High viral loads despite absence of clinical and pathological findings in cats experimentally infected with feline coronavirus (FCoV) type I and in naturally FCoV-infected cats

Journal of Feline Medicine and Surgery

Volumn 6, Issue 2, 2004, Pages 69-81

  Meli, M ^a   Kipar, A ^b,c   Muller C ^a   Jenal, K ^a   Gonczi E ^a   Borel, N ^a   Gunn Moore, D ^d   Chalmers, S ^e   Lin, F ^e   Reinacher, M ^b   Lutz, H ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b JUSTUS LIEBIG UNIVERSITY   (Germany)

^c UNIVERSITY OF LIVERPOOL   (United Kingdom)

^d UNIVERSITY OF BRISTOL   (United Kingdom)

^e Intervet UK Ltd   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; CAT DISEASE; CLINICAL FEATURE; CONFERENCE PAPER; CONTROLLED STUDY; CORONAVIRUS; HISTOPATHOLOGY; NONHUMAN; RNA ISOLATION; SEROCONVERSION; VIRUS ISOLATION; VIRUS LOAD; VIRUS SHEDDING;

ANIMALIA; CORONAVIRUS; FELIDAE; FELINE CORONAVIRUS; FELIS CATUS;

EID: 11144358266     PISSN: 1098612X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jfms.2003.08.007     Document Type: Conference Paper

References (50)

