Prevalence of katG Ser315 substitution and rpoB mutations in isoniazid-resistant Mycobacterium tuberculosis isolates from Brazil

International Journal of Tuberculosis and Lung Disease

Volumn 9, Issue 1, 2005, Pages 87-93

  Höfling, Christian Cruz ^a   Pavan, E M ^a   Giampaglia, C M S ^b   Ferrazoli, L ^b   Aily, D C G ^b   De Albuquerque, D M ^a   Ramos, M C ^a  

^a UNIVERSITY OF CAMPINAS   (Brazil)

^b INSTITUTO ADOLFO LUTZ   (Brazil)

Author keywords

Isoniazid; KatG; Resistance; RFLP; Rifampin; RpoB; Tuberculosis

Indexed keywords

ETHAMBUTOL; ISONIAZID; RIFAMPICIN; SERINE; STREPTOMYCIN; THREONINE; TUBERCULOSTATIC AGENT;

AMINO ACID SUBSTITUTION; ARTICLE; BACTERIAL GENE; BACTERIUM ISOLATION; BRAZIL; CODON; DRUG SENSITIVITY; EVALUATION; GENE MUTATION; GENE TARGETING; KATG GENE; MULTIDRUG RESISTANCE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PREVALENCE; PRIORITY JOURNAL; RPOB GENE; SENSITIVITY ANALYSIS; SEQUENCE ANALYSIS; SINGLE STRAND CONFORMATION POLYMORPHISM; STATISTICAL ANALYSIS; STRAIN IDENTIFICATION; TUBERCULOSIS;

ANTITUBERCULAR AGENTS; BACTERIAL PROTEINS; BRAZIL; CATALASE; DNA MUTATIONAL ANALYSIS; DNA-DIRECTED RNA POLYMERASES; DRUG RESISTANCE, MICROBIAL; HUMANS; ISONIAZID; MYCOBACTERIUM TUBERCULOSIS; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; PREVALENCE; RIFAMPIN; SEQUENCE ANALYSIS, DNA; TUBERCULOSIS, MULTIDRUG-RESISTANT;

EID: 11844271510     PISSN: 10273719     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (34)

