-
2
-
-
0038036765
-
High-dose chemotherapy with hematopoietic stem-cell rescue for high-risk breast cancer
-
Rodenhuis S, Bontenbal M, Beex LV, et al. High-dose chemotherapy with hematopoietic stem-cell rescue for high-risk breast cancer. N Engl J Med 2003;349:7-16.
-
(2003)
N Engl J Med
, vol.349
, pp. 7-16
-
-
Rodenhuis, S.1
Bontenbal, M.2
Beex, L.V.3
-
3
-
-
7344254625
-
Randomised trial of high-dose chemotherapy and haemopoietic progenitor-cell support in operable breast cancer with extensive axillary lymph-node involvement
-
Rodenhuis S, Richel DJ, Van Der Wall E, et al. Randomised trial of high-dose chemotherapy and haemopoietic progenitor-cell support in operable breast cancer with extensive axillary lymph-node involvement. Lancet 1998;352:515-21.
-
(1998)
Lancet
, vol.352
, pp. 515-521
-
-
Rodenhuis, S.1
Richel, D.J.2
Van Der Wall, E.3
-
4
-
-
0029978783
-
Feasibility of multiple courses of high-dose cyclophosphamide, thiotepa, and carboplatin for breast cancer or germ cell cancer
-
Rodenhuis S, Westerman A, Holtkamp MJ, et al. Feasibility of multiple courses of high-dose cyclophosphamide, thiotepa, and carboplatin for breast cancer or germ cell cancer. J Clin Oncol 1996;14:1473-83.
-
(1996)
J Clin Oncol
, vol.14
, pp. 1473-1483
-
-
Rodenhuis, S.1
Westerman, A.2
Holtkamp, M.J.3
-
5
-
-
0033374916
-
A multi-center prospective phase II study of high-dose chemotherapy in germ-cell cancer patients relapsing from complete remission
-
Rodenhuis S, De Wit R, De Mulder PHM, et al. A multi-center prospective phase II study of high-dose chemotherapy in germ-cell cancer patients relapsing from complete remission. Ann Oncol 1999;10:1467-73.
-
(1999)
Ann Oncol
, vol.10
, pp. 1467-1473
-
-
Rodenhuis, S.1
De Wit, R.2
De Mulder, P.H.M.3
-
6
-
-
0034898542
-
Phase II study of a multi-course high-dose chemotherapy regimen incorporating cyclophosphamide, thiotepa, and carboplatin in stage IV breast cancer
-
Schrama JG, Baars JW, Holtkamp MJ, Schornagel JH, Beijnen JH, Rodenhuis S. Phase II study of a multi-course high-dose chemotherapy regimen incorporating cyclophosphamide, thiotepa, and carboplatin in stage IV breast cancer. Bone Marrow Transplant 2001;28:173-80.
-
(2001)
Bone Marrow Transplant
, vol.28
, pp. 173-180
-
-
Schrama, J.G.1
Baars, J.W.2
Holtkamp, M.J.3
Schornagel, J.H.4
Beijnen, J.H.5
Rodenhuis, S.6
-
8
-
-
0034254283
-
Chemistry, pharmacology and pharmacokinetics of N,N′,N- triethylenethiophosphoramide (ThioTEPA)
-
Van Maanen MJ, Smeets CJ, Beijnen JH. Chemistry, pharmacology and pharmacokinetics of N,N′,N-triethylenethiophosphoramide (ThioTEPA). Cancer Treat Rev 2000;26:257-68.
-
(2000)
Cancer Treat Rev
, vol.26
, pp. 257-268
-
-
Van Maanen, M.J.1
Smeets, C.J.2
Beijnen, J.H.3
-
9
-
-
0036090053
-
Cytochrome P450 isozymes 3A4 and 2B6 are involved in the in vitro human metabolism of thiotepa to tepa
-
Jacobson PA, Green K, Birnbaum A, Remmel RP. Cytochrome P450 isozymes 3A4 and 2B6 are involved in the in vitro human metabolism of thiotepa to tepa. Cancer Chemother Pharmacol 2002;49:461-7.
-
(2002)
Cancer Chemother Pharmacol
, vol.49
, pp. 461-467
-
-
Jacobson, P.A.1
Green, K.2
Birnbaum, A.3
Remmel, R.P.4
-
10
-
-
0029011523
-
Modulation of thioTEPA anti-tumor activity in-vivo by alteration of liver cytochrome P450-catalyzed drug-metabolism
-
Chang TKH, Chen G, Waxman DJ. Modulation of thioTEPA anti-tumor activity in-vivo by alteration of liver cytochrome P450-catalyzed drug-metabolism. J Pharmacol Exp Ther 1995;274:270-5.
