The Effect of Endogenous Modulator Endobain E on NMDA Receptor Is Interfered by Zn 2+ but Is Independent of Modulation by Spermidine

Neurochemical Research

Volumn 29, Issue 4, 2004, Pages 819-825

  Reines A ^a,b   Zarate S ^a   Pena C ^b   Rodríguez De Lores Arnaiz, Georgina ^a,b  

^a Facultad de Medicina   (Argentina)

^b UNIVERSIDAD DE BUENOS AIRES   (Argentina)

Author keywords

Dizocilpine binding; Endobain; Endogenous modulator; NMDA receptor; Polyamine site; Receptor modulation; Spermidine; Zinc ion

Indexed keywords

ARCAINE; BLOCKING AGENT; DIZOCILPINE; ENDOBAIN E; GLUTAMIC ACID; GLYCINE; IFENPRODIL; MEMBRANE AFFECTING AGENT; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; POLYAMINE; REGULATOR PROTEIN; SPERMIDINE; UNCLASSIFIED DRUG; ZINC ION;

ANIMAL TISSUE; ARTICLE; BINDING COMPETITION; BINDING SITE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; IC 50; LIGAND BINDING; MALE; MEMBRANE BINDING; MEMBRANE CHANNEL; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR BINDING;

ANIMALS; DIZOCILPINE MALEATE; MALE; OUABAIN; RADIOLIGAND ASSAY; RATS; RATS, WISTAR; RECEPTORS, N-METHYL-D-ASPARTATE; SPERMIDINE; TRITIUM; ZINC;

ANIMALIA;

EID: 12144285998     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:NERE.0000018856.99773.71     Document Type: Article

References (30)

1. Dingledine, R., and McBain, C. J. 1999. Glutamate and aspartate. Pages 315-333, in Siegel, G. J., Agranoff, B. W., Albers, R. W., Fisher, S. K., and Uhler, M. D. (eds.), Basic Neurochemistry, 6th ed., Lippincott-Raven Press, Philadelphia.
2. Dingledine, R., Borges, K., Bowie, D., and Traynelis, S. F. 1999. The glutamate receptor ion channels. Pharmacol. Rev. 51:7-61.
3. Mothet, J. P., Parent, A. T., Wolosker, H., Brady, R. O. Jr., Linden, D. J., Ferris, C. D., Rogawski, M. A., and Snyder, S. H. 2000. D-Serine is an endogenous ligand for the glycine site of the N-methyl-D-aspartate receptor. Proc. Natl. Acad. Sci. USA 97:4926-4931.
4. Stone, T. W., and Addae, J. I. 2002. The pharmacological manipulation of glutamate receptors and neuroprotection. Eur. J. Pharmacol. 447:285-296.
5. Trombley, P. Q., and Shepherd, G. M. 1996. Differential modulation by zinc and copper of amino acid receptors from rat olfactory bulb neurons. J. Neurophysiol. 76:2536-2546.
6. 2+ binding to NMDA receptors. Neuron 25:683-694.
7. +-ATPase interaction with a brain endogenous inhibitor (endobain E). Neurochem. Int. 33:425-433.
8. +-ATPase inhibitor (endobain E) enhances norepinephrine release in rat hypothalamus. Neuroscience 90:573-579.
9. +-ATPase inhibitors. Neurochem. Int. 27:319-327.
10. +-ATPase inhibitor (endobain E) and ascorbic acid. Neurochem. Res. 28:903-910.
11. +-ATPase inhibitor: Comparison with ouabain. Neurochem. Int. 39:301-310.
12. +-ATPase inhibitor. J. Neurochem. 78:(Suppl. 1) BP18-BP44. (Abstract).
13. Ogita, K., and Yoneda, Y. 1999. Signal transduction through ion channels associated with excitatory amino acid receptors. Methods Enzymol. 294:385-410.
14. 3H](+)-5-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine (MK-801) binding in brain synaptic membranes treated with Triton X-100. J. Pharmacol. Exp. Ther. 256:1161-1172.
15. +-ATPase. Neurochem. Res. 11:933-947.
16. Cowburn, R. F., Wiehager, B., Trief, E., Li-Li, M., and Sundström, E. 1997. Effects of β-amyloid-(25-35) peptide on radioligand binding to excitatory amino acid receptor and voltage-dependent calcium channels: Evidence for a selective affinity for the glutamate and glycine recognition sites of NMDA receptor. Neurochem. Res. 22:1437-1442.
17. Lowry, O. H., Rosebrough, N. J., Farr, A. L., and Randall, R. J. 1951. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193:265-275.
18. Christine, C. W., and Choi, D. W. 1990. Effect of Zinc on NMDA receptor-mediated channel currents in cortical neurons. J. Neurosci. 10:108-116.
19. 3H]MK-801 binding to the N-methyl-D-aspartate receptor-ion channel complex by L-glutamate, glycine, and polyamines. J. Neurochem. 51:830-836.
20. Reynolds, I. J., and Miller, R. J. 1989. Ifenprodil is a novel type of N-Methyl-D-aspartate receptor antagonist: Interaction with polyamines. Mol. Pharmacol. 36:758-765.
21. Reynolds, I. J. 1990. Arcaine uncovers dual interaction of polyamines with the N-methyl-D-aspartate receptor. J. Pharmacol. Exp. Ther. 255:1001-1007.
22. 3H]N-(1-[thienyl]cyclohexyl)piperidine binding by arcaine: Evidence for a shared spermidine-magnesium binding site. Mol. Pharmacol. 38:705-710.
23. Donevan, S. D., Jones, S. M., and Rogawski, M. A. 1992. Arcaine blocks N-methyl-D-aspartate receptor responses by an open channel mechanism: Whole-cell and single-channel recording studies in cultured hippocampal neurons. Mol. Pharmacol. 41:727-735.
24. Rock, D. M., and MacDonald, R. L. 1992. Spermine and related polyamines produce a voltage-dependent reduction of N-methyl-D-aspartate receptor single-channel conductance. Mol. Pharmacol. 42:157-164.
25. Reynolds, I. J. 1992. 1,5-(Diethylamino)piperidine, a novel spermidine analogue that more specifically activates the N-methyl-D-aspartate receptor-associated polyamine site. Mol. Pharmacol. 41:989-992.
26. Bonhaus, D. W., and McNamara, J. O. 1988. N-methyl-D-aspartate receptor regulation of uncompetitive antagonist binding in rat brain membranes: Kinetic analysis. Mol. Pharmacol. 34:250-255.
27. Kloog, Y., Haring, R., and Sokolovsky, M. 1988. Kinetic characterization of the phencyclidine-N-methyl-D-aspartate receptor interaction: Evidence for a steric blockade of the channel. Biochemistry 27:843-848.
28. Reynolds, I. J., and Miller, R. J. 1988. Multiple sites for the regulation of the N-methyl-D-aspartate receptor. Mol. Pharmacol. 33:581-584.
29. 3H](±)-3-(2-carboxypiperazin-4-yl)phosphonic acid in brain synaptic membrane treated with Triton X-100. Biochem. Pharmacol. 39:225-228.
30. Williams, K., Dawson, V. L., Romano, C., Dichter, M. A., and Molinoff, P. B. 1990. Characterization of polyamines having agonist, antagonist and inverse agonist effect at the polyamine recognition site of the NMDA receptor. Neuron 5:199-208.