L-Arginine-Induced Vasodilation of the Renal Vasculature Is Preserved in Uremic Type 1 Diabetic Patients after Kidney and Pancreas but not after Kidney-Alone Transplantation

Diabetes Care

Volumn 27, Issue 4, 2004, Pages 947-954

  De Cobelli, Francesco ^a   Fiorina, Paolo ^a   Perseghin, Gianluca ^a   Magnone, Marta ^a   Venturini, Massimo ^a   Zerbini, Gianpaolo ^a   Zanello, Alessandro ^a   Mazzolari, Gabriella ^a   Monti, Lucilla ^a   Di Carlo, Valerio ^a   Secchi, Antonio ^a   Del Maschio, Alessandro ^a  

^a VITA SALUTE SAN RAFFAELE UNIVERSITY   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE;

ADULT; AGED; ARTICLE; BLOOD FLOW VELOCITY; BLOOD VESSEL REACTIVITY; CLINICAL ARTICLE; COMORBIDITY; CONTROLLED STUDY; FEMALE; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; KIDNEY BLOOD FLOW; KIDNEY FAILURE; KIDNEY TRANSPLANTATION; KIDNEY VASCULAR RESISTANCE; MALE; PANCREAS TRANSPLANTATION; POSTOPERATIVE PERIOD; VASODILATATION;

ADULT; ARGININE; BLOOD FLOW VELOCITY; DIABETES MELLITUS, TYPE 1; FEMALE; HUMANS; KIDNEY; KIDNEY TRANSPLANTATION; MAGNETIC RESONANCE ANGIOGRAPHY; MALE; MIDDLE AGED; PANCREAS TRANSPLANTATION; RENAL CIRCULATION; UREMIA; VASCULAR RESISTANCE; VASODILATION;

EID: 12144286218     PISSN: 01495992     EISSN: None     Source Type: Journal    
DOI: 10.2337/diacare.27.4.947     Document Type: Article

References (42)