1. Addie, D.D., Toth, S., Murray, G.D., Jarrett, O., 1995. Risk of feline infectious peritonitis in cats naturally infected with feline coronavirus. American Journal of Veterinary Research 56, 429-434.
2. Addie, D.D., Toth, S., Herrewegh, A.A., Jarrett, O., 1996. Feline coronavirus in the intestinal contents of cats with feline infectious peritonitis. Veterinary Record 139, 522-523.
3. Boretti, F.S., Leutenegger, C.M., Mislin, C., Hofmann-Lehmann, R., Konig, S., Schroff, M., Junghans, C., Fehr, D., Huettner, S.W., Habel, A., Flynn, J.N., Aubert, A., Pedersen, N.C., Wittig, B., Lutz, H., 2000. Protection against FIV challenge infection by genetic vaccination using minimalistic DNA constructs for FIV env gene and feline IL-12 expression. Aids 14, 1749-1757.
4. Chalmers, W.S., Horsburgh, B.C., Baxendale, W., Brown, T.D., 1993. Enhancement of FIP in cats immunised with vaccinia virus recombinants expressing CCV and TGEV spike glycoproteins. Advances in Experimental Medicine & Biology 342, 359-364.
5. Egberink, H.F., Herrewegh, A.P., Schuurman, N.M., van der Linde-Sipman, J.S., Horzinek, M.C., de Groot, R.J., 1995. FIP, easy to diagnose?. Veterinary Quarterly 17(Suppl 1), S24-25.
6. Fehr, D., Bolla, S., Herrewegh, A.A., Horzinek, M.C., Lutz, H., 1996. [Detection of feline coronavirus using RT-PCR: basis for the study of the pathogenesis of feline infectious peritonitis (FIP)]. Schweizer Archiv für Tierheilkunde 138, 74-79.
7. Fehr, D., Holznagel, E., Bolla, S., Hauser, B., Herrewegh, A.A., Horzinek, M.C., Lutz, H., 1997. Placebo-controlled evaluation of a modified life virus vaccine against feline infectious peritonitis: safety and efficacy under field conditions. Vaccine 15, 1101-1109.
8. Fiscus, S.A., Rivoire, B.L., Teramoto, Y.A., 1987. Epitope-specific antibody responses to virulent and avirulent feline infectious peritonitis virus isolates. Journal of Clinical Microbiology 25, 1529-1534.
9. Foley, J.E., Poland, A., Carlson, J., Pedersen, N.C., 1997. Patterns of feline coronavirus infection and fecal shedding from cats in multiple-cat environments. Journal of the American Veterinary Medical Association 210, 1307-1312.
10. Glansbeek, H.L., Haagmans, B.L., te Lintelo, E.G., Egberink, H.F., Duquesne, V., Aubert, A., Horzinek, M.C., Rottier, P.J., 2002. Adverse effects of feline IL-12 during DNA vaccination against feline infectious peritonitis virus. Journal of General Virology 83, 1-10.
11. Gunn-Moore, D.A., Gruffydd-Jones, T.J., Harbour, D.A., 1998. Detection of feline coronaviruses by culture and reverse transcriptase-polymerase chain reaction of blood samples from healthy cats and cats with clinical feline infectious peritonitis. Veterinary Microbiology 62, 193-205.
12. Gut, M., 1999. Kombination von Frühabsetzen und Vakzinierung mit Primucell FIP: Evaluation der Wirksamkeit zur Verhinderung der Felinen Infektiösen Peritonitis der Katze in einer Feldstudie, in: Diss Uni Zurich, University of Zurich, Zurich.
13. Gut, M., Leutenegger, C.M., Huder, J.B., Pedersen, N.C., Lutz, H., 1999. One-tube fluorogenic reverse transcription-polymerase chain reaction for the quantisation of feline coronaviruses. Journal of Virological Methods 77, 37-46.
14. Harpold, L.M., Legendre, A.M., Kennedy, M.A., Plummer, P.J., Millsaps, K., Rohrbach, B., 1999. Fecal shedding of feline coronavirus in adult cats and kittens in an Abyssinian cattery. Journal of the American Veterinary Medical Association 215, 948-951.
15. Herrewegh, A.A., de Groot, R.J., Cepica, A., Egberink, H.F., Horzinek, M.C., Rottier, P.J., 1995. Detection of feline coronavirus RNA in feces, tissues, and body fluids of naturally infected cats by reverse transcriptase PCR. Journal of Clinical Microbiology 33, 684-689.
16. Herrewegh, A.A., Mahler, M., Hedrich, H.J., Haagmans, B.L., Egberink, H.F., Horzinek, M.C., Rottier, P.J., de Groot, R.J., 1997. Persistence and evolution of feline coronavirus in a closed cat-breeding colony. Virology 234, 349-363.
17. Herrewegh, A.A., Smeenk, I., Horzinek, M.C., Rottier, P.J., de Groot, R.J., 1998. Feline coronavirus type II strains 79-1683 and 79-1146 originate from a double recombination between feline coronavirus type I and canine coronavirus. Journal of Virology 72, 4508-4514.
18. Hofmann-Lehmann, R., Huder, J.B., Gruber, S., Boretti, F., Sigrist, B., Lutz, H., 2001. Feline leukaemia provirus load during the course of experimental infection and in naturally infected cats. Journal of General Virology 82, 1589-1596.
19. Hohdatsu, T., Okada, S., Koyama, H., 1991a. Characterization of monoclonal antibodies against feline infectious peritonitis virus type II and antigenic relationship between feline, porcine, and canine coronaviruses. Archives of Virology 117, 85-95.
20. Hohdatsu, T., Sasamoto, T., Okada, S., Koyama, H., 1991b. Antigenic analysis of feline coronaviruses with monoclonal antibodies (MAbs): preparation of MAbs which discriminate between FIPV strain 79-1146 and FECV strain 79-1683. Veterinary Microbiology 28, 13-24.
21. Hohdatsu, T., Okada, S., Ishizuka, Y., Yamada, H., Koyama, H., 1992. The prevalence of types I and II feline coronavirus infections in cats. Journal of Veterinary Medical Science 54, 557-562.
22. Horzinek, M.C., Lutz, H., 2000. An update on feline infectious peritonitis. Veterinary Sciences Tomorrow 1, 1-10.
23. Jacobse-Geels, H.E., Daha, M.R., Horzinek, M.C., 1982. Antibody, immune complexes, and complement activity fluctuations in kittens with experimentally induced feline infectious peritonitis. American Journal of Veterinary Research 43, 666-670.
24. Kennedy, M., Boedeker, N., Gibbs, P., Kania, S., 2001. Deletions in the 7a ORF of feline coronavirus associated with an epidemic of feline infectious peritonitis. Veterinary Microbiology 81, 227-234.
