-
1
-
-
2642709177
-
Declining morbidity and mortality among patients with advanced HIV infection
-
HIV outpatient study investigators
-
Palella FR Jr, Delaney KM, Moorman AC, et al. Declining morbidity and mortality among patients with advanced HIV infection. HIV outpatient study investigators. N Engl J Med 1998;338:856-60.
-
(1998)
N Engl J Med
, vol.338
, pp. 856-860
-
-
Palella Jr., F.R.1
Delaney, K.M.2
Moorman, A.C.3
-
2
-
-
0037192573
-
Determinants of recurrent toxicity-driven switches of highly active antiretroviral therapy. The Athena cohort
-
Dieleman JP, Jambroes M, Gyssens IG, et al. Determinants of recurrent toxicity-driven switches of highly active antiretroviral therapy. The Athena cohort. AIDS 2002;16:737-45.
-
(2002)
AIDS
, vol.16
, pp. 737-745
-
-
Dieleman, J.P.1
Jambroes, M.2
Gyssens, I.G.3
-
3
-
-
0037055025
-
Antiretroviral treatment for adult HIV infection in 2002
-
Yeni PG, Hammer SM, Cooper DA, et al. Antiretroviral treatment for adult HIV infection in 2002. JAMA 2002;288:222-35.
-
(2002)
JAMA
, vol.288
, pp. 222-235
-
-
Yeni, P.G.1
Hammer, S.M.2
Cooper, D.A.3
-
4
-
-
0036840147
-
Management of metabolic complications associated with antiretroviral therapy for HIV-1 infection: Recommendations of an International AIDS Society-USA panel
-
Schambelan M, Benson CA, Carr A. Management of metabolic complications associated with antiretroviral therapy for HIV-1 infection: recommendations of an International AIDS Society-USA panel. J Acquir Immune Defic Syndr 2002;31(3):257-75.
-
(2002)
J Acquir Immune Defic Syndr
, vol.31
, Issue.3
, pp. 257-275
-
-
Schambelan, M.1
Benson, C.A.2
Carr, A.3
-
5
-
-
0037043652
-
Antiretroviral-drug resistance among patients recently infected with HIV
-
Little SJ, Holte S, Routy JP, et al. Antiretroviral-drug resistance among patients recently infected with HIV. N Engl J Med 2002;347:385-94.
-
(2002)
N Engl J Med
, vol.347
, pp. 385-394
-
-
Little, S.J.1
Holte, S.2
Routy, J.P.3
-
6
-
-
0037055016
-
Time trends in primary HIV-drug resistance among recently infected persons
-
Grant RM, Hecht FM, Warmerdam M, et al. Time trends in primary HIV-drug resistance among recently infected persons. JAMA 2002;288:181-8.
-
(2002)
JAMA
, vol.288
, pp. 181-188
-
-
Grant, R.M.1
Hecht, F.M.2
Warmerdam, M.3
-
8
-
-
0038279977
-
New classes of HIV drugs on the horizon
-
O'Brien WA. New classes of HIV drugs on the horizon. AIDS Reader 2003;13(3):S4-8.
-
(2003)
AIDS Reader
, vol.13
, Issue.3
-
-
O'Brien, W.A.1
-
9
-
-
0037323819
-
Stopping HIV fusion with enfuvirtide: The first step to extracellular HAART
-
Moyle G. Stopping HIV fusion with enfuvirtide: the first step to extracellular HAART. J Antimicrob Chemother 2003;51:213-17.
-
(2003)
J Antimicrob Chemother
, vol.51
, pp. 213-217
-
-
Moyle, G.1
-
11
-
-
0027959493
-
Peptides corresponding to a predictive alpha-helical domain of human immunodeficiency virus type 1 gp41 are potent inhibitors of virus infection
-
Wild C, Shugars D, Greenwell T, et al. Peptides corresponding to a predictive alpha-helical domain of human immunodeficiency virus type 1 gp41 are potent inhibitors of virus infection. Proc Natl Acad Sci USA 1993;91:9770-4.
