scopus 로고
    • Genetic basis of lipoprotein disorders
    • Dammerman M, Breslow JL. Genetic basis of lipoprotein disorders. Circulation 1995;91:505.
    • (1995) Circulation , vol.91 , pp. 505
    • Dammerman, M.1    Breslow, J.L.2
  • 16
    • 0027199749 scopus 로고
    • The response to lovastatin treatment in patients with heterozygous familial hypercholesterolemia is modulated by apoliporotein E polymorphism
    • Carmena R, Roederer G, Mailloux H, Lussier-Cacan S, Davignon J. The response to lovastatin treatment in patients with heterozygous familial hypercholesterolemia is modulated by apoliporotein E polymorphism. Metabolism 1993;42:895.
    • (1993) Metabolism , vol.42 , pp. 895
    • Carmena, R.1    Roederer, G.2    Mailloux, H.3    Lussier-Cacan, S.4    Davignon, J.5
  • 17
    • 0025950550 scopus 로고
    • Effect of apolipoprotein E polymorphism and Xbal polymorphism of apolipoprotein B on response to lovastatin treatment in familial and non-familial hypercholesterolaemia
    • Ojala JP, Helve E, Ehnholm C, Aalto-Setala K, Kontula KK, Tikkanen MJ. Effect of apolipoprotein E polymorphism and Xbal polymorphism of apolipoprotein B on response to lovastatin treatment in familial and non-familial hypercholesterolaemia. J Int Med 1991;230:397.
    • (1991) J Int Med , vol.230 , pp. 397
    • Ojala, J.P.1    Helve, E.2    Ehnholm, C.3    Aalto-Setala, K.4    Kontula, K.K.5    Tikkanen, M.J.6
  • 18
    • 0027438889 scopus 로고
    • Postprandial changes in apolipoprotein(a) concentration of triglyceride-rich lipoproteins can be reproduced by in vitro incubation: implications for underlying mechanism
    • Sullivan DR, Lam CWK, Jessup W, Dean RT, Hensley WJ. Postprandial changes in apolipoprotein(a) concentration of triglyceride-rich lipoproteins can be reproduced by in vitro incubation: implications for underlying mechanism. Atherosclerosis 1993;103:139.
    • (1993) Atherosclerosis , vol.103 , pp. 139
    • Sullivan, D.R.1    Lam, C.W.K.2    Jessup, W.3    Dean, R.T.4    Hensley, W.J.5
  • 19
    • 0026495515 scopus 로고
    • Comparative multicentre trial of the efficacy and tolerability of ciprofibrate and simvastatin in the treatment of mixed type IIB hyperlipoproteinaemias
    • Farnier M, Truong-Tan N, Regy C. Comparative multicentre trial of the efficacy and tolerability of ciprofibrate and simvastatin in the treatment of mixed type IIB hyperlipoproteinaemias. J Drug Dev 1992;5:13.
    • (1992) J Drug Dev , vol.5 , pp. 13
    • Farnier, M.1    Truong-Tan, N.2    Regy, C.3
  • 20
    • 0027285331 scopus 로고
    • Ciprofibrate therapy normalises the atherogenic low-density lipoprotein subspecies profile in combined hyperlipidemia
    • Bruckert E, Dejager S, Chapman MJ. Ciprofibrate therapy normalises the atherogenic low-density lipoprotein subspecies profile in combined hyperlipidemia. Atherosclerosis 1993;100:91.
    • (1993) Atherosclerosis , vol.100 , pp. 91
    • Bruckert, E.1    Dejager, S.2    Chapman, M.J.3
  • 21
    • 0028125174 scopus 로고
    • Changes in composition and distribution of LDL subspecies in hypertriglyceridemic and hypercholesterolemic patients during gemfibrozil therapy
    • Yuan J, Tsai MY, Hunninghake DB. Changes in composition and distribution of LDL subspecies in hypertriglyceridemic and hypercholesterolemic patients during gemfibrozil therapy. Atherosclerosis 1994;110:1.
