Scintigraphic Evaluation of a Novel Colon-Targeted Delivery System (CODES™) in Healthy Volunteers

Journal of Pharmaceutical Sciences

Volumn 93, Issue 5, 2004, Pages 1287-1299

  Katsuma, Masataka ^a   Watanabe, Shunsuke ^a   Takemura, Shigeo ^a   Sako, Kazuhiro ^a   Sawada, Toyohiro ^a   Masuda, Yoshinori ^a   Nakamura, Katsutoshi ^a   Fukui, Muneo ^a   Connor, Alyson L ^b   Wilding, Ian R ^b  

^a ASTELLAS PHARMA INC   (Japan)

^b PHARMACEUTICAL PROFILES LTD   (United Kingdom)

Author keywords

Colonic drug delivery; Disintegration profile; Food effects; Gastrointestinal transit; Human; Lactulose; Scintigraphy

Indexed keywords

CALCIUM PHOSPHATE DIBASIC; CELLULOSE; CITRIC ACID TRIETHYL ESTER; EUDRAGIT; HYDROXYPROPYLMETHYLCELLULOSE; LACTULOSE; MAGNESIUM STEARATE; MICROCRYSTALLINE CELLULOSE; POLACRILIN; POVIDONE; TALC;

ADULT; ARTICLE; CLINICAL TRIAL; COLON; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DRUG COATING; DRUG DELIVERY SYSTEM; FOOD DRUG INTERACTION; GASTROINTESTINAL TRANSIT; HUMAN; HUMAN EXPERIMENT; ISOTOPE LABELING; MALE; NORMAL HUMAN; TABLET DISINTEGRATION TIME;

EID: 11144357710     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1002/jps.20063     Document Type: Article

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