-
(1993)
Proc Natl Acad Sci USA
, vol.91
, pp. 9770-9774
-
-
Wild, C.1
Shugars, D.2
Greenwell, T.3
-
12
-
-
0027692502
-
A synthetic peptide from HIV-1 gp41 is a potent inhibitor of virus-mediated cell-cell fusion
-
Wild C, Greenwell T, Matthews T. A synthetic peptide from HIV-1 gp41 is a potent inhibitor of virus-mediated cell-cell fusion. AIDS Res Hum Retroviruses 1993;9:1051-3.
-
(1993)
AIDS Res Hum Retroviruses
, vol.9
, pp. 1051-1053
-
-
Wild, C.1
Greenwell, T.2
Matthews, T.3
-
13
-
-
1142280152
-
Pentafuside, a novel inhibitor of HIV-1 and infections, is synergistic when used in combination with reverse transcriptase and protease inhibitors in vitro
-
San Diego, April 5-10
-
Barney S, Guthrie K, Davis D, et al. Pentafuside, a novel inhibitor of HIV-1 and infections, is synergistic when used in combination with reverse transcriptase and protease inhibitors in vitro. Presented at the 11th international conference on antiviral research, San Diego, April 5-10, 1998.
-
(1998)
11th International Conference on Antiviral Research
-
-
Barney, S.1
Guthrie, K.2
Davis, D.3
-
14
-
-
0007551002
-
Strong in vitro synergy between the fusion inhibitor T-20 and CXCR4 blocker AMD-3100
-
San Francisco, January 30-February 4
-
Tremblay C, Kollman C, Giguel F, et al. Strong in vitro synergy between the fusion inhibitor T-20 and CXCR4 blocker AMD-3100. Presented at the 7th conference on retroviruses and opportunistic infections, San Francisco, January 30-February 4, 2000.
-
(2000)
7th Conference on Retroviruses and Opportunistic Infections
-
-
Tremblay, C.1
Kollman, C.2
Giguel, F.3
-
15
-
-
0031729823
-
Potent suppression of HIV-1 replication in humans by T-20, a peptide inhibitor of gp41-mediated virus entry
-
Kilby JM, Hopkins S, Venetta T, et al. Potent suppression of HIV-1 replication in humans by T-20, a peptide inhibitor of gp41-mediated virus entry. Nature Med 1998;4:1302-7.
-
(1998)
Nature Med
, vol.4
, pp. 1302-1307
-
-
Kilby, J.M.1
Hopkins, S.2
Venetta, T.3
-
16
-
-
0036066762
-
The safety, plasma pharmacokinetics, and antiviral activity of subcutaneous enfuvirtide, a peptide inhibitor of gp41-mediated virus fusion, in HIV-infected adults
-
Kilby JM, Lalezari J, Eron J, et al. The safety, plasma pharmacokinetics, and antiviral activity of subcutaneous enfuvirtide, a peptide inhibitor of gp41-mediated virus fusion, in HIV-infected adults. AIDS Res Hum Retroviruses 2002;18:685-93.
-
(2002)
AIDS Res Hum Retroviruses
, vol.18
, pp. 685-693
-
-
Kilby, J.M.1
Lalezari, J.2
Eron, J.3
-
17
-
-
0037471311
-
A phase II clinical study of the long-term safety and antiviral activity of enfuvirtide-based antiretroviral therapy-T20-205
-
Lalezari J, Eron J, Carlson M, et al. A phase II clinical study of the long-term safety and antiviral activity of enfuvirtide-based antiretroviral therapy-T20-205. AIDS 2003;17:691-8.