-
(1995)
J Pharmacol Exp Ther
, vol.274
, pp. 270-275
-
-
Chang, T.K.H.1
Chen, G.2
Waxman, D.J.3
-
11
-
-
0024459584
-
Evidence for enzymatic activation and oxygen involvement in cytotoxicity and anti-tumor activity of N,N′,N-triethylenethiophosphoramide
-
Teicher BA, Waxman DJ, Holden SA, et al. Evidence for enzymatic activation and oxygen involvement in cytotoxicity and anti-tumor activity of N,N′,N-triethylenethiophosphoramide. Cancer Res 1989;49:4996-5001.
-
(1989)
Cancer Res
, vol.49
, pp. 4996-5001
-
-
Teicher, B.A.1
Waxman, D.J.2
Holden, S.A.3
-
12
-
-
0023788545
-
Cellular pharmacology of N,N′,N-triethylenethiophosphoramide
-
Miller B, Tenenholz T, Egorin MJ, Sosnovsky G, Rao NU, Gutierrez PL. Cellular pharmacology of N,N′,N-triethylenethiophosphoramide. Cancer Lett 1988;41:157-68.
-
(1988)
Cancer Lett
, vol.41
, pp. 157-168
-
-
Miller, B.1
Tenenholz, T.2
Egorin, M.J.3
Sosnovsky, G.4
Rao, N.U.5
Gutierrez, P.L.6
-
13
-
-
3142718815
-
Integrated population pharmacokinetic model of both cyclophosphamide and thiotepa suggesting a mutual drug-drug interaction
-
De Jonge ME, Huitema ADR, Rodenhuis S, Beijnen JH. Integrated population pharmacokinetic model of both cyclophosphamide and thiotepa suggesting a mutual drug-drug interaction. J Pharmacokinet Pharmacodyn 2004;31:135-56.
-
(2004)
J Pharmacokinet Pharmacodyn
, vol.31
, pp. 135-156
-
-
De Jonge, M.E.1
Huitema, A.D.R.2
Rodenhuis, S.3
Beijnen, J.H.4
-
14
-
-
0026045802
-
Clinical Pharmacokinetics of carboplatin
-
Van Der Vijgh WJM. Clinical Pharmacokinetics of carboplatin. Clin Pharmacokinet 1991;21:242-61.
-
(1991)
Clin Pharmacokinet
, vol.21
, pp. 242-261
-
-
Van Der Vijgh, W.J.M.1
-
15
-
-
0036018898
-
Relationship between exposure and toxicity in high-dose chemotherapy with cyclophosphamide, thioTEPA and carboplatin
-
Huitema ADR, Spaander M, Mathôt RAA, et al. Relationship between exposure and toxicity in high-dose chemotherapy with cyclophosphamide, thioTEPA and carboplatin. Ann Oncol 2002;13:374-84.
-
(2002)
Ann Oncol
, vol.13
, pp. 374-384
-
-
Huitema, A.D.R.1
Spaander, M.2
Mathôt, R.A.A.3
-
16
-
-
0038575269
-
Toxicity of the high-dose chemotherapy CTC regimen (cyclophosphamide, thiotepa, carboplatin): The Netherlands Cancer Institute experience
-
Schrama JG, Holtkamp MJ, Baars JW, Schornagel JH, Rodenhuis S. Toxicity of the high-dose chemotherapy CTC regimen (cyclophosphamide, thiotepa, carboplatin): the Netherlands Cancer Institute experience. Br J Cancer 2003;88:1831-8.
-
(2003)
Br J Cancer
, vol.88
, pp. 1831-1838
-
-
Schrama, J.G.1
Holtkamp, M.J.2
Baars, J.W.3
Schornagel, J.H.4
Rodenhuis, S.5
-
17
-
-
0026748897
-
Cyclophosphamide pharmacokinetics: Correlation with cardiac toxicity and tumor response
-
Ayash LJ, Wright JE, Tretyakov O, et al. Cyclophosphamide pharmacokinetics: correlation with cardiac toxicity and tumor response. J Clin Oncol 1992;10:995-1000.