1. Johnstone MT, Creager SJ, Scales KM, Cusco JA, Lee BK, Creager MA: Impaired endothelium-dependent vasodilation in patients with insulin-dependent diabetes mellitus. Circulation 88:2510-2516, 1993
2. Pohl U, Busse R, Bassenge E: Crucial role of endothelium in the vasodilator response to increased flow in vivo. Hypertension 8:37-44, 1986
3. Sarman B, Toth M, Somogyi A: Role of endothelin-1 in diabetes mellitus. Diabetes Metab Rev 14:171-175, 1998
4. Schernthaner G, Schwarzer C, Kuzmits R, Muller MM, Klem U, Freyler H: Increased angiotensin-converting enzyme activity in diabetes mellitus: analysis of diabetes type, state of metabolic control and occurrence of diabetic vascular disease. J Clin Pathol 37:307-312, 1984
5. Palmer RM, Ferrige AG, Moncada S: Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature 327:524-526, 1987
6. Fields CE, Makhoul RG: Vasomotor tone and the role of nitric oxide. Semin Vasc Surg 11:181-192, 1998
7. Schmidt HH, Nau H, Wittfoht W, Gerlach J, Prescher KE, Klein MM, Niroomand F, Bohme E: Arginine is a physiological precursor of endothelium-derived nitric oxide. Eur J Pharmacol 154:213-216, 1988
8. Palmer RM, Ashton DS, Moncada S: Vascular endothelial cells synthesize nitric oxide from L-arginine. Nature 333:664-666, 1998
9. Moncada S, Higgs A: The L-argininenitric oxide pathway. N Engl J Med 329: 2002-2012, 1993
10. Choen RA: The role of nitric oxide and other endothelium-derived vasoctive substances in vascular disease. Prog Cardiovasc Dis 38:105-128, 1995
11. Tooke JE: The microcirculation in diabetes. Diabet Med 4:189-196, 1987
12. Delles C, Schneider MP, Oehmer S, Fleischmann EH, Schmieder RE: L-Arginine-induced vasodilation of the renal vasculature is not altered in hypertensive patients with type 2 diabetes. Diabetes Care 26:1836-1840, 2003
13. Costa e Forti A, Fonteles MC: Decreased endothelium dependent relaxation (nitric oxide) in diabetic kidneys. Horm Metab Res 30:55-57, 1998
14. Bello E, Caramelo C, Martell N, Gonzalez J, Lopez MD, Ruilope LM, Gonzalez FR, Rovira AM, Gazapo R, Soldevilla MJ, Casado S: Impairment of renal vasodilation with L-arginine is related to more severe disease in untreated hypertensive patients. Hypertension 38:907-912, 2001
15. Lind L, Hall J, Larsson A, Annuk M, Fellstrom B, and Litchell H: Evaluation of endothelium-dependent vasodilation in the human peripheral circulation. Clin Physiol 20:440-448, 2000
16. Tousoulis D, Davies G, Tentolouris C, Crake T, Toutouzas P: Coronary stenosis dilation induced by L-arginine. Lancet 349:1812-1813, 1997
17. Wallace AW, Ratcliffe MB, Galindez D, Kong JS: L-arginine infusion dilates coronary vasculature in patients undergoing coronary bypass surgery. Anesthesiology 90:1577-1586, 1999
18. Lee VS, Spritzer CE, Carroll BA, Pool LG, Bernstein MA, Heinle SK, MacFall JR: Flow quantification using fast cine phase-contrast MR imaging, conventional cine phase-contrast MR imaging, and Doppler sonography: in vitro and in vivo validation. AJR Am J Roentgenol 169:1125-1131, 1997
19. Debatin JF, Ting RH, Wegmuller H, Sommer FG, Fredrickson JO, Brosnan TJ, Bowman BS, Myers BD, Herfkens RJ, Pelc NJ: Renal artery blood flow: quantification with phase-contrast MR imaging with and without breath holding. Radiology 190:371-378, 1994
20. Schoenberg SO, Knopp MV, Bock M, Kallinowski F, Just A, Essig M, Hawighorst H, Schad L, van Kaick G: Renal artery stenosis: grading of hemodynamic changes with cine phase-contrast MR blood flow measurements. Radiology 203:45-53, 1997
21. De Cobelli F, Mellone R, Salvioni M, Vanzulli A, Sironi S, Manunta P, Lanzani C, Bianchi G, Del Maschio A: Renal artery stenosis: value of screening with three-dimensional phase-contrast MR angiography with a phased-array multicoil. Radiology 201:697-703, 1996
22. Gedroyc WMW, Negus R, Al-Kutoubi, Palmer A, Taube D, Hulme B: Magnetic resonance angiography of renal transplants. Lancet 28:789-791, 1992
23. Wolf RL, King BF, Torres VE, Wilson DM, Ehman RL: Measurements of normal renal artery blood flow: cine phase-contrast MR imaging vs clearance of p-aminohippurate. AJR Am J Roentgenol 161:995-1002, 1993
