The midluteal decline in serum estradiol levels is drastic but not deleterious for implantation after in vitro fertilization and embryo transfer in patients with normal or high responses

Fertility and Sterility

Volumn 83, Issue 1, 2005, Pages 54-60

  Friedler, Shevach ^a,b   Zimerman, Ariel ^a   Schachter, Mori ^a   Raziel, Arieh ^a   Strassburger, Deborah ^a   Ron El, Raphael ^a  

^a TEL AVIV UNIVERSITY   (Israel)

^b ASSAF HAROFEH MEDICAL CENTER   (Israel)

Author keywords

E 2; implantation; IVF; Midluteal phase; pregnancy

Indexed keywords

ESTRADIOL;

ABORTION; ADULT; ARTICLE; BLOOD SAMPLING; CONCEPTION; CONTROLLED STUDY; CORRELATION ANALYSIS; EMBRYO; EMBRYO TRANSFER; FEMALE; FERTILIZATION IN VITRO; HEMOCONCENTRATION; HORMONE DETERMINATION; HUMAN; LUTEAL PHASE; MAJOR CLINICAL STUDY; OVARY HYPERSTIMULATION; PARAMETER; PATIENT SELECTION; PRIORITY JOURNAL; RETROSPECTIVE STUDY; STATISTICAL SIGNIFICANCE; UNIVERSITY HOSPITAL;

CHORIONIC GONADOTROPIN; EMBRYO IMPLANTATION; EMBRYO TRANSFER; ESTRADIOL; FEMALE; FERTILIZATION IN VITRO; HUMANS; LUTEAL PHASE; RETROSPECTIVE STUDIES;

EID: 11844269952     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2004.08.017     Document Type: Article

References (56)

