Effect of Helicobacter pylori VacA on gene expression of gastric cancer cells

World Journal of Gastroenterology

Volumn 11, Issue 1, 2005, Pages 109-113

  Wang, Hong Tao ^a   Li, Zhen Hong ^a   Yuan, Jian Ping ^a   Zhao, Wei ^a   Shi, Xiao Dong ^a   Tong, Shan Qing ^a   Guo, Xiao Kui ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Gastric cancer; Helicobacter pylori; VacA gene

Indexed keywords

TUMOR PROMOTER; VACUOLATING TOXIN;

APOPTOSIS; ARTICLE; BACTERIAL STRAIN; BACTERIAL VIRULENCE; CANCER CELL CULTURE; CANCER GROWTH; CELL CYCLE; CELL STRUCTURE; CONCENTRATION RESPONSE; CONFOCAL MICROSCOPY; CYTOSKELETON; DNA MICROARRAY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE MUTATION; HELA CELL; HELICOBACTER PYLORI; HUMAN; HUMAN CELL; INFLAMMATION; MICROTUBULE ASSEMBLY; MOLECULAR CLONING; SIGNAL TRANSDUCTION; STOMACH CANCER; TUMOR SUPPRESSOR GENE;

EID: 11844256925     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v11.i1.109     Document Type: Article

References (32)

