Loss of heterozygosity on 10q and mutational status of PTEN and BMPRIA in colorectal primary tumours and metastases

British Journal of Cancer

Volumn 90, Issue 6, 2004, Pages 1230-1234

  Karoui, M ^a,c,e   Tresallet, C ^a,f   Julie, C ^a   Zimmermann, U ^a   Staroz, F ^a   Brams, A ^a,c   Muti, C ^b   Boulard, C ^c   Robreau, A M ^d   Puy, H ^a,d   Malafosse, R ^a   Penna, C ^a   Pruvot, F R ^e   Thiery, J P ^c   Boileau, C ^a   Rougier, P ^a   Nordlinger, B ^a   Radvanyi, F ^c   Franc, B ^a   Hofmann Radvanyi, H ^a,c  

^a LABORATOIRE DES SCIENCES DU CLIMAT ET DE L ENVIRONNEMENT   (France)

^b HÔPITAL AMBROISE PARÉ   (France)

^c INSTITUT CURIE   (France)

^d HÔPITAL LOUIS MOURIER   (France)

^e LILLE UNIVERSITY HOSPITAL   (France)

^f PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

Author keywords

BMPRIA; Chromosome 10; Colorectal cancer; LOH; Metastasis; PTEN

Indexed keywords

PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE;

ADULT; AGED; ALLELE; ARTICLE; BMPR1A GENE; CHROMOSOME 10Q; CLINICAL ARTICLE; COLORECTAL CANCER; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; GENE; GENE CONTROL; GENE DELETION; GENE INACTIVATION; GENE LOCATION; GENE LOSS; GENE MUTATION; HETEROZYGOSITY LOSS; HETEROZYGOTE; HUMAN; MALE; METASTASIS; MICROSATELLITE INSTABILITY; PRIORITY JOURNAL; PROMOTER REGION;

BASE SEQUENCE; BONE MORPHOGENETIC PROTEIN RECEPTORS, TYPE I; CHROMOSOMES, HUMAN, PAIR 10; COLORECTAL NEOPLASMS; GENES, TUMOR SUPPRESSOR; GERM-LINE MUTATION; HUMANS; LOSS OF HETEROZYGOSITY; MICROSATELLITE REPEATS; MOLECULAR SEQUENCE DATA; NEOPLASM METASTASIS; PHOSPHORIC MONOESTER HYDROLASES; PROTEIN-SERINE-THREONINE KINASES; PTEN PHOSPHOHYDROLASE; RECEPTORS, GROWTH FACTOR; TUMOR SUPPRESSOR PROTEINS;

EID: 11144354308     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjc.6601687     Document Type: Article

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