Drotrecogin alfa (activated) inhibits NF-kappa B activation and MIP-1-alpha release from isolated mononuclear cells of patients with severe sepsis

Inflammation Research

Volumn 53, Issue 10, 2004, Pages 528-533

  Brueckmann, M ^a   Hoffmann, U ^a   Dvortsak, E ^a   Lang, S ^a   Kaden, J J ^a   Borggrefe, M ^a   Haase, K K ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Drotrecogin alfa (activated); Factor kappa B; Mononuclear cells; Nuclear; rhAPC; Sepsis

Indexed keywords

DROTRECOGIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA;

ADULT; AGED; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BLOOD SAMPLING; CELL ISOLATION; CLINICAL ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DENSITY GRADIENT CENTRIFUGATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; HUMAN CELL; INHIBITION KINETICS; MALE; MONONUCLEAR CELL; PROTEIN SECRETION; SEPSIS; STATISTICAL SIGNIFICANCE;

ADULT; AGED; ANTI-INFECTIVE AGENTS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; LEUKOCYTES, MONONUCLEAR; MACROPHAGE INFLAMMATORY PROTEIN-1; MALE; MIDDLE AGED; NF-KAPPA B; PROTEIN C; RECOMBINANT PROTEINS; SEPSIS; TIME FACTORS;

EID: 12144259892     PISSN: 10233830     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00011-004-1291-z     Document Type: Article

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