-
(1992)
J Clin Oncol
, vol.10
, pp. 995-1000
-
-
Ayash, L.J.1
Wright, J.E.2
Tretyakov, O.3
-
18
-
-
0036307688
-
Association of high-dose cyclophosphamide, cisplatin, and carmustine pharmacokinetics with survival, toxicity, and dosing weight in patients with primary breast cancer
-
Petros WP, Broadwater G, Berry D, et al. Association of high-dose cyclophosphamide, cisplatin, and carmustine pharmacokinetics with survival, toxicity, and dosing weight in patients with primary breast cancer. Clin Cancer Res 2002;8:698-705.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 698-705
-
-
Petros, W.P.1
Broadwater, G.2
Berry, D.3
-
19
-
-
0028839172
-
Dosing of thiotepa for myeloablative therapy
-
Przepiorka D, Madden T, Ippoliti C, Estrov Z, Dimopoulos M. Dosing of thiotepa for myeloablative therapy. Cancer Chemother Pharmacol 1995;37:155-60.
-
(1995)
Cancer Chemother Pharmacol
, vol.37
, pp. 155-160
-
-
Przepiorka, D.1
Madden, T.2
Ippoliti, C.3
Estrov, Z.4
Dimopoulos, M.5
-
20
-
-
0023732042
-
Cyclophosphamide and thiotepa with autologous bone marrow transplantation in patients with solid tumors
-
Eder JP, Antman K, Elias A, et at. Cyclophosphamide and thiotepa with autologous bone marrow transplantation in patients with solid tumors. J Natl Cancer Inst 1988;80:1221-6.
-
(1988)
J Natl Cancer Inst
, vol.80
, pp. 1221-1226
-
-
Eder, J.P.1
Antman, K.2
Elias, A.3
-
21
-
-
0029874346
-
A phase I/II study of high-dose cyclophosphamide, cisplatin, and thiotepa followed by autologous bone marrow and granulocyte colony-stimulating factor-primed peripheral blood progenitor cells in patients with advanced malignancies
-
Hussein AM, Petros WP, Ross M, et al. A phase I/II study of high-dose cyclophosphamide, cisplatin, and thiotepa followed by autologous bone marrow and granulocyte colony-stimulating factor-primed peripheral blood progenitor cells in patients with advanced malignancies. Cancer Chemother Pharmacol 1996;37:561-8.
-
(1996)
Cancer Chemother Pharmacol
, vol.37
, pp. 561-568
-
-
Hussein, A.M.1
Petros, W.P.2
Ross, M.3
-
22
-
-
0029921559
-
Pharmacokinetics and pharmacodynamics of carboplatin administered in a high-dose combination regimen with thiotepa, cyclophosphamide and peripheral stem cell support
-
Van Warmerdam LJC, Rodenhuis S, Van Der Wall E, Maes RAA, Beijnen JH. Pharmacokinetics and pharmacodynamics of carboplatin administered in a high-dose combination regimen with thiotepa, cyclophosphamide and peripheral stem cell support. Br J Cancer 1996;73:979-84.
-
(1996)
Br J Cancer
, vol.73
, pp. 979-984
-
-
Van Warmerdam, L.J.C.1
Rodenhuis, S.2
Van Der Wall, E.3
Maes, R.A.A.4
Beijnen, J.H.5
-
23
-
-
0024553731
-
A phase I clinical and pharmacokinetic study of carboplatin and autologous bone marrow support
-
Shea TC, Flaherty M, Elias A, et al. A phase I clinical and pharmacokinetic study of carboplatin and autologous bone marrow support. J Clin Oncol 1989;7:651-61.
-
(1989)
J Clin Oncol
, vol.7
, pp. 651-661
-
-
Shea, T.C.1
Flaherty, M.2
Elias, A.3
-
24
-
-
0029010195
-
High-dose ifosfamide, carboplatin, and etoposide pharmacokinetics: Correlation of plasma drug levels with renal toxicity
-
Wright JE, Elias A, Tretyakov O, et al. High-dose ifosfamide, carboplatin, and etoposide pharmacokinetics: correlation of plasma drug levels with renal toxicity. Cancer Chemother Pharmacol 1995;36:345-51.
-
(1995)
Cancer Chemother Pharmacol
, vol.36
, pp. 345-351
-
-
Wright, J.E.1
Elias, A.2
Tretyakov, O.3
-
25
-
-
0036236332
-
High-dose carboplatin and regimen-related toxicity following autologous bone marrow transplant
-
Colby C, Koziol S, McAfee SL, Yeap B, Spitzer TR. High-dose carboplatin and regimen-related toxicity following autologous bone marrow transplant. Bone Marrow Transplant 2002;26:467-72.