1. R. Forman, N. Fries, J. Testart, J. Belaisch-Allart, A. Hazout, R. Frydman Evidence for an adverse effect of elevated serum estradiol concentration on embryo implantation Fertil Steril 49 1988 118 122
2. A. Pellicer, A. Ruiz, R.M. Castellvi, C. Calatayud, M. Ruiz, J.J. Tarin Is the retrieval of high numbers of oocytes desirable in patients treated with gonadotropin releasing hormone analogues (GnRHa) and gonadotropins? Hum Reprod 4 1989 536 540
3. A. Pellicer, D. Valbuena, F. Cano, J. Remohi, C. Simon Lower implantation rates in high responders: evidence for an altered endocrine milieu during the preimplantation period Fertil Steril 65 1996 1190 1195
4. J. Toner, R.G. Brzyski, S. Oehringer, L.L. Veeck, S. Simonetti, S.J. Muasher Combined impact of the number of pre-ovulatory oocytes and cryopreservation on in-vitro fertilization outcome Hum Reprod 6 1991 284 289
5. C. Simon, F. Cano, D. Valbuena, A. Remohi, A. Pellicer Clinical evidence for a detrimental effect on uterine receptivity of high serum estradiol levels in high and normal responder patients Hum Reprod 10 1995 2432 2434
6. C. Simon, J. Garcia-Velasco, D. Valbuena, J.A. Peinado, C. Moreno, J. Remohi Increasing uterine receptivity by decreasing estradiol levels during the preimplantation period in high responders with the use of a follicle-stimulating hormone step down regimen Fertil Steril 70 1998 234 239
7. F.I. Sharara, H.D. McClamrock High estradiol levels and high oocyte yield are not detrimental to in vitro fertilization outcome Fertil Steril 72 1999 401 405
8. F.I. Sharara, H.D. McClamrock Ratio of estradiol concentration on the day of human chorionic gonadotropin administration to mid-luteal oestradiol concentration is predictive of in-vitro fertilization outcome Hum Reprod 14 1999 2777 2782
9. J.H. Check, K. Nowroozi, J. Chase, A. Nazari, C. Braithwate Comparison of pregnancy rates, following in vitro fertilization-embryo transfer between donors and the recipients in a donor oocyte program J Assist Reprod Genet 9 1992 248 250
10. J.H. Check, J.K. Choe, D. Katsoff, D. Summers-Chase, C. Wilson Controlled ovarian hyperstimulation adversely impacts implantation following in vitro fertilization embryo transfer J Assist Reprod Genet 16 1999 416 420
11. P.E. Chenette, M.V. Sauer, R.J. Paulson Very high serum estradiol levels are not detrimental to clinical outcome of in vitro fertilization Fertil Steril 54 1990 858 863
12. E.H.Y. Ng, W.S.B. Yeung, E.Y.L. Lau, W.W.K. So, P.C. Ho High serum estradiol concentration in fresh IVF cycles do not impair implantation and pregnancy rates in subsequent frozen thawed embryo transfer cycles Hum Reprod 15 2000 250 255
13. E.H.Y. Ng, W.S.B. Yeung, E.Y.L. Lau, W.W.K. So, P.C. Ho A rapid decline in serum estradiol concentrations around the mid-luteal phase had no adverse effect on outcome in 763 assisted reproduction cycles Hum Reprod 15 2000 1903 1908
14. A. Levi, M. Drews, P.A. Bergh, B.T. Miller, R.T. Scott Controlled ovarian hyperstimulation does not adversely affect endometrial receptivity in in vitro fertilization cycles Fertil Steril 76 2002 670 674
15. J. Smith, G. Oskowitz Abbott AxSYM random and continuous access immunoassay system for improved workflow in the clinical laboratory Clin Chem 39 1993 2063 2069
16. M.H. Zweig, G. Cambell Receiver operating characteristic (ROC) plots: a fundamental evaluation tool in clinical medicine Clin Chem 39 1993 561 577
17. D. de Ziegler Hormonal control of endometrial receptivity Hum Reprod 10 1995 4 7
18. D. Ghosh, J. Senupta Another look at the issue of peri-implantation oestrogen Hum Reprod 10 1995 1 2
19. D.H. Edgar Oestrogen and human implantation Hum Reprod 10 1995 2 4
20. E. Kapetanakis, K.J. Pantos Continuation of a donor oocyte pregnancy in menopause without early pregnancy support Fertil Steril 54 1990 1171 1173
21. J.P. Stassart, R.S. Corfman, G.D. Ball Continuation of a donor oocyte pregnancy in a functionally agonadal patient without early oestrogen support Hum Reprod 10 1995 3061 3063
22. F. Zegers-Hochschild, E. Altieri Luteal estrogen is not required for the establishment of pregnancy in the human J Assist Reprod Genet 12 1995 224 228
23. D. de Ziegler, C. Bergeron, C. Cornel, D.A. Medalie, M.R. Massai, E. Milgrom Effects of luteal oestradiol on the secretory transformation of human endometrium and plasma gonadotropins J Clin Endocrinol Metab 74 1992 322 331
24. J.S. Younis, Y. Ezra, Y. Sherman, A. Simon, J.G. Schenker, N. Laufer The effect of estradiol depletion during the luteal phase on endometrial development Fertil Steril 62 1994 103 107
25. A.A. Gidley-Baird, C. O'Neil, M.J. Sinosich, R.N. Porter, I.L. Pike, D.M. Saunders Failure of implantation in human in vitro fertilization and embryo transfer patients: the effects of altered progesterone/estradiol ratios in humans and mice Fertil Steril 45 1986 69 75
26. G.T. Fossum, A. Davidson, R.J. Paulson Ovarian hyperstimulation inhibits embryo implantation in the mouse J In Vitro Fertil Embryo Transfer 6 1998 7 10
27. R.J. Paulson, M.V. Sauer, R.A. Lobo Embryo implantation after human in vitro fertilization: importance of endometrial receptivity Fertil Steril 53 1990 870 874
28. A.M. Aboulghar, R.T. Mansour, G.I. Serour, A.M. Ramzy, Y.M. Amin Oocyte quality in patients with severe ovarian hyperstimulation syndrome Fertil Steril 68 1997 1017 1021
29. A. Raziel, S. Friedler, M. Schachter, D. Strassburger, E. Mordehai, R. Ron-El Increased early pregnancy loss in IVF patients with severe ovarian hyperstimulation syndrome Hum Reprod 17 2002 107 110