-
(2003)
AIDS
, vol.17
, pp. 691-698
-
-
Lalezari, J.1
Eron, J.2
Carlson, M.3
-
18
-
-
0141786378
-
A week 48 assessment of a randomized, controlled, open-label phase II trial (T20-206) evaluating 3 doses of T-20 in PI-experienced, NNRTI-naive patients infected with HIV-1
-
Seattle, WA, February 24-28
-
Lalezari J, Dejesus E, Northfelt D, et al. A week 48 assessment of a randomized, controlled, open-label phase II trial (T20-206) evaluating 3 doses of T-20 in PI-experienced, NNRTI-naive patients infected with HIV-1. Presented at the 9th conference on retroviruses and opportunistic infections, Seattle, WA, February 24-28, 2002.
-
(2002)
9th Conference on Retroviruses and Opportunistic Infections
-
-
Lalezari, J.1
Dejesus, E.2
Northfelt, D.3
-
19
-
-
0003248156
-
Forty-eight week assessment of high strength T-20 in multi-class experienced patients
-
Seattle, WA, February 24-28
-
Wheat LJ, Lalezari J, Kilby M, et al. Forty-eight week assessment of high strength T-20 in multi-class experienced patients. Presented at the 9th conference on retroviruses and opportunistic infections, Seattle, WA, February 24-28, 2002.
-
(2002)
9th Conference on Retroviruses and Opportunistic Infections
-
-
Wheat, L.J.1
Lalezari, J.2
Kilby, M.3
-
20
-
-
0036335809
-
Pharmacokinetics of plasma T-20 after subcutaneous administration to patients with HIV: Inverse Gaussian density absorption and 2-compartment disposition
-
Zhang X, Nieforth K, Lang JM, et al. Pharmacokinetics of plasma T-20 after subcutaneous administration to patients with HIV: inverse Gaussian density absorption and 2-compartment disposition. Clin Pharmacol Ther 2002;72:10-19.
-
(2002)
Clin Pharmacol Ther
, vol.72
, pp. 10-19
-
-
Zhang, X.1
Nieforth, K.2
Lang, J.M.3
-
21
-
-
1142280149
-
Virological characterization of patients through 48 weeks in T20-205 who acquired enfuvirtide resistance-associated mutations during prior short-term enfuvirtide monotherapy
-
Seville, Spain, July 2-5
-
Melby T, Sista P, Nelson E, et al. Virological characterization of patients through 48 weeks in T20-205 who acquired enfuvirtide resistance-associated mutations during prior short-term enfuvirtide monotherapy [poster]. Presented at the XI international HIV drug resistance workshop: basic principles and clinical implications, Seville, Spain, July 2-5, 2002.
-
(2002)
XI International HIV Drug Resistance Workshop: Basic Principles and Clinical Implications
-
-
Melby, T.1
Sista, P.2
Nelson, E.3
-
22
-
-
0141954435
-
Enfuvirtide is optimally absorbed from three different subcutaneous injection sites
-
Barcelona, Spain, July 7-12
-
Patel IH, Lalezari J, Dorr A, et al. Enfuvirtide is optimally absorbed from three different subcutaneous injection sites [poster]. Presented at the XIV international AIDS conference, Barcelona, Spain, July 7-12, 2002.
-
(2002)
XIV International AIDS Conference
-
-
Patel, I.H.1
Lalezari, J.2
Dorr, A.3
-
24
-
-
20444432152
-
Pharmacokinetics of enfuvirtide in pediatric HIV infected patients receiving combination therapy
-
Paris, France, July 13-16
-
Bellibas SE, Siddique Z, Dorr A, et al. Pharmacokinetics of enfuvirtide in pediatric HIV infected patients receiving combination therapy. Presented at the 2nd international AIDs society conference, Paris, France, July 13-16, 2003.
-
(2003)
2nd International AIDs Society Conference
-
-
Bellibas, S.E.1
Siddique, Z.2
Dorr, A.3
-
25
-
-
0141451457
-
Enfuvirtide-investigations on the drug interactions potential in HIV-infected patients
-
Boston, February 10-14
-
Boyd M, Ruxrungtham K, Zhang X, et al. Enfuvirtide-investigations on the drug interactions potential in HIV-infected patients [poster]. Presented at the 10th conference on retroviruses and opportunistic infections, Boston, February 10-14, 2003.
