Hypertrophic Cardiomyopathy - Sports-Related Aspects of Diagnosis, Therapy, and Sports Eligibility

International Journal of Sports Medicine

Volumn 25, Issue 1, 2004, Pages 20-26

  Hipp, A A ^a,c   Heitkamp, H C ^a   Rocker K ^b   Dickhuth, H H ^b  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b UNIVERSITY OF FREIBURG   (Germany)

^c UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

Author keywords

Hypertrophic cardiomyopathy; Prevention; Sports eligibility; Sudden cardiac death

Indexed keywords

PROPRANOLOL;

ADULT; AGED; ATHLETE; BICYCLE; BLOOD PRESSURE; CASE REPORT; DIZZINESS; DYNAMICS; ELECTROCARDIOGRAPHY; EXERCISE; EXERCISE TEST; FAMILY HISTORY; HEART ARRHYTHMIA; HEART RATE; HEART SEPTUM DEFECT; HEART VENTRICLE PRESSURE; HUMAN; HYPERTROPHIC CARDIOMYOPATHY; HYPERTROPHY; NAUSEA; PATIENT MONITORING; PATIENT POSITIONING; PHYSICAL EXAMINATION; REVIEW; RISK ASSESSMENT; RISK FACTOR; RUNNING; SPORT; SWEATING; SYSTOLIC HEART MURMUR; TASK PERFORMANCE; TREADMILL EXERCISE;

CARDIOMYOPATHY, HYPERTROPHIC; DEATH, SUDDEN, CARDIAC; DIAGNOSTIC IMAGING; EXERCISE TEST; HUMANS; PRACTICE GUIDELINES; SPORTS MEDICINE;

EID: 1142291685     PISSN: 01724622     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2003-45227     Document Type: Review

References (45)

