Hypoglycemia in stable, insulin-treated veterans with type 2 diabetes: A prospective study of 1662 episodes

Journal of Diabetes and its Complications

Volumn 19, Issue 1, 2005, Pages 10-17

  Murata, Glen H ^a,b   Duckworth, William C ^c,d   Shah, Jayendra H ^c,e   Wendel, Christopher S ^e   Mohler, M Jane ^c,e   Hoffman, Richard M ^a,b  

^a NEW MEXICO VA HEALTH CARE SYSTEM   (United States)

^b UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF ARIZONA   (United States)

^d CARL T HAYDEN VA MEDICAL CENTER   (United States)

^e SOUTHERN ARIZONA VA HEALTH CARE SYSTEM   (United States)

Author keywords

Hypoglycemia; Insulin; Type 2 diabetes

Indexed keywords

RECOMBINANT HUMAN INSULIN;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; EXERCISE; FEMALE; FOLLOW UP; FOOD INTAKE; GLUCOSE BLOOD LEVEL; HUMAN; HYPOGLYCEMIA; INFORMATION PROCESSING; LEARNING; MAJOR CLINICAL STUDY; MALE; MEDICAL DOCUMENTATION; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; SELF MONITORING; SOLDIER;

AGED; BLOOD GLUCOSE SELF-MONITORING; DIABETES MELLITUS, TYPE 2; FEMALE; FOLLOW-UP STUDIES; HUMANS; HYPOGLYCEMIA; HYPOGLYCEMIC AGENTS; INCIDENCE; INSULIN; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; RISK FACTORS; SELF ADMINISTRATION; VETERANS;

EID: 11844274699     PISSN: 10568727     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jdiacomp.2004.02.001     Document Type: Article

References (28)