-
(2003)
10th Conference on Retroviruses and Opportunistic Infections
-
-
Boyd, M.1
Ruxrungtham, K.2
Zhang, X.3
-
26
-
-
1142280148
-
6th international congress on drug therapy in HIV infection, November 17-21, 2002, Glasgow, United Kingdom [conference report]
-
McKerrow G. 6th international congress on drug therapy in HIV infection, November 17-21, 2002, Glasgow, United Kingdom [conference report]. HIV Treat Bull 2003;4(1):15. Available from http://www.i-Base.org.uk. Accessed September 15, 2003.
-
(2003)
HIV Treat Bull
, vol.4
, Issue.1
, pp. 15
-
-
McKerrow, G.1
-
27
-
-
0038576281
-
Enfuvirtide, an HIV-1 fusion inhibitor, for drug-resistant HIV infection in North and South America
-
The TORO 1 study group
-
Lalezari J, Henry K, O'Hearn M, et al. The TORO 1 study group. Enfuvirtide, an HIV-1 fusion inhibitor, for drug-resistant HIV infection in North and South America. N Engl J Med 2003;348:2175-85.
-
(2003)
N Engl J Med
, vol.348
, pp. 2175-2185
-
-
Lalezari, J.1
Henry, K.2
O'Hearn, M.3
-
28
-
-
0037849954
-
Efficacy of enfuvirtide in patients infected with drug-resistant HIV-1 in Europe and Australia (TORO 2)
-
Lazzarin A, Boneventura C, Cooper D, et al. Efficacy of enfuvirtide in patients infected with drug-resistant HIV-1 in Europe and Australia (TORO 2). N Engl J Med 2003;348:2186-95.
-
(2003)
N Engl J Med
, vol.348
, pp. 2186-2195
-
-
Lazzarin, A.1
Boneventura, C.2
Cooper, D.3
-
29
-
-
0037877259
-
Summary of pooled efficacy and safety data analyses of enfuvirtide treatment for 24 weeks in TORO 1 and TORO 2 phase III trials in highly antiretroviral treatment-experienced patients
-
Boston, February 10-14
-
Delfraissy JF, Montaner J, Eron J, et al. Summary of pooled efficacy and safety data analyses of enfuvirtide treatment for 24 weeks in TORO 1 and TORO 2 phase III trials in highly antiretroviral treatment-experienced patients [poster]. Presented at the 10th conference on retroviruses and opportunistic infections, Boston, February 10-14, 2003.
-
(2003)
10th Conference on Retroviruses and Opportunistic Infections
-
-
Delfraissy, J.F.1
Montaner, J.2
Eron, J.3
-
30
-
-
0242705329
-
Enfuvirtide TORO studies: 48 week results confirm 24 week findings
-
Paris, France, July 13-16
-
Katlama C, Arasteh K, Clotet B, et al. Enfuvirtide TORO studies: 48 week results confirm 24 week findings. Presented at the 2nd international AIDS society conference, Paris, France, July 13-16, 2003.
-
(2003)
2nd International AIDS Society Conference
-
-
Katlama, C.1
Arasteh, K.2
Clotet, B.3
-
31
-
-
1642357851
-
Analysis of virological response of enfuvirtide in TORO: Implications for patient management
-
Paris, France, July 13-16
-
Montaner J, DeMasi R, Delehanty J, et al. Analysis of virological response of enfuvirtide in TORO: implications for patient management. Presented at the 2nd international AIDS society conference, Paris, France, July 13-16, 2003.
-
(2003)
2nd International AIDS Society Conference
-
-
Montaner, J.1
DeMasi, R.2
Delehanty, J.3
-
32
-
-
0028841633
-
Predicting diabetic control from competence, adherence, adjustment, and psychopathology
-
Daviss WB, Coon H, Whitehead P, et al. Predicting diabetic control from competence, adherence, adjustment, and psychopathology. J Am Acad Child Adolesc Psychiatry 1995;34:1929-36.