1. Ogura K, Maeda S, Nakao M, Watanabe T, Tada M, Kyutoku T, Yoshida H, Shiratori Y, Omata M. Virulence factors of Helicobacter pylori responsible for gastric diseases in Mongolian gerbil. J Exp Med 2000; 192: 1601-1610
2. Leunk RD, Johnson PT, David BC, Kraft WG, Morgan DR. Cytotoxic activity in broth-culture filtrates of Campylobacter pylori. J Med Microbiol 1988; 26: 93-99
3. Sepulveda AR. Molecular testing of Helicobacter pylori-associated chronic gastritis and premalignant gastric lesions: clinical implication. J Clin Gastroenterol 2001; 32: 377-382
4. Mann NS, Westblom TU. Helicobacter pylori and the future: an afterword. Curr Top Microbiol Immunol 1999; 241: 301-308
5. Ogura K, Takahashi M, Maeda S, Ikenoue T, Kanai F, Yoshida H, Shiratori Y, Mori K, Mafune KI, Omata M. Interleukin-8 production in primary cultures of human gastric epithelial cells induced by Helicobater pylori. Dig Dis Sci 1998; 43: 2738-2743
6. Wagner S, Beil W, Westermann J, Logan RP, Bock CT, Trautwein C, Bleck JS, Manns MP. Regulation of gastric epithelial cell growth by Helicobacter pylori: offdence for a major role of apoptosis. Gastroenterology 1997; 113: 1836-1847
7. Cover TL, Halter SA, Blaser MJ. Characterization of HeLa cell vacuoles induced by Helicobacter pylori broth culture supernatant. Hum Pathol 1992; 23: 1004-1010
8. Segal ED, Falkow S, Tompkins LS. Helicobacter pylori attachment to gastric cells induces cytoskeletal rearrangements and tyrosine phosphorylation of host cell proteins. Proc Natl Acad Sci USA 1996; 93: 1259-1264
9. Cox JM, Clayton CL, Tomita T, Wallace DM, Robinson PA, Crabtree JE. cDNA array analysis of cag pathogenicity island-associated Helicobacter pylori epithelial cell response genes. Infect Immun 2001; 69: 6970-6980
10. Chiou CC, Chan CC, Sheu DL, Chen KT, Li YS, Chan EC. Helicobacter pylori infection induced alteration of gene expression in human gastric cells. Gut 2001; 48: 598-604
11. Maeda S, Otsuka M, Hirata Y, Mitsuno Y, Yoshida H, Shiratori Y, Masuho Y, Muramatsu M, Seki N, Omata M. cDNA microarray analysis of Helicobacter pylori-mediated alteration of gene expression in gastric cancer cells. Biochem Biophys Res Commun 2001; 284: 443-449
12. Chang K, Fujiwara Y, Wyle F, Tarnawski A. Helicobacter pylori toxin inhibits growth and proliferation of cultured gastric cells-kato III. J Physiol Pharmacol 1993; 44 17-22
13. Fujiwara Y, Wyle F, Arakawa T, Domek MJ, Fukuda T, Kobayashi K, Tarnawski A. Helicobacter pylori culture supernatant inhibits binding and proliferative response of human gastric cells to epidermal growth factor: Implications for H pylori interference with ulcer healing? Digestion 1997; 58: 299-303
14. Pai R, Cover TI, Tarnawski AS. Helicobacter pylori vacuolating cytotoxin (VacA) disorganizes the cytoskeletal architecture of gastric epithelial cells. Biochem Biophys Res Commun 1999; 262: 245-250
15. Ashorn M, Cantet F, Mayo K, Megraud F. Cytoskeletal rearrangements induced by Helicobacter pylori strains in epithelial cell culture: possible role of the cytotoxin. Dig Dis Sci 2000; 45: 1774-1780
16. Henics T, Wheatley DN. Vacuolar cytoplasmic phase separation in cultured mammalian cells involves the microfilament network and reduces motional properties of intracellular water. Int J Exp Pathol 1997; 78: 343-354
17. Henics T, Wheatley DN. Cytoplasmic vacuolation, adaptation and cell death: a view on new perspectives and features. Biol Cell 1999; 91: 485-498
18. Pai R, Sasaki E, Tarnawski AS. Helicobacter pylori vacuolating cytotoxin (VacA) alters cytoskeleton-associated proteins and interferes with re-epithelialization of wounded gastric epithelial monolayers. Cell Biol Int 2000; 24: 291-301
19. Humphries CL, Balcer HI, D'Agostino JL, Winsor B, Drubin DG, Barnes G, Andrews BJ, Goode BL. Direct regulation of Arp2/3 complex activity and function by the actin binding protein coronin. J Cell Biol 2002; 159: 993-1004
20. Poon E, Howman EV, Newey SE, Davies KE. Association of syncoilin and desmin: Linking intermediate filament proteins to the dystrophin-associated protein complex. J Biol Chem 2002; 277: 3433-3439
21. Deacon SW, Serpinskaya AS, Vaughan PS, Lopez Fanarraga M, Vernos I, Vaughan KT, Gelfand VI. Dynactin is required for bidirectional organelle transport. J Cell Biol 2003; 160: 297-301
22. IARC working group on the evaluation of carcinogenic risks to humans: some industrial chemicals. Lyon, 15-22 February 1994. IARC Monogr Eval Carcinog Risks Hum 1994; 60: 1-560
23. Park JH, Lee SW. Hypertonicity induction of melanoma antigen, a tumor-associated antigen. Mol Cells 2002; 13: 288-295
24. Kavalar R, Sarcevic B, Spagnoli GC, Separovic V, Samija M, Terracciano L, Heberer M, Juretic A. Expression of MAGE tumour-associated antigens is inversely correlated with tumour differentiation in invasive ductal breast cancers: an immunohistochemical study. Virchows Arch 2001; 439: 127-131
25. Yang DH, Smith ER, Cohen C, Wu H, Patriotis C, Godwin AK, Hamilton TC, Xu XX. Molecular events associated with dysplastic morphologic transformation and initiation of ovarian tumorigenicity. Cancer 2002; 94: 2380-2392
26. Liu SH, Lin CY, Peng SY, Jeng YM, Pan HW, Lai PL, Liu CL, Hsu HC. Down-regulation of annexin A10 in hepatocellular carcinoma is associated with vascular invasion, early recurrence, and poor prognosis in synergy with p53 mutation. Am J Pathol 2002; 160: 1831-1837
27. Hiyama E, Hiyama K. Telomerase as tumor marker. Cancer Lett 2003; 194: 221-233
28. Bukau B, Horwich AL. The Hsp70 and Hsp60 chaperone machines. Cell 1998; 92: 351-366
29. Sherman MY, Goldberg AL. Cellular defenses against unfolded proteins: A cell biologist thinks about neurodegenerative diseases. Neuron 2001; 29: 15-32
30. Falkowska-Podstawka M, Wernicki A. Heat shock proteins in health and disease. Pol J Vet Sci 2003; 6: 61-70
31. Hichey E, Brandon SE, Smale G, Lloyd D, Weber LA. Sequence and regulation of a gene encoding a human 89-kilodalton heat shock protein. Mol Cell Biol 1989; 9: 2615-2626
32. Ambrus JL Jr, Fauci AS. Human B lymphoma cell line producing B cell growth factor. J Clin Invest 1985; 75: 732-739