A comparison of the pharmacokinetics, clinical efficacy, and tolerability of once-daily tramadol tablets with normal release tramadol capsules

Journal of Pain and Symptom Management

Volumn 25, Issue 2, 2003, Pages 142-149

  Bodalia, Bhavesh ^a   McDonald, Chris J ^b   Smith, Kevin J ^b   O'Brien, Catherine ^b   Cousens, Lois ^b  

^a Gables Medicentre   (United Kingdom)

^b Napp Pharmaceuticals Limited   (United Kingdom)

Author keywords

Analgesia; Analgesics; Opioid; Osteoarthritis; Pharmacokinetics; Tramadol

Indexed keywords

TRAMADOL;

ADULT; ARTICLE; CAPSULE FILLING; CLINICAL ARTICLE; CLINICAL STUDY; CLINICAL TRIAL; COMPARATIVE STUDY; CONFIDENCE INTERVAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFICACY; DRUG FORMULATION; DRUG RELEASE; DRUG TOLERABILITY; FEMALE; HUMAN; MALE; OSTEOARTHRITIS; PAIN; PAIN ASSESSMENT; SCORING SYSTEM; SIDE EFFECT; TABLET;

ADULT; ANALGESICS, OPIOID; CAPSULES; CROSS-OVER STUDIES; DELAYED-ACTION PREPARATIONS; DOUBLE-BLIND METHOD; DRUG ADMINISTRATION SCHEDULE; FEMALE; HUMANS; MALE; OSTEOARTHRITIS; PALLIATIVE CARE; TABLETS; TRAMADOL;

EID: 0037313040     PISSN: 08853924     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0885-3924(02)00642-5     Document Type: Article

References (4)

1. Smith KJ, Miller AJ, Nichols TP, et al. Once-daily tramadol tablets: linear pharmacokinetics [abstract]. 9th World Congress on Pain in Vienna; 1999; Austria. Seattle: IASP Press, 336.
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3. Zech D., Radbruch L., Hertel D.et al. Slow release tramadol for chronic malignant pain - an open multicentre clinical trial. Br J Anaesth. 74(Suppl 1):1995;S144. [abstract].
4. Greenberg R.N. Overview of patient compliance with medication dosing. a literature review Clin Ther. 6:1984;592-599.