    • (1994) Atherosclerosis , vol.110 , pp. 1
    • Yuan, J.1    Tsai, M.Y.2    Hunninghake, D.B.3
  • 22
    • 0027502421 scopus 로고
    • Susceptibility of small, dense, low-density lipoproteins to oxidative modification in subjects with the atherogenic lipoprotein phenotype, pattern B
    • Chait A, Brazg RL, Tribble DL, Krauss RM. Susceptibility of small, dense, low-density lipoproteins to oxidative modification in subjects with the atherogenic lipoprotein phenotype, pattern B. Am J Med 1993;94:350.
    • (1993) Am J Med , vol.94 , pp. 350
    • Chait, A.1    Brazg, R.L.2    Tribble, D.L.3    Krauss, R.M.4
  • 23
    • 0028273352 scopus 로고
    • Comparative efficacy and safety of micronized fenofibrate and simvastatin in patients with primary type IIa or IIb hyperlipidemia
    • Farnier M, Bonnefous F, Debbas N, Irvine A. Comparative efficacy and safety of micronized fenofibrate and simvastatin in patients with primary type IIa or IIb hyperlipidemia. Arch Intern Med 1994;154:441.
    • (1994) Arch Intern Med , vol.154 , pp. 441
    • Farnier, M.1    Bonnefous, F.2    Debbas, N.3    Irvine, A.4
  • 24
    • 0026680805 scopus 로고
    • Effects of lovastatin therapy on very-low-density lipoprotein triglyceride metabolism in subjects with combined hyperlipidemia: evidence for reduced assembly and secretion of triglyceride-rich lipoproteins
    • Arad Y, Ramakrishnan R, Ginsberg HN. Effects of lovastatin therapy on very-low-density lipoprotein triglyceride metabolism in subjects with combined hyperlipidemia: evidence for reduced assembly and secretion of triglyceride-rich lipoproteins. Metabolism 1992;41:487.
    • (1992) Metabolism , vol.41 , pp. 487
    • Arad, Y.1    Ramakrishnan, R.2    Ginsberg, H.N.3
  • 25
    • 0027471761 scopus 로고
    • Simvastatin improves chylomicron remnant removal in familial combined hyperlipidemia without changing chylomicron conversion
    • Cabezas MC, de Bruin TWA, Kock LAW et al. Simvastatin improves chylomicron remnant removal in familial combined hyperlipidemia without changing chylomicron conversion. Metabolism 1993;42:497.
    • (1993) Metabolism , vol.42 , pp. 497
    • Cabezas, M.C.1    De Bruin, T.W.A.2    Kock, L.A.W.3
  • 26
    • 0027243757 scopus 로고
    • Effect of gemfibrozil and lovastatin on postprandial lipoprotein clearance in the hypoalphalipoproteinemia and hypertriglyceridemia syndrome
    • Simo IE, Yakichuk JA, Ooi TC. Effect of gemfibrozil and lovastatin on postprandial lipoprotein clearance in the hypoalphalipoproteinemia and hypertriglyceridemia syndrome. Atherosclerosis 1993;100:55.
    • (1993) Atherosclerosis , vol.100 , pp. 55
    • Simo, I.E.1    Yakichuk, J.A.2    Ooi, T.C.3
  • 27
    • 0025000460 scopus 로고
    • Influence of lovastatin on concentrations and composition of lipoprotein subfractions
    • Nozaki S, Lena Vega G, Haddox RJ, Dolan ET, Grundy SM. Influence of lovastatin on concentrations and composition of lipoprotein subfractions. Atherosclerosis 1990;84:101.
    • (1990) Atherosclerosis , vol.84 , pp. 101
    • Nozaki, S.1    Lena Vega, G.2    Haddox, R.J.3    Dolan, E.T.4    Grundy, S.M.5
  • 28
    • 0028938714 scopus 로고
    • A comparison between the effects of gemfibrozil and simvastatin on insulin sensitivity in patients with non-insulin- dependent diabetes mellitus and hyperlipoproteinemia
    • Ohrvall M, Lithell H, Johansson J, Vessby B. A comparison between the effects of gemfibrozil and simvastatin on insulin sensitivity in patients with non-insulin- dependent diabetes mellitus and hyperlipoproteinemia. Metabolism 1995;44:212.
    • (1995) Metabolism , vol.44 , pp. 212
    • Ohrvall, M.1    Lithell, H.2    Johansson, J.3    Vessby, B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.