-
(1995)
J Am Acad Child Adolesc Psychiatry
, vol.34
, pp. 1929-1936
-
-
Daviss, W.B.1
Coon, H.2
Whitehead, P.3
-
33
-
-
0012774034
-
Lack of influence of gp41 antibodies that cross-react with enfuvirtide on the efficacy and safety of enfuvirtide in TORO 1 and TORO 2 phase III trials
-
Boston, February 10-14
-
Walmsley S, Henry K, Katlama C, et al. Lack of influence of gp41 antibodies that cross-react with enfuvirtide on the efficacy and safety of enfuvirtide in TORO 1 and TORO 2 phase III trials [poster]. Presented at the 10th conference on retroviruses and opportunistic infections, Boston, February 10-14, 2003.
-
(2003)
10th Conference on Retroviruses and Opportunistic Infections
-
-
Walmsley, S.1
Henry, K.2
Katlama, C.3
-
34
-
-
0009834687
-
Pharmacokinetics of selected doses of T-20, a fusion inhibitor, in HIV-1 infected children
-
Chicago, February 4-8
-
Kosel B, Church J, Cunningham C, et al. Pharmacokinetics of selected doses of T-20, a fusion inhibitor, in HIV-1 infected children. Presented at the 8th conference on retroviruses and opportunistic infections, Chicago, February 4-8, 2001.
-
(2001)
8th Conference on Retroviruses and Opportunistic Infections
-
-
Kosel, B.1
Church, J.2
Cunningham, C.3
-
35
-
-
0011059972
-
Pharmacokinetics and safety of 2 mg/kg enfuvirtide in combination therapy in HIV infected children and adolescents
-
Barcelona, Spain, July 7-12
-
Bellibas SE, Pepper T, Dorr A, et al. Pharmacokinetics and safety of 2 mg/kg enfuvirtide in combination therapy in HIV infected children and adolescents [poster]. Presented at the XIV international AIDS conference, Barcelona, Spain, July 7-12, 2002.
-
(2002)
XIV International AIDS Conference
-
-
Bellibas, S.E.1
Pepper, T.2
Dorr, A.3
-
36
-
-
0031883832
-
Determinants of HIV type 1 resistance to gp41-derived inhibitory peptides
-
Rimsky L, Shugars D, Matthews T. Determinants of HIV type 1 resistance to gp41-derived inhibitory peptides. J Virol 1998;72:986-93.
-
(1998)
J Virol
, vol.72
, pp. 986-993
-
-
Rimsky, L.1
Shugars, D.2
Matthews, T.3
-
37
-
-
0012885271
-
Characterization of baseline and treatment-emergent resistance to enfuvirtide observed in phase II clinic trials: Substitutions in gp41 amino acids (36-45) and enfuvirtide susceptibility of virus isolates
-
Sista P, Melby T, Greenberg M, et al. Characterization of baseline and treatment-emergent resistance to enfuvirtide observed in phase II clinic trials: substitutions in gp41 amino acids (36-45) and enfuvirtide susceptibility of virus isolates [abstr]. Antiviral Ther 2002;7:S16.
-
(2002)
Antiviral Ther
, vol.7
-
-
Sista, P.1
Melby, T.2
Greenberg, M.3
-
38
-
-
0038069784
-
Impact of HIV-1 gp41 amino acid substitutions (positions 36-45) on susceptibility of T-20 in vitro: Analysis of primary virus isolates recovered from patients during chronic enfuvirtide treatment and site-directed mutants in NL4-3
-
Mink M, Greenberg M, Mosier S, et al. Impact of HIV-1 gp41 amino acid substitutions (positions 36-45) on susceptibility of T-20 in vitro: analysis of primary virus isolates recovered from patients during chronic enfuvirtide treatment and site-directed mutants in NL4-3 [abstr]. Antiviral Ther 2002;7:S17.