24. Sommer G, Corrigan G, Fredrickson J, Sawyer-Glover A, Liao JR, Myers B, Pelc N: Renal blood flow: measurements in vivo with spiral MR imaging. Radiology 208:729-734, 1998
25. Salvatierra O Jr, Singh T, Shifrin R, Conley S, Alexander S, Tanney D, Lemley K, Sarwal M, Mackie F, Alfrey E, Orlandi P, Zarins C, Herfkens R: Successful transplantation of adult-sized kidneys into infants requires maintenance of high aortic blood flow. Transplantation 66:819-823, 1998
26. Fiorina P, La Rocca E, Venturini M, Minicucci F, Fermo I, Paroni R, D'Angelo A, Sblendido M, Di Carlo V, Cristallo M, Del Maschio A, Pozza G, Secchi A: Effects of kidney-pancreas transplantation on atherosclerotic risk factors and endothelial function in patients with uremia and type 1 diabetes. Diabetes 50:496-501, 2001
27. La Rocca E, Fiorina P, di Carlo V, Astorri E, Rossetti C, Lucignani G, Fazio F, Giudici D, Cristallo M, Bianchi G, Pozza G, Secchi A: Cardiovascular outcomes after kidney-pancreas and kidney-alone transplantation. Kidney Int 60:1964-1971, 2001
28. Sambataro M, Thomaseth K, Pacini G, Robaudo C, Carraro A, Bruseghin M, Brocco E, Abaterusso C, DeFerrari G, Fioretto P, Maioli M, Tonolo GC, Crepaldi G, Nosadini R: Plasma clearance rate of 51Cr-EDTA provides a precise and convenient technique for measurement of glomerular filtration rate in diabetic humans. J Am Soc Nephrol 7:118-127, 1996
29. Schlaich MP, Jacobi J, John S, Delles C, Fleischmann I, Schmeider RE: Is L-arginine infusion an adequate tool to assess endothelium-dependent vasodilation of the human renal vasculature? Clin Sci 99: 293-302, 2000
30. Veelken R, Hilgers KF, Hartner A, Haas A, Bohmer KP, Sterzel RB: Nitric oxide synthase isoforms and glomerular hyperfiltration in early diabetic nephropathy. J Am Soc Nephrol 11:71-79, 2000
31. Ross R: The pathogenesis of atherosclerosis: a perspective for the 1990's. Nature 362:801-809, 1993
32. Benzuly KH, Padgett RC, Kaul S, Piegors DJ, Armstrong ML, Heistad DD: Functional improvement precedes structural regression of atherosclerosis. Circulation 89:1810-1818, 1994
33. Chiarelli F, Cipollone F, Romano F, Tumini S, Costantini F, di Ricco L, Pomilio M, Pierdomenico SD, Marini M, Cuccurullo F, Mezzetti A: Increased circulating nitric oxide in young patients with type 1 diabetes and persistent microalbuminuria: relation to glomerular hyperfiltration. Diabetes 49:1258-1263, 2000
34. Fioretto P, Steffes MW, Sutherland DER, Goetz FC, Mauer M: Reversal of lesions of diabetic nephropathy after pancreas transplantation. N Engl J Med 339:69-75, 1998
35. Enderle MD, Benda N, Schmuelling RM, Haering HU, Pfohl M: Preserved endothelial function in IDDM patients, but not in NIDDM patients, compared with healthy subjects. Diabetes Care 21:271-277, 1998
36. Ido Y, Vindigni A, Chang K, Stramm L, Chance R, Heath WF, DiMarchi RD, Di Cera E, Williamson JR: Prevention of vascular and neural dysfunction in diabetic rats by C-peptide. Science 277:563-566, 1997
37. Giugliano D, Marfella R, Verrazzo G, Acampora R, Nappo F, Ziccardi P, Coppola L, D'Onofrio F: L-arginine for testing endothelium-dependent vascular functions in health and disease. Am J Physiol 273:E606-E612, 1997
38. Giugliano D, Marfella R, Verrazzo G, Acampora R, Coppola L, Cozzolino D, D'Onofrio F: The vascular effects of L-arginine in humans: the role of endogenous insulin. J Clin Invest 99:433-438, 1997
39. Colberg SR, Parson HK, Holton DR, Nunnold T, Vinik AI: Cutaneous blood flow in type 2 diabetic individuals after an acute bout of maximal exercise. Diabetes Care 26:1883-1888, 2003
40. Vinik AI, Erbas T, Park TS, Stansberry KB, Scanelli JA, Pittenger GL: Dermal neurovascular dysfunction in type 2 diabetes. Diabetes Care 24:1468-1475, 2001
41. Caballero AE, Arora S, Saouaf R, Lim SC, Smakowski P, Park JY, King GL, LoGerfo FW, Horton ES, Veves A: Microvascular and macrovascular reactivity is reduced in subjects at risk for type 2 diabetes. Diabetes 48:1856-1862, 1999
42. Facchini FS, DoNascimento C, Reaven GM, Yip JW, Ni XP, Humphreys MH: Blood pressure, sodium intake, insulin resistance, and urinary nitrate excretion. Hypertension 33:1008-1012, 1999