1. Burke AP, Farb A, Virmani R, Goodin J, Smialek JE. Sports related and non-sports related sudden cardiac death in young adults. Am Heart J 1991; 121: 568-575
2. Cecchi F, Maron B, Epstein S. Long-term outcome of patients with hypertrophic cardiomyopathy successfully resuscitated after cardiac arrest. J Am Coll Cardiol 1989; 13: 1283-1288
3. Corrado D, Basso C, Schiavon M, Thiene G. Screening for hypertrophic cardiomyopathy in young athletes. N Engl J Med 1998; 339: 364-369
4. Dickhuth HH, Röcker K, Hipp A, Heitkamp HC, Keul J. Echocardiographic findings in endurance athletes with hypertrophic non-obstructive cardiomyopathy (HNCM) compared to non-athletes with HNCM and to physiological hypertrophy (athlete's heart). Int J Sports Med 1994; 15: 273-277
5. Elliott PM, Poloniecki J, Dickie S, Sharma S, Monserrat L, Varnava A, Mahon NG, McKenna WJ. Sudden death in hypertrophic cardiomyopathy: identification of high risk patients. J Am Coll Cardiol 2000; 36: 2212-2218
6. Faber L, Meissner A, Ziemssen P, Seggewiss H. Percutaneous transluminal septal myocardial ablation for hypertrophic obstructive cardiomyopathy: long-term follow up of the first series of 25 patients. Heart 2000; 83: 326-331
7. Geisterfer-Lowrance AA, Christe M, Conner DA, Ingwall JS, Schoen FJ, Seidman CE, Seidman JG. A mouse model of familial hypertrophic cardiomyopathy. Science 1996; 272: 731-734
8. Hagège AA, Dubourg O, Desnos M, Mirochnik R, Isnard G, Bonne G, Carrier L, Guicheney P, Bouhour JB, Schwartz K, Komajda M. Familial hypertrophic cardiomyopathy - cardiac ultrasonic abnormalities in genetically affected subjects without echocardiographic evidence of left ventricular hypertrophy. Eur Heart J 1998; 19: 490-499
9. International Federation of Sports Medicine (FIMS). Scientific Committee Recommendations for medical evaluation and sports participation in athletes with a family history of sudden cardiac death. In: International Sports Medicine Directory. Human Kinetics, 2001: 247-248
10. Lim DS, Lutucuta S, Bachireddy P, Youker K, Evans A, Entman M, Roberts R, Marian AJ. Angiotensin II blockade reverses myocardial fibrosis in a transgenic mouse model of human hypertrophic cardiomyopathy. Circulation 2001; 103: 789-791
11. Malik M. Heart rate variability. Standards of measurement, physiological interpretation and clinical use. Circulation 1996; 93: 1043-1065
12. Marian A, Roberts R. The molecular genetic basis for hypertrophic cardiomyopathy. J Mol Cell Cardiol 2001; 33: 655-670
13. Maron BJ. Hypertrophic cardiomyopathy - a systematic review. J Am Med Ass 2002; 287: 1308-1320
14. Maron BJ, Bonow RO, Cannon RO, Leon MB, Epstein SE. Hypertrophic cardiomyopathy: interrelation of clinical manifestations, pathophysiology, and therapy. N Engl J Med 1987; 316: 844-852
15. Maron BJ, Casey SA, Poliac LC, Gohman TE, Almquist AK, Aeppli DM. Clinical course of hypertrophic cardiomyopathy in a regional United States cohort. J Am Med Ass 1999; 281: 650-655
16. Maron BJ, Cecchi F, McKenna WJ. Risk factors and current status of risk stratification profiles for sudden cardiac death in patients with hypertrophic cardiomyopathy. Br Heart J 1994; 72 (suppl): 14-18
17. Maron BJ, Epstein SE, Roberts WC. Hypertrophic cardiomyopathy and transmural myocardial infarction without significant atherosclerosis of the extramural coronary arteries. Am J Cardiol 1979; 43: 1086-1102
18. Maron BJ, Fananapazir L. Sudden cardiac death in hypertrophic cardiomyopathy. Circulation 1992; 85 (suppl 1): 57-63
19. Maron BJ, Isner JM, McKenna WJ. Task Force 3: Hypertrophic cardiomyopathy, myocarditis and other myocardial diseases and mitral valve prolapse. J Am Coll Cardiol 1994; 24: 880-882
20. Maron BJ, Klues HG. Surviving competitive athletics with hypertrophic cardiomyopathy. Am J Cardiol 1994; 73: 1098-1104
21. Maron BJ, Moller JH, Seidman CE, Vincent GM, Dietz HC, Moss AJ, Towbin JA, Sondheimer HM, Pyeritz RE, McGee G, Epstein AE. Impact of laboratory molecular diagnosis on contemporary diagnostic criteria for genetically transmitted cardiovascular diseases: hypertrophic cardiomyopathy, long QT-syndrome, and Marfan syndrome: a statement for healthcare professionals from the councils on clinical cardiology, cardiovascular disease in the young, and basic science, American Heart Association. Circulation 1998; 98: 1460-1471
