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1
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0025845185
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H. Kigoshi, H. Niwa, K. Yamada, T. J. Stout, and J. Clardy, Tetrahedron Lett., 32, 2427 (1991).
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Kigoshi, H.1
Niwa, H.2
Yamada, K.3
Stout, T.J.4
Clardy, J.5
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2
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11844278161
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note
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This sponge was identified as a new species in Spongia by Professor Patricia R. Bergquist, the University of Auckland.
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3
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11844291882
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note
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-1.
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4
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2142858450
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I. Ohtani, T. Kusumi, Y. Kashman, and H. Kakisawa, J. Am. Chem. Soc., 113, 4092 (1991).
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Ohtani, I.1
Kusumi, T.2
Kashman, Y.3
Kakisawa, H.4
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5
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0343314897
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A. Fontana, M. C. Gonzalez, M. Gavagnin, J. Templado, and G. Cimino, Tetrahedron Lett., 41, 429 (2000).
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Fontana, A.1
Gonzalez, M.C.2
Gavagnin, M.3
Templado, J.4
Cimino, G.5
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6
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0028332522
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In the modified Mosher's method, the effects of a MTPA ester were thought to appear more strongly at the γ- and ε-hydrogens than at the β- and δ-hydrogens in acyclic compounds. In spongiacysteine (1), we could conclude that H-4 was strongly influenced by the MTPA ester at C-2. On the other hand, H-3 was influenced by the MTPA ester at C-5. The positional differences of the effect of the MTPA group are found in many literatures. See: T. Kusumi, T. Ooi, and H. Uchimura, Tetrahedron Lett., 35, 3127 (1994); T. Kusumi, H. Takahashi, P. Xu, T. Fukushima, Y. Asakawa, T. Hashimoto, Y. Kan, and Y. Inouye, Tetrahedron Lett., 35, 4397 (1994); K. Kouda, T. Ooi, and T. Kusumi, Tetrahedron Lett., 40, 3005 (1999).
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Tetrahedron Lett.
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Kusumi, T.1
Ooi, T.2
Uchimura, H.3
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7
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0028263417
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In the modified Mosher's method, the effects of a MTPA ester were thought to appear more strongly at the γ- and ε-hydrogens than at the β- and δ-hydrogens in acyclic compounds. In spongiacysteine (1), we could conclude that H-4 was strongly influenced by the MTPA ester at C-2. On the other hand, H-3 was influenced by the MTPA ester at C-5. The positional differences of the effect of the MTPA group are found in many literatures. See: T. Kusumi, T. Ooi, and H. Uchimura, Tetrahedron Lett., 35, 3127 (1994); T. Kusumi, H. Takahashi, P. Xu, T. Fukushima, Y. Asakawa, T. Hashimoto, Y. Kan, and Y. Inouye, Tetrahedron Lett., 35, 4397 (1994); K. Kouda, T. Ooi, and T. Kusumi, Tetrahedron Lett., 40, 3005 (1999).
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Tetrahedron Lett.
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, pp. 4397
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Kusumi, T.1
Takahashi, H.2
Xu, P.3
Fukushima, T.4
Asakawa, Y.5
Hashimoto, T.6
Kan, Y.7
Inouye, Y.8
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8
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0033537913
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In the modified Mosher's method, the effects of a MTPA ester were thought to appear more strongly at the γ- and ε-hydrogens than at the β- and δ-hydrogens in acyclic compounds. In spongiacysteine (1), we could conclude that H-4 was strongly influenced by the MTPA ester at C-2. On the other hand, H-3 was influenced by the MTPA ester at C-5. The positional differences of the effect of the MTPA group are found in many literatures. See: T. Kusumi, T. Ooi, and H. Uchimura, Tetrahedron Lett., 35, 3127 (1994); T. Kusumi, H. Takahashi, P. Xu, T. Fukushima, Y. Asakawa, T. Hashimoto, Y. Kan, and Y. Inouye, Tetrahedron Lett., 35, 4397 (1994); K. Kouda, T. Ooi, and T. Kusumi, Tetrahedron Lett., 40, 3005 (1999).
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, vol.40
, pp. 3005
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Kouda, K.1
Ooi, T.2
Kusumi, T.3
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9
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0025208306
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a) M. Hikota, H. Tone, K. Horita, and O. Yonemitsu, J. Org. Chem., 55, 7 (1990).
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Hikota, M.1
Tone, H.2
Horita, K.3
Yonemitsu, O.4
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10
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0001616071
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b) J. Inanaga, K. Hirata, H. Saeki, T. Katsuki, and M. Yamaguchi, Bull. Chem. Soc. Jpn., 52, 1989 (1979).
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Inanaga, J.1
Hirata, K.2
Saeki, H.3
Katsuki, T.4
Yamaguchi, M.5
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11
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11844251099
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note
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3, 3H), 2.72 (dd, J = 2.6, 15.3 Hz, H-3′β, 1H), 2.28 (dd, J = 6.9, 14.8 Hz, H-2″α, 1H), 2.22 (dd, J = 6.8, 14.8 Hz, H-2″β, 1H), 2.17 (m, H-3″, 1H), 1.65-1.20 (m, H-4, H-6, H-7, 6H), 1.45 (d, J = 6.3 Hz, H-1, 3H), 0.98 (d, J = 6.4 Hz, H-4″, 3H), 0.97 (d, J = 6.4 Hz, H-5″, 3H), 0.93 (t, J = 7.1 Hz, H-8, 3H).
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12
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84984088842
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W. Keller-Schierlein, M. L. Mihailovie, and V. Prelog, Helv. Chim. Acta, 26, 305 (1959).
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Keller-Schierlein, W.1
Mihailovie, M.L.2
Prelog, V.3
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13
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0030860279
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a) M. Tokunaga, J. F. Larrow, F. Kakiuchi, and E. N. Jacobsen, Science, 227, 936 (1997).
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Tokunaga, M.1
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Jacobsen, E.N.4
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14
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0037138704
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b) S. E. Schaus, B. D. Brandes, J. F. Larrow, M. Tokunaga, K. B. Hansen, A. E. Gould, M. E. Furrow, and E. N. Jacobsen, J. Am. Chem. Soc., 124, 1307 (2002).
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Schaus, S.E.1
Brandes, B.D.2
Larrow, J.F.3
Tokunaga, M.4
Hansen, K.B.5
Gould, A.E.6
Furrow, M.E.7
Jacobsen, E.N.8
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15
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33845557675
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E. D. Mihelich, K. Daniels, and D. J. Eickhoff, J. Am. Chem. Soc., 103, 7690 (1981).
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Mihelich, E.D.1
Daniels, K.2
Eickhoff, D.J.3
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16
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11844296603
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note
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D -115 (c 0.02, MeOH). The difference in the values between the natural and synthetic samples may be due to an error in the measurement of the natural specimen due to lack of the sample.
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17
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84873779431
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T. Ishiyama, I. Hara, M. Matsuoka, K. Sato, S. Shimada, R. Izawa, T. Hashimoto, M. Hamada, Y. Okami, T. Takeuchi, and H. Umezawa, J. Antibiot., Ser. A, 18, 115 (1965).
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Ishiyama, T.1
Hara, I.2
Matsuoka, M.3
Sato, K.4
Shimada, S.5
Izawa, R.6
Hashimoto, T.7
Hamada, M.8
Okami, Y.9
Takeuchi, T.10
Umezawa, H.11
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