1. Abraira C., Colwell J.A., Nuttall F.Q., Sawin C., Nagel N.J., Comstock J.P., Emanuele N.V., Levin S.R., Henderson W., Lee H.S. Veterans Affairs Cooperative Study on glycemic control and complications in type II diabetes (VA CSDM): results of the feasibility trial. Veterans Affairs Cooperative Study in type II diabetes. Diabetes Care. 18:1995;1113-1123
2. American Diabetes Association Tests of glycemia in diabetes. Diabetes Care. 27(Suppl. 1):2004;S91-S93
3. Burge M.R., Sobhy T.A., Qualls C.R., Schade D.S. Effect of short-term glucose control on glycemic thresholds for epinephrine and hypoglycemic symptoms. Journal of Clinical Endocrinology & Metabolism. 86:2001;5471-5478
4. Corsonello A., Pedone C., Corica F., Malara A., Carosella L., Sgadari A., Mauro V.N., Ceruso D., Pahor M., Carbonin P. Antihypertensive drug therapy and hypoglycemia in elderly diabetic patients treated with insulin and/or sulfonylureas. Gruppo Italiano di Farmacovigilanza nell'Anziano (GIFA). European Journal of Epidemiology. 15:1999;893-901
5. Cryer P.E. Hypoglycemia: the limiting factor in glycaemic management of type I and type II diabetes. Diabetologia. 45:2002;937-948
6. DeWitt D.E., Hirsch I.B. Outpatient insulin therapy in type 1 and type 2 diabetes mellitus. Scientific review. JAMA. 289:2003;2254-2264
7. Gürlek A., Erbas T., Gedik O. Frequency of severe hypoglycaemia in type 1 and type 2 diabetes during conventional insulin therapy. Experimental and Clinical Endocrinology & Diabetes. 107:1999;220-224
8. Harris M.I. Health care and health status and outcomes for patients with type 2 diabetes. Diabetes Care. 23:2000;754-758
9. Hart S.P., Frier B.M. Causes, management and morbidity of acute hypoglyaecemia in adults requiring hospital admission. QJM. 91:1998;505-510
10. Hepburn D.A., MacLeod K.M., Pell A.C., Scougal I.J., Frier B.M. Frequency and symptoms of hypoglycaemia experienced by patients with type 2 diabetes treated with insulin. Diabetic Medicine. 10:1993;231-237
11. Hoffman R.M., Shah J.H., Wendel C.S., Duckworth W.C., Adam K.D., Bokhari S.U., Dalton C., Murata G.H. Evaluating once- and twice-daily self-monitored blood glucose testing strategies for stable insulin-treated patients with type 2 diabetes: the Diabetes Outcomes in Veterans Study. Diabetes Care. 25:2002;1744-1748
12. Korzon-Burakowska A., Hopkins D., Matyka K., Lomas J., Pernet A., MacDonald I., Amiel S. Effects of glycemic control on protective responses against hypoglycemia in type 2 diabetes. Diabetes Care. 21:1998;283-290
13. MacLeod K.M., Hepburn D.A., Frier B.M. Frequency and morbidity of severe hypoglycaemia in insulin-treated diabetic patients. Diabetic Medicine. 10:1993;238-245
14. Meneilly G.S., Cheung E., Tuokko H. Counterregulatory hormone responses to hypoglycemia in the elderly patient with diabetes. Diabetes. 43:1994;403-410
15. Miller C.D., Phillips L.S., Ziemer D.C., Gallina D.L., Cook C.B., El-Kebbi I.M. Hypoglycemia in patients with type 2 diabetes mellitus. Archives of Internal Medicine. 161:2001;1653-1659
16. Murata G.H., Shah J.H., Adam K.D., Wendel C.S., Bokhari S.U., Solvas P.A., Hoffman R.M., Duckworth W.C. Factors affecting diabetes knowledge in type 2 diabetic veterans. Diabetologia. 46:2003;1170-1178
17. Murata G.H., Shah J.H., Wendel C.S., Hoffman R.M., Adam K.D., Bokhari S.U., Solvas P.A., Duckworth W.C. Risk factor management in stable, insulin-treated patients with type 2 diabetes. The Diabetes Outcomes in Veterans Study. Journal of Diabetes and Its Complications. 17:2003;186-191
18. Pegg A., Fitzgerald F., Wise D., Singh B.M., Wise P.H. A community-based study of diabetes-related skills and knowledge in elderly people with insulin-requiring diabetes. Diabetic Medicine. 8:1991;778-781
19. Saaddine J.B., Engelgau M.M., Beckles G.L., Gregg E.W., Thompson T.J., Narayan K.M. A diabetes report card for the United States: quality of care in the 1990s. Annals of Internal Medicine. 136:2002;565-574
20. Saudek C.D., Duckworth W.C., Giobbie-Hurder A., Henderson W.G., Henry R.R., Kelley D.E., Edelman S.V., Zieve F.J., Adler R.A., Anderson J.W., Anderson R.J., Hamilton B.P., Donner T.W., Kirkman M.S., Morgan N.A. Implantable insulin pump vs. multiple-dose insulin for non-insulin-dependent diabetes mellitus: a randomized clinical trial. Department of Veterans Affairs Implantable Insulin Pump Study Group. JAMA. 276:1996;1322-1327
21. Segel S.A., Paramore D.S., Cryer P.E. Hypoglycemia-associated autonomic failure in advanced type 2 diabetes. Diabetes. 51:2002;724-733
22. Spyer G., Hattersley A.T., MacDonald I.A., Amiel S., MacLeod K.M. Hypoglycaemic counter-regulation at normal blood glucose concentrations in patients with well controlled type-2 diabetes. Lancet. 356:2000;1970-1974
23. Stahl M., Berger W. Higher incidence of severe hypoglycaemia leading to hospital admission in type 2 diabetic patients treated with long-acting versus short-acting sulphonylureas. Diabetic Medicine. 16:1999;586-590
24. Stepka M., Rogala H., Czyzyk A. Hypoglycemia: a major problem in the management of diabetes in the elderly. Aging Clinical and Experimental Research (Milano). 5:1993;117-121
25. Sugarman J.R. Hypoglycemia associated hospitalizations in a population with a high prevalence of non-insulin-dependent diabetes mellitus. Diabetes Research and Clinical Practice. 14:1991;139-147
26. Thomson F.J., Masson E.A., Leeming J.T., Boulton A.J. Lack of knowledge of symptoms of hypoglycaemia by elderly diabetic patients. Age and Aging. 20:1991;404-406
27. United Kingdom Prospective Diabetes Study Research Group UK Prospective Study 24: a 6-year, randomized, controlled trial comparing sulfonylurea, insulin and metformin therapy in patients with newly diagnosed type 2 diabetes that could not be controlled with diet therapy. Annals of Internal Medicine. 128:1998;165-175
28. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). Lancet. 352:1998;837-853