-
(2002)
Bone Marrow Transplant
, vol.26
, pp. 467-472
-
-
Colby, C.1
Koziol, S.2
McAfee, S.L.3
Yeap, B.4
Spitzer, T.R.5
-
26
-
-
0035998753
-
Toxicity of high-dose carboplatin: Ultrafiltered and not total plasma pharmacokinetics is of clinical relevance
-
Kloft C, Siegert W, Beyer J, Jaehde U. Toxicity of high-dose carboplatin: ultrafiltered and not total plasma pharmacokinetics is of clinical relevance. J Clin Pharmacol 2002;42:762-73.
-
(2002)
J Clin Pharmacol
, vol.42
, pp. 762-773
-
-
Kloft, C.1
Siegert, W.2
Beyer, J.3
Jaehde, U.4
-
27
-
-
0035146029
-
Population pharmacokinetics of thiotepa and its active metabolite tepa in high-dose chemotherapy
-
Huitema ADR, Mathôt RAA, Tibben MM, Schellens JHM, Rodenhuis S, Beijnen JH. Population pharmacokinetics of thiotepa and its active metabolite tepa in high-dose chemotherapy. Br J Clin Pharmacol 2001;51:61-70.
-
(2001)
Br J Clin Pharmacol
, vol.51
, pp. 61-70
-
-
Huitema, A.D.R.1
Mathôt, R.A.A.2
Tibben, M.M.3
Schellens, J.H.M.4
Rodenhuis, S.5
Beijnen, J.H.6
-
28
-
-
0034131494
-
Validation of techniques for the prediction of carboplatin exposure: Application of Bayesian methods
-
Huitema ADR, Mathôt RAA, Tibben MM, Schellens JH, Rodenhuis S, Beijnen JH. Validation of techniques for the prediction of carboplatin exposure: application of Bayesian methods. Clin Pharmacol Ther 2000;67:621-30.
-
(2000)
Clin Pharmacol Ther
, vol.67
, pp. 621-630
-
-
Huitema, A.D.R.1
Mathôt, R.A.A.2
Tibben, M.M.3
Schellens, J.H.4
Rodenhuis, S.5
Beijnen, J.H.6
-
29
-
-
0024440650
-
Carboplatin dosage: Prospective evaluation of a simple formula based on renal function
-
Calvert AH, Newell DR, Gumbrell LA, et al. Carboplatin dosage: prospective evaluation of a simple formula based on renal function. J Clin Oncol 1989;7:1748-56.
-
(1989)
J Clin Oncol
, vol.7
, pp. 1748-1756
-
-
Calvert, A.H.1
Newell, D.R.2
Gumbrell, L.A.3
-
30
-
-
0016916438
-
Prediction of creatinine clearance from serum creatinine
-
Cockcroft DW, Gault MH. Prediction of creatinine clearance from serum creatinine. Nephron 1976;16:31-41.
-
(1976)
Nephron
, vol.16
, pp. 31-41
-
-
Cockcroft, D.W.1
Gault, M.H.2
-
31
-
-
1642298855
-
Simultaneous quantification of cyclophosphamide, 4- hydroxycyclophosphamide, N,N′,N-triethylenethiophosphoramide (thiotepa) and N,N′,N-triethylenephosphoramide (tepa) in human plasma by high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry (LC-MS-MS)
-
De Jonge ME, Van Dam SM, Hillebrand MJX, et al. Simultaneous quantification of cyclophosphamide, 4-hydroxycyclophosphamide, N,N′,N-triethylenethiophosphoramide (thiotepa) and N,N′,N- triethylenephosphoramide (tepa) in human plasma by high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry (LC-MS-MS). J Mass Spectrom 2004;39:262-71.
-
(2004)
J Mass Spectrom
, vol.39
, pp. 262-271
-
-
De Jonge, M.E.1
Van Dam, S.M.2
Hillebrand, M.J.X.3
-
32
-
-
4243825646
-
Validated method for the determination of carboplatin in biological fluids by Zeeman atomic absorption spectrometry
-
Van Warmerdam LJC, Van Tellingen O, Maes RAA, Beijnen JH. Validated method for the determination of carboplatin in biological fluids by Zeeman atomic absorption spectrometry. Fresenius J Anal Chem 1995;352:777-81.
-
(1995)
Fresenius J Anal Chem
, vol.352
, pp. 777-781
-
-
Van Warmerdam, L.J.C.1
Van Tellingen, O.2
Maes, R.A.A.3
Beijnen, J.H.4
-
33
-
-
0032566628
-
Simultaneous determination of N,N'′,N-triethylenethiophosphoramide, cyclophosphamide and some of their metabolites in plasma using capillary gas chromatography
-
Huitema ADR, Tibben MM, Kerbusch T, Zwikker JW, Rodenhuis S, Beijnen JH. Simultaneous determination of N,N'′,N-triethylenethiophosphoramide, cyclophosphamide and some of their metabolites in plasma using capillary gas chromatography. J Chromatogr B Biomed Sci Appl 1998;716:177-86.