25. Kipar, A., Bellmann, S., Gunn-Moore, D.A., Leukert, W., Kohler, K., Menger, S., Reinacher, M., 1999. Histopathological alterations of lymphatic tissues in cats without feline infectious peritonitis after long-term exposure to FIP virus. Veterinary Microbiology 69, 131-137.
26. Kipar, A., Kohler, K., Leukert, W., Reinacher, M., 2001a. A comparison of lymphatic tissues from cats with spontaneous feline infectious peritonitis (FIP), cats with FIP virus infection but no FIP, and cats with no infection. Journal of Comparative Pathology 125, 182-191.
27. Kipar, A., Leutenegger, C.M., Hetzel, U., Akens, M.K., Mislin, C.N., Reinacher, M., Lutz, H., 2001b. Cytokine mRNA levels in isolated feline monocytes. Veterinary Immunology & Immunopathology 78, 305-315.
28. Kipar, A., May, H., Menger, S., Weber, M., Leukert, W., Reinacher, M., 2003. Granulomatous vasculitis in feline infectious peritonitis: crosstalk between activated monocytes and endothelial cells. Veterinary Pathology. submitted for publication.
29. Leutenegger, C.M., Klein, D., Hofmann-Lehmann, R., Mislin, C., Hummel, U., Boni, J., Boretti, F., Guenzburg, W.H., Lutz, H., 1999a. Rapid feline immunodeficiency virus provirus quantitation by polymerase chain reaction using the TaqMan fluorogenic real-time detection system. Journal of Virological Methods 78, 105-116.
30. Leutenegger, C.M., Mislin, C.N., Sigrist, B., Ehrengruber, M.U., Hofmann-Lehmann, R., Lutz, H., 1999b. Quantitative real-time PCR for the measurement of feline cytokine mRNA. Veterinary Immunology & Immunopathology 71, 291-305.
31. Osterhaus, A.D., Horzinek, M.C., Reynolds, D.J., 1977. Seroepidemiology of feline infectious peritonitis virus infections using transmissible gastroenteritis virus as antigen. Zentralblatt für Veterinärmedizin [B] 24, 835-841.
32. Pedersen, N.C., 1976. Serologic studies of naturally occurring feline infectious peritonitis. American Journal of Veterinary Research 37, 1449-1453.
33. Pedersen, N.C., Boyle, J.F., Floyd, K., 1981a. Infection studies in kittens, using feline infectious peritonitis virus propagated in cell culture. American Journal of Veterinary Research 42, 363-367.
34. Pedersen, N.C., Boyle, J.F., Floyd, K., Fudge, A., Barker, J., 1981b. An enteric coronavirus infection of cats and its relationship to feline infectious peritonitis. American Journal of Veterinary Research 42, 368-377.
35. Pedersen, N.C., Black, J.W., Boyle, J.F., Evermann, J.F., McKeirnan, A.J., Ott, R.L., 1984a. Pathogenic differences between various feline coronavirus isolates. Advances in Experimental Medicine & Biology 173, 365-380.
36. Pedersen, N.C., Evermann, J.F., McKeirnan, A.J., Ott, R.L., 1984b. Pathogenicity studies of feline coronavirus isolates 79-1146 and 79-1683. American Journal of Veterinary Research 45, 2580-2585.
37. Pedersen, N.C., Floyd, K., 1985. Experimental studies with three new strains of feline infectious peritonitis virus: FIPV-UCD2, FIPV-UCD3, and FIPV-UCD4. Compendium on Continuing Education 7, 1001-1011.
38. Pedersen, N.C., 1995. An overview of feline enteric coronavirus and infectious peritonitis virus infections. Feline Practice 23, 7-21.
39. Poland, A.M., Vennema, H., Foley, J.E., Pedersen, N.C., 1996. Two related strains of feline infectious peritonitis virus isolated from immunocompromised cats infected with a feline enteric coronavirus. Journal of Clinical Microbiology 34, 3180-3184.
40. Posch, A., Posch, U., Kuebber-Heiss, A., Stur, I., Seiser, M., Moestl, K., 2001. Feline coronaviruses: differentiation of the types I and II by RT-PCR and their ocurrence in Austrian cat populations. Wiener Tierärzliche Monatschrift 88, 1-9.
41. Schroo, S., 1994. Kompetitiver ELISA zum Nachweis von löslichen Immunkomplexen in Serum und Exsudaten FIP-verdächtiger Katzen, in: Vet. Med. Diss, Justus Liebig University Giessen, Giessen.
42. Simons, F., Rofina, J., Rottier, P.J., Vennema, H., Pol, J.M.A., Egberink, H.F., 2002. Detection of replicating feline coronavirus in peripheral blood mononuclear cells as a potential diagnostic assay for feline infectious peritonitis, in: Second International FCoV/FIP Symposium, Glasgow.
43. Stoddart, C.A., Scott, F.W., 1989. Intrinsic resistance of feline peritoneal macrophages to coronavirus infection correlates with in vivo virulence. Journal of Virology 63, 436-440.
44. Stoddart, M.E., Gaskell, R.M., Harbour, D.A., Pearson, G.R., 1988. The sites of early viral replication in feline infectious peritonitis. Veterinary Microbiology 18, 259-271.
45. Vennema, H., de Groot, R.J., Harbour, D.A., Dalderup, M., Gruffydd-Jones, T., Horzinek, M.C., Spaan, W.J., 1990. Early death after feline infectious peritonitis virus challenge due to recombinant vaccinia virus immunization. Journal of Virology 64, 1407-1409.
46. Vennema, H., Poland, A., Foley, J., Pedersen, N.C., 1998. Feline infectious peritonitis viruses arise by mutation from endemic feline enteric coronaviruses. Virology 243, 150-157.
47. Vogtlin, A., Fraefel, C., Albini, S., Leutenegger, C.M., Schraner, E., Spiess, B., Lutz, H., Ackermann, M., 2002. Quantification of feline herpesvirus 1 DNA in ocular fluid samples of clinically diseased cats by real-time TaqMan PCR. Journal of Clinical Microbiology 40, 519-523.
48. Ward, J.M., 1970. Morphogenesis of a virus in cats with experimental feline infectious peritonitis. Virology 41, 191-194.
49. Wasmoen, T.L., Kadakia, N.P., Unfer, R.C., Fickbohm, B.L., Cook, C.P., Chu, H.J., Acree, W.M., 1995. Protection of cats from infectious peritonitis by vaccination with a recombinant raccoon poxvirus expressing the nucleocapsid gene of feline infectious peritonitis virus. Advances in Experimental Medicine & Biology 380, 221-228.
50. Weiss, R.C., Scott, F.W., 1981. Antibody-mediated enhancement of disease in feline infectious peritonitis: comparisons with dengue hemorrhagic fever. Comparative Immunology, Microbiology & Infectious Diseases 4, 175-189.