22. Maron BJ, Nishimura RA, McKenna WJ, Rakowski H, Josephson ME, Kieval RS. Assessment of permanent dual chamber pacing as a treatment for drug refractory symptomatic patients with obstructive hypertrophic cardiomyopathy. A randomized, double-blind, crossover study (M-Pathy). Circulation 1999; 99: 2927-2933
23. Maron BJ, Roberts WC, Epstein SE. Sudden death in hypertrophic cardiomyopathy: a profile of 78 patients. Circulation 1982; 67: 1388-1394
24. Maron BJ, Shen WK, Link MS, Epstein AE, Almquist AK, Daubert JP, Bardy GH, Favale S, Rea RF, Boriani G, Ill ME, Spirito P. Efficacy of implantable cardioverter-defibrillators for the prevention of sudden death in patients with hypertrophic cardiomyopathy. N Engl J Med 2000; 342: 365-373
25. Maron MS, Olivotto I, Betocchi S, Casey SA, Lesser JR, Losi MA, Cecchi F, Maron BJ. Effect of left ventricular outflow tract obstruction on clinical outcome in hypertrophic cardiomyopathy. N Engl J Med 2003; 348: 295-303
26. McKenna WJ, Camm AJ. Sudden death in hypertrophic cardiomyopathy. Assessment of patients at high risk. Circulation 1989; 80: 1489-1492
27. McKenna WJ, Coccolo F, Elliott PM. Genes and disease expression in hypertrophic cardiomyopathy. Lancet 1998; 352: 1162-1163
28. McKenna WJ, Oakley CM, Krikler DM, Goodwin JF. Improved survival with amiodarone in patients with hypertrophic cardiomyopathy and ventricular tachycardia. Br Heart J 1985; 53: 412-416
29. Mitchell JH, Haskel WL, Raven PB. Classification of sports. J Am Coll Cardiol 1994; 24: 864-866
30. Mohiddin SA, Begley D, Shih J, Fananapazir L. Myocardial bridging does not predict sudden death in children with hypertrophic cardiomyopathy but is associated with more severe cardiac disease. J Am Coll Cardiol 2000; 36: 2270-2278
31. Momiyama Y, Hartikainen J, Nagayoshi H, Albrecht P, Kautzner J, Saumarez RC, McKenna WJ, Camm AJ. Exercise-induced T-wave alternans as a marker of high risk in patients with hypertrophic cardiomyopathy. Japn Circ J 1997; 61: 650-656
32. Murda'h M, McKenna WJ, Camm AJ. Repolarization alternans: Techniques, mechanisms, and cardiac vulnerability. Pace 1997; 20: 2641-2657
33. Nagueh S, Bachinski L, Meyer D, Hill R, Zoghbi WA, Tam JW, Quinones MA, Roberts R, Marian AJ. Tissue Doppler imaging consistently detects myocardial abnormalities in patients with hypertrophic cardiomyopathy and provides a novel means for an early diagnosis before and independently of hypertrophy. Circulation 2001; 104: 128-130
34. Olivotto I, Montereggi A, Mazzuoli F, Cecchi F. Clinical utility and safety of exercise testing in patients with hypertrophic cardiomyopathy. G Ital Cardiol 1999; 29: 11-19
35. Ostman-Smith I, Wettrell G, Riesenfeld T. A cohort study of childhood hypertrophic cardiomyopathy: improved survival following high-dose β-adrenoceptor antagonist treatment. J Am Coll Cardiol 1999; 34: 1813-1822
36. Pinsky DJ, Sciacca RR, Steinberg JS. QT-Dispersion as a marker of risk in patients awaiting heart transplantation. J Am Coll Cardiol 1997; 29: 1576-1584
37. Raschka C, Parzeller M, Kind M, Banzer W. Organpathologische Ursachen des akuten Sporttodes in Deutschland, Österreich und der deutschsprachigen Schweiz. Deutsch Z Sportmed 1998; 49: 157-160
38. Roberts R, Sigwart U. New concepts in hypertrophic cardiomyopathies, part I. Circulation 2001; 104: 2113-2116
39. Roberts R, Sigwart U. New concepts in hypertrophic cardiomyopathies, part II. Circulation 2001; 104: 2249-2252
40. Spirito P, Maron BJ. Perspectives on the role of new treatment strategies in hypertrophic obstructive cardiomyopathy. J Am Coll Cardiol 1999; 33: 1071-1075
41. Spirito P, Seidman CE, McKenna WJ, Maron BJ. The management of hypertrophic cardiomyopathy. N Engl J Med 1997; 336: 775-785
42. Tabib A, Miras A, Taniere P, Loire R. Undetected cardiac lesions cause unexpected sudden cardiac death during occasional sport activity - a report on 80 cases. Eur Heart J 1999; 20: 900-903
43. Varnava A, Baboonian C, Davison F, de Cruz L, Elliott PM, Davies MJ, McKenna WJ. A new mutation of the cardiac troponin T gene causing familial hypertrophic cardiomyopathy without left ventricular hypertrophy. Heart 1999; 82: 621-624
44. Watkins H. Sudden death in hypertrophic cardiomyopathy. N Engl J Med 2000; 342: 422-423
45. Yetman AT, McCrindle BW, MacDonald C, Freedom RM, Gow R. Myocardial bridging in children with hypertrophic cardiomyopathy - a risk factor for sudden death. N Engl J Med 1998; 339: 1201-1209