-
(2002)
Antiviral Ther
, vol.7
-
-
Mink, M.1
Greenberg, M.2
Mosier, S.3
-
39
-
-
0037539498
-
Fitness of HIV-1 clinical isolates resistant to enfuvirtide
-
Lu J, Cammack N, Kuritzkes D. Fitness of HIV-1 clinical isolates resistant to enfuvirtide [abstr]. Antiviral Ther 2002;7:S56.
-
(2002)
Antiviral Ther
, vol.7
-
-
Lu, J.1
Cammack, N.2
Kuritzkes, D.3
-
40
-
-
1142280147
-
In vitro antiviral activity of T-20 against HIV-1 carrying resistance mutations to reverse transcriptase and protease inhibitors
-
Nutley, NJ: Roche Pharmaceuticals, January
-
Sista P. In vitro antiviral activity of T-20 against HIV-1 carrying resistance mutations to reverse transcriptase and protease inhibitors. Investigator brochure, version 5, research report 1007507. Nutley, NJ: Roche Pharmaceuticals, January 2002.
-
(2002)
Investigator Brochure, Version 5, Research Report 1007507
-
-
Sista, P.1
-
41
-
-
0012823617
-
Baseline and on-treatment susceptibility to enfuvirtide seen in TORO 1 and TORO 2 to 24 weeks
-
Boston, February 10-14
-
Greenberg M, Melby T, Sista P, et al. Baseline and on-treatment susceptibility to enfuvirtide seen in TORO 1 and TORO 2 to 24 weeks. Presented at the 10th conference on retroviruses and opportunistic infections, Boston, February 10-14, 2003.
-
(2003)
10th Conference on Retroviruses and Opportunistic Infections
-
-
Greenberg, M.1
Melby, T.2
Sista, P.3
-
42
-
-
0012765066
-
Pathology of injection site reactions with enfuvirtide (T-20)
-
Boston, February 10-14
-
Ball R, Kinchelow T, for the ISR Substudy Group. Pathology of injection site reactions with enfuvirtide (T-20) [poster]. Presented at the 10th conference on retroviruses and opportunistic infections, Boston, February 10-14, 2003.
-
(2003)
10th Conference on Retroviruses and Opportunistic Infections
-
-
Ball, R.1
Kinchelow, T.2
-
43
-
-
0036315615
-
Long-term treatment with subcutaneous T-20, a fusion inhibitor, in HIV-infected patients: Patient satisfaction and impact on activity of daily living
-
Cohen C, Dusek A, Green J, et al. Long-term treatment with subcutaneous T-20, a fusion inhibitor, in HIV-infected patients: patient satisfaction and impact on activity of daily living. AIDS Patient Care STDs 2002;16(7):327-35.
-
(2002)
AIDS Patient Care STDs
, vol.16
, Issue.7
, pp. 327-335
-
-
Cohen, C.1
Dusek, A.2
Green, J.3
-
44
-
-
0141989147
-
Patient survey on injection of enfuvirtide: Ease of use and impact on activities
-
Barcelona, Spain, July 7-12
-
Green J, Salgo MP, Delehanty J. Patient survey on injection of enfuvirtide: ease of use and impact on activities [poster]. Presented at the XIV international AIDS conference, Barcelona, Spain, July 7-12, 2002.
-
(2002)
XIV International AIDS Conference
-
-
Green, J.1
Salgo, M.P.2
Delehanty, J.3
-
45
-
-
1142292233
-
Impact of enfuvirtide on health-related quality of life
-
Paris, France, July 13-16
-
Cohen C, Clumeck N, Molina JM, et al. Impact of enfuvirtide on health-related quality of life. Presented at the 2nd international AIDS society conference, Paris, France, July 13-16, 2003.
-
(2003)
2nd International AIDS Society Conference
-
-
Cohen, C.1
Clumeck, N.2
Molina, J.M.3
|