Synergistic interaction of T-786→C polymorphism in the endothelial nitric oxide synthase gene and smoking for an enhanced risk for coronary spasm

Pharmacogenetics

Volumn 13, Issue 11, 2003, Pages 683-688

  Nakayama, Masafumi ^a   Yoshimura, Michihiro ^a   Sakamoto, Tomohiro ^a   Shimasaki, Yukio ^a   Nakamura, Shota ^a   Ito, Teruhiko ^a   Abe, Koji ^a   Yamamuro, Megumi ^a   Miyamoto, Yoshihiro ^b   Saito, Yoshihiko ^c   Nakao, Kazuwa ^d   Yasue, Hirofumi ^e   Ogawa, Hisao ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

^b NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

^c NARA MEDICAL UNIVERSITY   (Japan)

^d KYOTO UNIVERSITY   (Japan)

^e Kumamoto Aging Research Institute   (Japan)

Author keywords

And smoking; Coronary spasm; Endothelial nitric oxide synthase; Polymorphism; T 786 C

Indexed keywords

ACETYLCHOLINE; ENDOTHELIAL NITRIC OXIDE SYNTHASE;

ADULT; ANGIOCARDIOGRAPHY; ARTICLE; CARDIOVASCULAR RISK; CONTROLLED STUDY; CORONARY ARTERY SPASM; DISEASE ASSOCIATION; EVALUATION; FEMALE; GENE INTERACTION; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RISK ASSESSMENT; SMOKING; THORAX PAIN;

ACETYLCHOLINE; AGED; ASIAN CONTINENTAL ANCESTRY GROUP; BASE SEQUENCE; CORONARY VASOSPASM; FEMALE; HUMANS; ISOSORBIDE DINITRATE; LOGISTIC MODELS; MALE; MIDDLE AGED; NITRIC OXIDE SYNTHASE; POLYMORPHISM, SINGLE NUCLEOTIDE; RETROSPECTIVE STUDIES; RISK FACTORS; SMOKING; VASODILATION; VASODILATOR AGENTS;

EID: 12144286056     PISSN: 0960314X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00008571-200311000-00004     Document Type: Article

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