30. J.E. Pena, P.L. Chang, L.K. Chan, K. Zeitoun, M.H. Thornton, M.V. Sauer Supraphysiological estradiol levels do not affect oocyte and embryo quality in oocyte donation cycles Hum Reprod 17 2002 83 87
31. M.E. Schalkoff, S.P. Oskowitz, R.D. Powers A multifactorial analysis of the pregnancy outcome in a successful embryo cryopreservation program Fertil Steril 59 1993 1070 1074
32. D. Valbuena, J. Martin, J.L. De Pablo, J. Remohi, A. Pellicer, C. Simon Increasing levels of estradiol are deleterious to embryonic implantation because they directly affect the embryo Fertil Steril 76 2001 962 968
33. J.E. Garcia, A.A. Acosta, J.G. Hsiu, H.W. Jones Jr Advanced endometrial maturation after ovulation induction with human menopausal gonadotropin/human chorionic gonadotropin for in vitro fertilization Fertil Steril 41 1984 31 37
34. D. Martel, R. Frydman, M. Glissant, C. Maggioni, D. Roche, A. Psychoyos Scanning electron microscopy of postovulatory human endometrium in spontaneous cycles and cycles stimulated by hormone treatment J Endocrinol 114 1987 319 324
35. A. Bonhoff, E. Johannisson, H.G. Bohnet Morphometric analysis of the endometrium of infertile patients in relation to peripheral hormone levels Fertil Steril 54 1990 84 89
36. E. Cittadini, R. Palermo The endometrium in human assisted reproduction Ann N Y Acad Sci 622 1991 230 235
37. C.A. Benadiva, D.A. Metzger Superovulation with human menopausal gonadotropins is associated with endometrial gland-stroma dyssynchrony Fertil Steril 61 1994 700 704
38. I. Noci, P. Borri, M.E. Coccia, L. Criscuoli, G. Scarselli, G. Messeri Hormonal patterns, steroid receptors and morphological pictures of endometrium in hyperstimulated IVF cycles Eur J Obstet Gynecol Reprod Biol 75 1997 215 220
39. B.A. Kolb, S. Najmabadi, R.J. Paulson Ultrastructural characteristics of the luteal phase endometrium in patients undergoing controlled ovarian hyperstimulation Fertil Steril 67 1997 625 630
40. F.H. Hadi, E. Chantler, E. Anderson, R. Nicholson, R.A. McClelland, M.W. Seif Ovulation induction and endometrial steroid receptors Hum Reprod 9 1994 2405 2410
41. P.J. Macrow, T.C. Li, M.W. Seif, C.H. Buckley, M. Elstein Endometrial structure after superovulation: a prospective controlled study Fertil Steril 61 1994 696 699
42. A.J. Castelbaum, J. Wheeler, C. Coutifaris, L. Mastroianni Jr, B.A. Lessey Timing of the endometrial biopsy may be critical for the accurate diagnosis of luteal phase deficiency Fertil Steril 8 1993 1 5
43. N. Laufer, D. Navot, J.G. Schenker The pattern of luteal phase plasma progesterone and estradiol in fertile couples Am J Obstet Gynecol 143 1981 808 813
44. S.J. Muasher, A.A. Acosta, J. Garcia, G.S. Jones, H.W. Jones Jr Luteal phase serum estradiol and progesterone in in vitro fertilization Fertil Steril 41 1984 838 843
45. L. Mettler, H.W. Michelmann Estradiol values under gonadotropin stimulation in relation to the outcome of pregnancies in in vitro fertilization and embryo transfer J In Vitro Fertil Embryo Transfer 4 1987 303 306
46. L. Nylund, C. Beskow, K. Carlstrom, B. Fredricsson, O. Gustafson, N.O. Lunell The early luteal phase in successful and unsuccessful implantation after IVF-embryo transfer Hum Reprod 5 1990 40 42
47. D.R. Stewart, J.W. Overstreet, S.T. Nakajima, B.L. Lasley Enhanced ovarian steroid secretion before implantation in early human pregnancy J Clin Endocrinol Metab 76 1993 1470 1476
48. K.A. Hutchinson-Williams, B. Lunenfeld, M.P. Diamond, G. Lavy, S.P. Boyers, A.H. De Cherney Human chorionic gonadotropin, estradiol and progesterone profiles in conception and non-conception cycles in an in vitro fertilization program Fertil Steril 52 1989 441 445
49. M.A. Akman, H.F. Erden, F. Bener, J.E. Liu, M. Bahceci Can luteal phase estradiol levels predict the pregnancy outcome in in vitro fertilization cycles of good responders whose excess embryos yield blastocysts? Fertil Steril 77 2002 638 639
50. J. Smitz, C. Bourgain, L. Van Waesberghe, M. Camus, P. Devroey, A.C. Van Steirteghem A prospective randomized study on oestradiol valerate supplementation in addition to intravaginal micronized progesterone in buserelin and HMG induced superovulation Hum Reprod 8 1993 40 45
51. A. Lewin, A. Benshusan, E. Mezker, N. Yanai, J.G. Schenker, R. Goshen The role of estrogen support during the luteal phase in in vitro fertilization-embryo transplant cycles: a comparative study between progesterone alone and estrogen and progesterone support Fertil Steril 62 1994 121 125
52. A. Herman, A. Raziel, D. Strassburger, Y. Soffer, I. Bukovsky, R. Ron-El The benefits of mid-luteal addition of human chorionic gonadotropin in in-vitro fertilization using a down regulation protocol and luteal support with progesterone Hum Reprod 11 1996 1552 1557
53. J. Farhi, A. Weissman, Z. Steinfeld, M. Shorer, H. Nahum, D. Levran Estradiol supplementation during the luteal phase may improve the pregnancy rate in patients undergoing in vitro fertilization-embryo transfer cycles Fertil Steril 73 2000 761 766
54. J. Smitz, P. Devroey, P. Braeckmans, M. Camus, I. Khan, C. Staessen Management of failed cycles in an IVF/GIFT programme with the combination of a GNRH analogue and hMG Hum Reprod 2 1987 309 314
55. J. Smitz, P. Devroey, M. Camus, J. Deschacht, I. Khan, C. Staessen The luteal phase and early pregnancy after combined GNRH-agonist/hMG treatment for superovulation in IVF or GIFT Hum Reprod 3 1988 585 590
56. V. Nikkanen, I. Kresanov, J. Makinen, T. Vuorento The effect of luteal support with human chorionic gonadotropin or progesterone on the daily progesterone profile after different types of ovarian stimulation Hum Reprod 7 1992 333 336