Down-regulation does not mediate natriuretic peptide-dependent desensitization of natriuretic peptide receptor (NPR)-A or NPR-B: Guanylyl cyclase-linked natriuretic peptide receptors do not internalize

Molecular Pharmacology

Volumn 67, Issue 1, 2005, Pages 174-183

  Fan, Danhua ^a   Bryan, Paula M ^a   Antos, Laura K ^a   Potthast, Regine J ^a   Potter, Lincoln R ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATRIAL NATRIURETIC FACTOR; BRAIN NATRIURETIC PEPTIDE; BRAIN NATRIURETIC PEPTIDE TYPE A; CYCLIC GMP; G PROTEIN COUPLED RECEPTOR; GUANYLATE CYCLASE; IODINE 125; LIGAND; NATRIURETIC PEPTIDE TYPE C; PHOSPHORAMIDON; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BIOTINYLATION; CONTROLLED STUDY; DESENSITIZATION; DOWN REGULATION; FRACTIONATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HORMONE BINDING; HUMAN; HUMAN CELL; IMMUNOASSAY; NONHUMAN; PARTITION COEFFICIENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEINASE INHIBITION; QUANTITATIVE ANALYSIS; RAT; SECOND MESSENGER; TEMPERATURE;

ATRIAL NATRIURETIC FACTOR; BIOLOGICAL TRANSPORT; CELL LINE; DNA, COMPLEMENTARY; DOWN-REGULATION; GLYCOPEPTIDES; GUANYLATE CYCLASE; HUMANS; IODINE RADIOISOTOPES; PROTEIN TRANSPORT; RECEPTORS, ATRIAL NATRIURETIC FACTOR; TRANSFECTION;

EID: 11244279891     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.104.002436     Document Type: Article

References (51)

