Enhanced biotransformations and product recovery in a membrane bioreactor through application of a direct electric current

Biotechnology and Bioengineering

Volumn 89, Issue 1, 2005, Pages 18-23

  Mustacchi, Roberta ^a,b   Knowles, Christopher J ^a,b   Li, Hong ^a,b   Dalrymple, Ian ^c   Sunderland, Garry ^c   Skibar, Wolfgang ^c   Jackman, Simon A ^a,b  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b CENTRE FOR ECOLOGY AND HYDROLOGY   (United Kingdom)

^c C Tech Innovation Ltd   (United Kingdom)

Author keywords

Biotransformations; Direct current; Electrokinetics; In situ product recovery; Nitriles

Indexed keywords

AMMONIA; BENZENE; CATALYSIS; ELECTRIC CURRENTS; ENZYMES; MEMBRANES; NEGATIVE IONS; RATE CONSTANTS;

BENZOIC ACID; BENZONITRILE; BIOTRANSFORMATIONS;

BIOREACTORS;

AMMONIA; BENZOIC ACID; BENZONITRILE; NITRILASE;

ANION EXCHANGE; ARTICLE; BACTERIAL CELL; BIOREACTOR; BIOTRANSFORMATION; CATALYST; CHEMICAL REACTION; CONTROLLED STUDY; DIRECT CURRENT; ELECTRIC POTENTIAL; HYDROLYSIS; METABOLIC RATE; NONHUMAN; PRODUCT RECOVERY; PURIFICATION; REACTION TIME; REPRODUCIBILITY; RHODOCOCCUS; RHODOCOCCUS RHODOCHROUS; SEPARATION TECHNIQUE; TECHNIQUE;

AMINOHYDROLASES; BIOREACTORS; BIOTRANSFORMATION; ELECTRICITY; NITRILES; RHODOCOCCUS;

BACTERIA (MICROORGANISMS); RHODOCOCCUS; RHODOCOCCUS RHODOCHROUS;

EID: 12144253270     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/bit.20299     Document Type: Article

References (16)

1. Akerberg C, Zacchi G. 2000. An economic evaluation of the fermentative production of lactic acid from wheat flour. Bioresour Technol 75:119-126.
2. Bauchop TE. 1960. The growth of microorganisms in relation to their energy supply. J Gen Microbiol 23:457-469.
3. Chang Y-HD, Grodzinsky AJ, Wang DIC. 1995. Augmentation of mass transfer through electrical means for hydrogel-entrapped Escherichia coli cultivation. Biotechnol Bioeng 48:149-157.
4. Collins PA, Knowles CJ. 1983. The utilization of nitriles and amides by Nocardia rhodochrous. J Gen Microbiol 129:711-718.
5. Fowler J, Cohen L. 1993. Practical statistics for field biology. Chichester, UK: John Wiley & Sons.
6. Freeman A, Woodley JM, Lilly MD. 1983. In-situ product removal as a tool for bioprocessing. Bio-Technology 11:1007-1012.
7. Gehl J. 2003. Electroporation: theory and methods, perspectives for drug delivery, gene therapy and research. Acta Physiol Scand 177:437-447.
8. Jackman SA, Maini G, Sharman AK, Knowles CJ. 1999. The effects of direct electric current on the viability and metabolism of bacteria. Enzyme Microb Technol 24:316-324.
9. Jurado J, Bellhouse BJ. 1994. Application of electric-fields and vortex mixing for enhanced ultrafiltration. Filtr Separ 31:273-281.
10. Li H, Mustacchi R, Knowles CJ, Skibar W, Sunderland G, Dalrymple I, Jackman SA. 2004. An electrokinetic bioreactor: using direct electric current for enhanced lactic acid fermentation and product recovery. Tetrahedron 60:655-661.
11. Maini G, Sharman AK, Sunderland G, Knowles CJ, Jackman SA. 2000. An integrated method incorporating sulfur-oxidizing bacteria and electrokinetics to enhance removal of copper from contaminated soil. Environ Sci Technol 34:1081-1087.
12. Moresi M, Sappino F. 2000. Electrodialytic recovery of some fermentation products from model solutions: techno-economic feasibility study. J Membrane Sci 164:129-140.
13. Nagasawa T, Yamada H. 1989. Microbial transformation of nitriles. Trends Biotechnol 7:153-158.
14. Schmid A, Dordick JS, Hauer B, Kiener A, Wubbolts M, Witholt B. 2001. Industrial biocatalysis today and tomorrow. Nature 409:258-268.
15. Sunderland GJ, Knowles CJ, Li H, Mustacchi R, Jackman SA. 2002. Control of biccatalysis reactions. UK patent application no. 0227021.3.
16. Wouters PC, Smelt JPPM. 1997. Inactivation of microorganisms with pulsed electric fields: potential for food preservation. Food Biotechnol 11:193-229.