Diaphorase can metabolize some vasorelaxants to NO and eliminate NO scavenging effect of 2-phenyl-4,4,5,5,-tetramethylimidazoline-1-oxyl-3-oxide (PTIO)

Physiological Research

Volumn 53, Issue 6, 2004, Pages 615-620

  Bartik P ^a   Chalupsky K ^a,b   Vavruska L ^a   Muller, B ^c   Stoclet, J C ^b   Entlicher, G ^a  

^a CHARLES UNIVERSITY   (Czech Republic)

^b CNRS   (France)

^c UNIVERSITÉ DE BORDEAUX   (France)

Author keywords

2 phenyl 4,4,5,5, tetramethylimidazoline 1 oxyl 3 oxide (PTIO) reduction; Diaphorase; Formaldoxime metabolism; Glycerol trinitrate metabolism

Indexed keywords

2 PHENYL 4,4,5,5 TETRAMETHYLIMIDAZOLINE 1 OXYL 3 OXIDE; CITRULLINE; DIHYDROLIPOAMIDE DEHYDROGENASE; FLAVOPROTEIN; FORMALDOXIME; GLYCERYL TRINITRATE; N(G) NITROARGININE METHYL ESTER; NITRATE; NITRITE; NITROUS OXIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE DEHYDROGENASE; SCAVENGER; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG; VASODILATOR AGENT;

ARTICLE; BRAIN NUCLEUS; CHEMICAL REACTION; DRUG EFFECT; DRUG ELIMINATION; DRUG METABOLISM; ELECTRON SPIN RESONANCE; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME METABOLISM; NONHUMAN; REACTION ANALYSIS; VASODILATATION;

CYCLIC N-OXIDES; FREE RADICAL SCAVENGERS; IMIDAZOLES; NADPH DEHYDROGENASE; NITRIC OXIDE; NITROGLYCERIN; OXIMES; VASODILATOR AGENTS;

EID: 11244257041     PISSN: 08628408     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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