-
(1998)
J Chromatogr B Biomed Sci Appl
, vol.716
, pp. 177-186
-
-
Huitema, A.D.R.1
Tibben, M.M.2
Kerbusch, T.3
Zwikker, J.W.4
Rodenhuis, S.5
Beijnen, J.H.6
-
34
-
-
0003747347
-
-
NONMEM Project Group. San Francisco: University of California at San Francisco
-
Beal SL, Sheiner LB. NONMEM user's guides. NONMEM Project Group. San Francisco: University of California at San Francisco; 1998.
-
(1998)
NONMEM User's Guides
-
-
Beal, S.L.1
Sheiner, L.B.2
-
35
-
-
0003506745
-
-
Bethesda (MD): Division of Cancer Treatment, National Cancer Institute
-
Division of Cancer Treatment, National Cancer Institute. Guidelines for reporting of adverse drug reactions. Bethesda (MD): Division of Cancer Treatment, National Cancer Institute; 1998.
-
(1998)
Guidelines for Reporting of Adverse Drug Reactions
-
-
-
36
-
-
0028838485
-
Comparison of methods for the estimation of carboplatin pharmacokinetics in paediatric cancer patients
-
Peng B, Boddy AV, Cole M, et al. Comparison of methods for the estimation of carboplatin pharmacokinetics in paediatric cancer patients. Eur J Cancer 1995;31A:1804-10.
-
(1995)
Eur J Cancer
, vol.31 A
, pp. 1804-1810
-
-
Peng, B.1
Boddy, A.V.2
Cole, M.3
-
37
-
-
0031657664
-
Pharmacokinetics of cyclophosphamide and its metabolites in bone-marrow transplantation patients
-
Ren S, Kalhorn TF, McDonald GB, Anasetti C, Appelbaum FR, Slattery JT. Pharmacokinetics of cyclophosphamide and its metabolites in bone-marrow transplantation patients. Clin Pharmacol Ther 1998;64:289-301.
-
(1998)
Clin Pharmacol Ther
, vol.64
, pp. 289-301
-
-
Ren, S.1
Kalhorn, T.F.2
McDonald, G.B.3
Anasetti, C.4
Appelbaum, F.R.5
Slattery, J.T.6
-
38
-
-
0021167354
-
Plasma concentrations of 4-hydroxycyclophosphamide and phosphoramide mustard in patients repeatedly given high doses of cyclophosphamide in preparation for bone marrow transplantation
-
Sladek NE, Doeden D, Powers JF, Krivit W. Plasma concentrations of 4-hydroxycyclophosphamide and phosphoramide mustard in patients repeatedly given high doses of cyclophosphamide in preparation for bone marrow transplantation. Cancer Treat Rep 1984;68:1247-54.
-
(1984)
Cancer Treat Rep
, vol.68
, pp. 1247-1254
-
-
Sladek, N.E.1
Doeden, D.2
Powers, J.F.3
Krivit, W.4
-
39
-
-
0030994518
-
Dose escalation of cyclophosphamide in patients with breast cancer: Consequences for pharmacokinetics and metabolism
-
Busse D, Busch FW, Bohnenstengel F, et al. Dose escalation of cyclophosphamide in patients with breast cancer: consequences for pharmacokinetics and metabolism. J Clin Oncol 1997;15:1885-96.
-
(1997)
J Clin Oncol
, vol.15
, pp. 1885-1896
-
-
Busse, D.1
Busch, F.W.2
Bohnenstengel, F.3
-
40
-
-
0030916085
-
Nonlinear pharmacokinetics of cyclophosphamide and 4- hydroxycyclophosphamide/aldophosphamide in patients with metastatic breast cancer receiving high-dose chemotherapy followed by autologous bone-marrow transplantation
-
Chen TL, Kennedy MJ, Anderson LW, et al. Nonlinear pharmacokinetics of cyclophosphamide and 4-hydroxycyclophosphamide/aldophosphamide in patients with metastatic breast cancer receiving high-dose chemotherapy followed by autologous bone-marrow transplantation. Drug Metab Dispos 1997;25:544-51.
-
(1997)
Drug Metab Dispos
, vol.25
, pp. 544-551
-
-
Chen, T.L.1
Kennedy, M.J.2
Anderson, L.W.3
|