1. World Health Organization. Report 2003, Global Tuberculosis Control. Geneva, Switzerland: WHO, 2003. [Online]. www.who.int/gtb/publications/globrep/ index.html
2. World Health Organization, The WHO/IUALTD Global Project on Anti-tuberculosis Drug Resistance Surveillance. Anti-tuberculosis Drug Resistance in the World. Report no. 2: Prevalence and Trends. Geneva, Switzerland: WHO, 2002. [Online], www.who.int/emc/amrtb.html
3. Centre de Vigilância Epidemiológica. Reports on chronic diseases: tuberculosis. Sao Paulo, Brazil: Centre de Vigilância Epidemiológica, 2002. [Online], www.cve.saude.sp.gov.br/htm/ Cve_tb.htm
4. Cohn D, Bustreo F, Ravioglione M C. Drug resistance in tuberculosis: review of the world-wide situation and WHO/IAUTLD global surveillance project. Clin Infect Dis 1997; 24 (Suppl 1): S121-S130.
5. Dye C, Espinal M A, Watt C J, Mbiaga C, Wiliams B G. Worldwide incidence of multidrug-resistant tuberculosis. J Infect Dis 2002; 185: 1197-1202
6. Altamirano M, Marostenmaki J, Wong A, Fitzgerald M, Black W A, Smith J A. Mutations in the catalase-peroxidase gene from isoniazid-resistant Mycobacterium tuberculosis isolates. J Infect Dis 1994; 169: 1162-1165.
7. Lee A S, Teo A S, Wong S Y. Novel mutations in ndh in isoniazid-resistant Mycobacterium tuberculosis isolates. Antimicrob Agents Chemother 2001; 45: 2157-2159.
8. Lee A S G, Lim I H K, Tang L L H, Telenti A, Wong S Y. Contribution of kasA analysis to detection of isoniazid-resistant Mycobacterium tuberculosis in Singapore. Antimicrob Agents Chemother 1999; 43: 2087-2089.
9. Ramaswamy S, Musser J M. Molecular genetic basis of antimicrobial resistance in Mycobacterium tuberculosis: 1998 Update. Tubercle Lung Dis 1998; 79: 3-29.
10. Abate G, Hoffner S E, Østergaard T V, Miörner H. Characterization of isoniazid-resistant strains of Mycobacterium tuberculosis on the basis of phenotypic properties and mutations in katG. Eur J Clin Microbiol Infect Dis 2001; 20: 329-333.
11. Mdluli K, Sherman D R, Hickey M J, et al. Biochemical and genetic data suggest that inhA is not the primary target for activated isoniazid in Mycobacterium tuberculosis. J Infect Dis 1996; 174: 1085-1090.
12. Mokrousov I, Narvskaya O, Often T, Limeschenko E, Steklova L, Vyshnevskiy B. High prevalence of katG Ser315Thr substitution among isoniazid-resistant Mycobacterium tuberculosis from Northwestern Russia, 1996 to 2001. Antimicrob Agents Chemother 2002; 46: 1417-1424
13. Musser J M, Kapur V, Williams D L, Kreiswirth B N, van Soolingen D, van Embden J D A. Characterization of the catalase-peroxidase gene (katG) and inhA. locus in isoniazid-resistant and -suceptible strains of Mycobacterium tuberculosis by automated DNA sequencing: restricted array of mutations associated with drug resistance. J Infect Dis 1996; 173: 196-202.
14. van Doom H R, Kuijper E J, van der Ende A, et al. The susceptibility of Mycobacterium tuberculosis to isoniazid and the Arg→Leu mutation at codon 463 of katG are not associated. J Clin Microbiol 2001; 39: 1591-1594.
15. van Soolingen D, Haas P E W, van Doom H R, Kuijper E, Rinder H, Borgdorff M W. Mutations at amino acid position 315 of the katG gene are associated with high-level resistance to isoniazid, other drug resistance, and successful transmission of Mycobacterium tuberculosis in The Netherlands. J Infect Dis 2000; 182: 1788-1790.
16. Rouse D A, De Vito J A, Li Z, Byer H, Morris S L. Site-directed mutagenesis of the katG gene of Mycobacterium tuberculosis: effects on catalase-peroxidase activities and isoniazid resistance. Mol Microbiol 1996; 22: 583-592.
17. Wengenack N L, Uhl J R, St Amand A L, et al. Recombinat Mycobacterium tuberculosis katG (S315T) is a competent catalase-peroxidase with reduced activity toward isoniazid. J Infect Dis 1997; 176: 722-727.
18. Silva M S, Senna S G, Ribeiro M O, et al. Mutations in katG, inhA, and ahpC genes of Brazilian isoniazid-resistant isolates of Mycobacterium tuberculosis. J Clin Microbiol 2003; 41: 4471-4474.
19. Telenti A, Imboden P, Marchesi E, Schmidheini T, Bodmer T. Direct, automated detection of rifampin-resistant Mycobacterium tuberculosis by polymerase chain reaction and single-strand conformation polymorphism analysis. Antimicrob Agents Chemother 1993; 37: 2054-2058.
20. Oliveira M M, da Silva, R A, Cardoso O M, et al. Rapid detection of resistance against rifampicin in isolates of Mycobacterium tuberculosis from Brazilian patients using a reverse-phase hybridisation assay. J Microbiol Methods 2003; 53: 335-342.
21. Spindola de Miranda S, Kritski A, Filiol I, Mabilat C, Panteix G, Drouet E. Mutations in the rpoB gene of rifampicin-resistant Mycobacterium tuberculosis strains isolated in Brazil and France. Mem Inst Oswalde Cruz 2001; 96: 247-250.
22. Valim A R, Rossetti M L R, Ribeiro M O, Zaha A. Mutations in the rpoB gene of multidrug-resistant Mycobacterium tuberculosis isolates from Brazil. J Clin Microbiol 2000; 38: 3119-3122.
23. Collins C H, Grange J M, Yates M D. Tuberculosis bacteriology, organization and pratice. 2nd ed. Oxford, UK: Butterworth-Heinemann, 1997: pp 98-109.
24. van Soolingen D, de Haas P E, Hermans P W, van Embden J D. DNA fingerprinting of Mycobacterium tuberculosis. Methods Enzymol 1994; 235: 196-205.
25. Rouse D A, Morris S L. Molecular mechanisms of resistance in Mycobacterium tuberculosis and Mycobacterium bovis. Infect Immun 1995; 63: 1427-1433.
26. Escalante P, Ramaswamy S, Sanabria H, et al. Genotypic characterization of drug-resistant Mycobacterium tuberculosis isolates from Peru. Tubercle Lung Dis 1998; 79: 111-118.
27. Bobadilla-del-Valle M, Ponce-de-Leon A, Arenas-Huertero C, et al. rpoB gene mutations in rifampicin-resistant Mycobacterium tuberculosis identified by polymerase chain reaction single-stranded conformation polymorfism. Emerg Infect Dis. 2001; 7: 1010-1013.
28. Altschul S F, Madden T L, Schaffer A A, et al. Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res 1997; 25: 3389-3402.
29. Ramaswamy S V, Reich R, Dou S J, et al. Single nucleotide polymorphisms in genes associated with isoniazid resistance in Mycobacterium tuberculosis. Antimicrob Agents Chemother 2003; 47: 1241-1250.
30. Kapur V, Li I, Iordanescu S, et al. Characterization by automated dna sequencing of mutations in the gene (rpob) encoding the rna polymerase beta subunit in rifampin-resistant Mycobacterium tuberculosis strains from New York City and Texas. J Clin Microbiol 1994; 32: 1095-1098.
31. Ahmad S, Fares E, Araj G F, Chugh T D, Mustafa A S. Prevalence of S315T mutation within the katG gene in isoniazid-resistant clinical Mycobacterium tuberculosis isolates from Dubai and Beirut. Int J Tuberc Lung Dis 2002; 6: 920-926.
32. Piatek A S, Telenti A, Murray M R, et al. Genotypic analysis of Mycobacterium tuberculosis in two distinct populations using molecular beacons: implications for rapid susceptibility testing. Antimicrob Agents Chemother 2000; 44: 103-110.
33. Tracevska T, Jansone I, Broka L, Marga O, Baumanis V. Mutations in the rpoB and katG genes leading to drug resistance in Mycobacterium tuberculosis in Latvia. J Clin Microbiol 2002; 40: 3789-3792.
34. Mani C, Selvakumaar N, Narayanan S, Narayanan P R. Mutations in the rpoB gene multidrug-resistant Mycobacterium tuberculosis clinical isolates from India. J Clin Microbiol 2001; 39: 2987-2990.