Performance of simultaneous and sequential Tc-99m/I-123 SPECT imaging in estimation of striatal activity

IEEE Nuclear Science Symposium Conference Record

Volumn 5, Issue , 2003, Pages 3134-3136

  Kijewski, M F ^a   El Fakhri, G ^a   Moore, S C ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN; COMPUTER SIMULATION; DISEASES; FUNCTIONS; MEDICAL IMAGING; MONTE CARLO METHODS; NEUROLOGY; SIGNAL TO NOISE RATIO;

ALZHEIMER'S DISEASE; PARKINSON'S DESEASE (PD); POINT-SPREAD FUNCTIONS (PSF); SNR;

COMPUTERIZED TOMOGRAPHY;

EID: 11944261248     PISSN: 10957863     EISSN: None     Source Type: Conference Proceeding    
DOI: None     Document Type: Conference Paper

References (12)

1. Asenbaum S, Brucke T, Pirker W, Podreka I, Angelberger P, Wenger S, et al. Imaging of dopamine transporters with iodine-123-b-CIT and SPECT in Parkinson's disease. J. Nucl. Med. 1997;38: 1-6.
2. Booij J, Winogrodzka RA, Bergmans P, Wolters EC, Stoof JC, Royen EA. [I-123]b-CIT and [I-123]FP-CIT SPECT are useful methods to monitor progression of dopaminergic degeneration in early-stage Parkinson's disease. J. Nucl. Med. 1999;40: 27P.
3. Seibyl JP, Innis RB, Early ML, Fussell BA, Marek K. Baseline striatal dopamine transporter uptake measured with [I-123] bCIT may predict the rate of disease progression in idiopathic Parkinson's disease. J. Nucl. Med. 1999; 40: 27P.
4. Fischman AJ, Bonab AA, Babich JW, Palmer EP, Alpert NM, Elmaleh DR, et al. Rapid detection of Parkinson's disease by SPECT with altropane: A selective ligand for dopamine transporters. Synapse 1998; 29: 128-141.
5. G. El Fakhri, P. Maksud, M. F. Kijewski, M. O. Habert, A. Todd-Pokropek, A. Aurengo, and S. C. Moore, "Scatter and cross-talk corrections in simultaneous Tc-99m/I-123 brain SPECT using constrained factor analysis and artificial neural networks," IEEE Transactions on Nuclear Science, vol. 47, pp. 1573-1580, 2000.
6. G. El Fakhri, S. C. Moore, P. Maksud, A. Aurengo, and M. F. Kijewski. Absolute activity quantitation in simultaneous I-123/Tc-99m brain SPECT. J. Nucl. Med. 2001, 42: 300,308.
7. Kung MP, Stevenson DA, Plossl K, Meegalla SK, Beckwith A, Essman WD, Mu M, Lucki I, and Kung HF, "[99m-Tc]TRODAT-1: a novel technetium-99m complex as a dopamine transporter imaging agent," Eur J Nucl Med, 1997;24: 372-380.
8. Verhoeff NP, Kapucu O, Sokole-Busemann E, van Royen E, Janssen AG. Estimation of dopamine D2 receptor binding potential in the striatum with Iodine-123-IBZM SPECT: technical and interobserver variability. J. Nucl. Med. 1993;34: 2076-2084.
9. Zubal IG, Harrell CR, Simth EO, Rattner Z, Gindi G, Hoffer PB. Computerized three-dimensional segmented human anatomy. Med. Phys. 1994;21:299-302.
10. Moore and El Fakhri. Realistic Monte Carlo simulation of Ga-67 SPECT imaging. IEEE Trans Nucl Sci, 2001; 48, pp. 720-724.
11. D. R. Haynor, R. L. Harrison, T. K. Lewellen. The use of importance sampling techniques to improve the efficiency of photon tracking in emission tomography simulations. Med. Phys. 1991, 18: 990-1001.
12. J. E. J. Dennis. Algorithm 573 NL2SOL - An adaptive least-squares algorithm [E4}. ACM Trans. Math. Software, 1981, 7: 369-383.