1. Abbey SE and Potter LR (2002) Vasopressin-dependent inhibition of the C-type natriuretic peptide receptor, NPR-B/GC-B, requires elevated intracellular calcium concentrations. J Biol Chem 277:42423-42430.
2. Abe T, Arakawa Y, Rajasekaran AK, Yu TH, and Wada O (1995) Interaction of atrial natriuretic peptide with its receptors in bovine lung membranes. J Biol Chem 270:7672-7678.
3. Bryan PM and Potter LR (2002) The atrial natriuretic peptide receptor (NPR-A/GC-A) is dephosphorylated by distinct microcystin-sensitive and magnesium-dependent protein phosphatases. J Biol Chem 277:16041-16047.
4. Chinkers M and Garbers DL (1989) The protein kinase domain of the ANP receptor is required for signaling. Science (Wash DC) 245:1392-1394.
5. Chinkers M and Wilson EM (1992) Ligand-independent oligomerization of natriuretic peptide receptors. Identification of heteromeric receptors and a dominant negative mutant. J Biol Chem 267:18589-18597.
6. Cohen D, Koh GY, Nikonova LN, Porter JG, and Maack T (1996) Molecular determinants of the clearance function of type C receptors of natriuretic peptides. J Biol Chem 271:9863-9869.
7. De Lean A (1986) Amiloride potentiates atrial natriuretic factor inhibitory action by increasing receptor binding in bovine adrenal zona glomerulosa. Life Sci 39:1109-1116.
8. Duda T and Sharma RK (1990) Regulation of guanylate cyclase activity by atrial natriuretic factor and protein kinase C. Mol Cell Biochem 93:179-184.
9. El Kouhen R, Burd AL, Erickson-Herbrandson LJ, Chang CY, Law PY, and Loh HH (2001) Phosphorylation of Ser363, Thr370 and Ser375 residues within the carboxyl tail differentially regulates μ-opioid receptor internalization. J Biol Chem 276:12774-12780.
10. Foster DC and Garbers DL (1998) Dual role for adenine nucleotides in the regulation of the atrial natriuretic peptide receptor, guanylyl cyclase-A. J Biol Chem 273:16311-16318.
11. Gauquelin G, Schiffrin EL, and Garcia R (1991) Downregulation of glomerular and vascular atrial natriuretic factor receptor subtypes by angiotensin II. J Hypertens 9:1151-1160.
12. Huo X, Abe T, and Misono KS (1999) Ligand binding-dependent limited proteolysis of the atrial natriuretic peptide receptor: juxtamembrane hinge structure essential for transmembrane signal transduction. Biochemistry 38:16941-16951.
13. Jewett JR, Koller KJ, Goeddel DV, and Lowe DG (1993) Hormonal induction of low affinity receptor guanylyl cyclase. EMBO (Eur Mol Biol Organ) J 12:769-777.
14. Joubert S, Labrecque J, and De Lean A (2001) Reduced activity of the NPR-A kinase triggers dephosphorylation and homologous desensitization of the receptor. Biochemistry 40:11096-11105.
15. Katzmann DJ, Odorizzi G, and Emr SD (2002) Receptor downregulation and multivesicular-body sorting. Nat Rev Mol Cell Biol 3:893-905.
16. Kim SZ, Cho KW, and Kim SH (1999) Modulation of endocardial natriuretic peptide receptors in right ventricular hypertrophy. Am J Physiol 277:H2280-H2289.
17. Koh GY, Nussenzveig DR, Okolicany J, Price DA, and Maack T (1992) Dynamics of atrial natriuretic factor-guanylate cyclase receptors and receptor-ligand complexes in cultured glomerular mesangial and renomedullary interstitial cells. J Biol Chem 267:11987-11994.
18. Kurose H, Inagami T, and Ui M (1987) Participation of adenosine 5′-triphosphate in the activation of membrane-bound guanylate cyclase by the atrial natriuretic factor. FEBS Lett 219:375-379.
19. Labrecque J, Deschenes J, McNicoll N, and De Lean A (2001) Agonistic induction of a covalent dimer in a mutant of natriuretic peptide receptor-A documents a juxtamembrane interaction that accompanies receptor activation. J Biol Chem 276:8064-8072.
20. Labrecque J, Mc Nicoll N, Marquis M, and De Lean A (1999) A disulfide-bridged mutant of natriuretic peptide receptor-A displays constitutive activity. Role of receptor dimerization in signal transduction. J Biol Chem 274:9752-9759.
21. Lefkowitz RJ, Pierce KL, and Luttrell LM (2002) Dancing with different partners: protein kinase a phosphorylation of seven membrane-spanning receptors regulates their G protein-coupling specificity. Mol Pharmacol 62:971-974.
22. Levin ER, Gardner DG, and Samson WK (1998) Natriuretic peptides. N Engl J Med 339:321-328.
23. Matsumoto T, Wada A, Tsutamoto T, Omura T, Yokohama H, Ohnishi M, Nakae I, Takahashi M, and Kinoshita M (1999) Vasorelaxing effects of atrial and brain natriuretic peptides on coronary circulation in heart failure. Am J Physiol 276:H1935-H1942.
24. Meloche S, McNicoll N, Liu B, Ong H, and De Lean A (1988) Atrial natriuretic factor Rl receptor from bovine adrenal zona glomerulosa: purification, characterization and modulation by amiloride. Biochemistry 27:8151-8158.
25. Misono KS (2002) Natriuretic peptide receptor: structure and signaling. Mol Cell Biochem 230:49-60.
26. Nussenzveig DR, Lewicki JA, and Maack T (1990) Cellular mechanisms of the clearance function of type C receptors of atrial natriuretic factor. J Biol Chem 265:20952-20958.
27. Ogawa H, Qiu Y, Ogata CM, and Misono KS (2004) Crystal structure of hormone-bound atrial natriuretic peptide receptor extracellular domain: rotation mechanism for transmembrane signal transduction. J Biol Chem 279:28625-28631.
28. Pandey KN (1992) Kinetic analysis of internalization, recycling and redistribution of atrial natriuretic factor-receptor complex in cultured vascular smooth-muscle cells. Ligand-dependent receptor down-regulation. Biochem J 288:55-61.
29. Pandey KN (1993) Stoichiometric analysis of internalization, recycling and redistribution of photoaffinity-labeled guanylate cyclase/atrial natriuretic factor receptors in cultured murine Leydig tumor cells. J Biol Chem 268:4382-4390.
30. Pandey KN (2001) Dynamics of internalization and sequestration of guanylyl cyclase/atrial natriuretic peptide receptor-A. Can J Physiol Pharmacol 79:631-639.
31. Pandey KN, Inagami T, and Misono KS (1986) Atrial natriuretic factor receptor on cultured Leydig tumor cells: ligand binding and photoaffinity labeling. Biochemistry 25:8467-8472.
32. Pandey KN, Kumar R, Li M, and Nguyen H (2000) Functional domains and expression of truncated atrial natriuretic peptide receptor-A: the carboxyl-terminal regions direct the receptor internalization and sequestration in COS-7 cells. Mol Pharmacol 57:259-267.
33. Pandey KN, Nguyen HT, Sharma GD, Shi SJ, and Kriegel AM (2002) Ligand-regulated internalization, trafficking and down-regulation of guanylyl cyclase/ atrial natriuretic peptide receptor-A in human embryonic kidney 293 cells. J Biol Chem 277:4618-4627.
34. Potter LR (1998) Phosphorylation-dependent regulation of the guanylyl cyclase-linked natriuretic peptide receptor B: dephosphorylation is a mechanism of desensitization. Biochemistry 37:2422-2429.
35. Potter LR and Garbers DL (1992) Dephosphorylation of the guanylyl cyclase-A receptor causes desensitization. J Biol Chem 267:14531-14534.
36. Potter LR and Garbers DL (1994) Protein kinase C-dependent desensitization of the atrial natriuretic peptide receptor is mediated by dephosphorylation. J Biol Chem 269:14636-14642.
37. Potter LR and Hunter T (1998a) Identification and characterization of the major phosphorylation sites of the B-type natriuretic peptide receptor. J Biol Chem 273:15533-15539.
38. Potter LR and Hunter T (1998b) Phosphorylation of the kinase homology domain is essential for activation of the A-type natriuretic peptide receptor. Mol Cell Biol 18:2164-2172.
39. Potter LR and Hunter T (1999) A constitutively "phosphorylated" guanylyl cyclase-linked atrial natriuretic peptide receptor mutant is resistant to desensitization. Mol Biol Cell 10:1811-1820.
40. Potter LR and Hunter T (2001) Guanylyl cyclase-linked natriuretic peptide receptors: structure and regulation. J Biol Chem 276:6057-6060.
41. Rathinavelu A and Isom GE (1991) Differential internalization and processing of atrial-natriuretic-factor B and C receptor in PC12 cells. Biochem J 276:493-497.
42. Schulz S and Waldman SA (1999) The guanylyl cyclase family of natriuretic peptide receptors. Vitam Horm 57:123-151.
43. Sechi LA, Valentin JP, Griffin CA, Lee E, Bartoli E, Humphreys MH, and Schambelan M (1995) Receptors for atrial natriuretic peptide are decreased in the kidney of rats with streptozotocin-induced diabetes mellitus. J Clin Investig 95:2451-2457.
44. Silberbach M and Roberts CT Jr (2001) Natriuretic peptide signalling: molecular and cellular pathways to growth regulation. Cell Signal 13:221-231.
45. Stephenson SL and Kenny AJ (1987) The hydrolysis of alpha-human atrial natriuretic peptide by pig kidney microvillar membranes is initiated by endopeptidase-24.11. Biochem J 243:183-187.
46. Tremblay J, Desjardins R, Hum D, Gutkowska J, and Hamet P (2002) Biochemistry and physiology of the natriuretic peptide receptor guanylyl cyclases. Mol Cell Biochem 230:31-47.
47. Tsutamoto T, Kanamori T, Morigami N, Sugimoto Y, Yamaoka O, and Kinoshita M (1993) Possibility of downregulation of atrial natriuretic peptide receptor coupled to guanylate cyclase in peripheral vascular beds of patients with chronic severe heart failure. Circulation 87:70-75.
48. Vickery RG and von Zastrow M (1999) Distinct dynamin-dependent and -independent mechanisms target structurally homologous dopamine receptors to different endocytic membranes. J Cell Biol 144:31-43.
49. Vieira MA, Gao M, Nikonova LN, and Maack T (2001) Molecular and cellular physiology of the dissociation of atrial natriuretic peptide from guanylyl cyclase a receptors. J Biol Chem 276:36438-36445.
50. Wong SK, Ma CP, Foster DC, Chen AY, and Garbers DL (1995) The guanylyl cyclase-A receptor transduces an atrial natriuretic peptide/ATP activation signal in the absence of other proteins. J Biol Chem 270:30818-30822.
51. Yasunari K, Kohno M, Murakawa K, Yokokawa K, Horio T, and Takeda T (1992) Phorbol ester and atrial natriuretic peptide receptor response on vascular smooth muscle. Hypertension 19:314-319.