The functional shift of endothelin receptor subtypes in doqs with heart failure produced by rapid ventricular pacing

Journal of Cardiovascular Pharmacology

Volumn 44, Issue SUPPL. 1, 2004, Pages

  Tadano, Kiyoshi ^a   Hosokawa, Akio ^a   Fukuroda, Takahiro ^a   Nishikibe, Masaru ^a  

^a BANYU PHARMACEUTICAL CO LTD   (Japan)

Author keywords

Dogs; Endothelin; Heart failure; Receptors

Indexed keywords

ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; ENDOTHELIN B RECEPTOR; ENDOTHELIN B RECEPTOR AGONIST; ENDOTHELIN RECEPTOR AGONIST; SARAFOTOXIN S6C;

ANIMAL MODEL; ANIMAL TISSUE; ATTENUATION; CONFERENCE PAPER; CONGESTIVE HEART FAILURE; CONTROLLED STUDY; DOG; HEART LEFT VENTRICLE; HEART MUSCLE CONTRACTILITY; HEART OUTPUT; HEART VENTRICLE PACING; LUNG VASCULAR RESISTANCE; LUNG VASOCONSTRICTION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION;

ANIMALS; CARDIAC OUTPUT; CARDIAC PACING, ARTIFICIAL; DISEASE MODELS, ANIMAL; DOGS; ENDOTHELIN-1; HEART FAILURE; LUNG; MALE; MYOCARDIAL CONTRACTION; MYOCARDIUM; RECEPTOR, ENDOTHELIN A; RECEPTOR, ENDOTHELIN B; UP-REGULATION; VASCULAR RESISTANCE; VASOCONSTRICTION; VENTRICULAR PRESSURE; VIPER VENOMS;

EID: 11144342046     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.fjc.0000166291.72324.eb     Document Type: Conference Paper

References (13)

1. Cody RJ, Haas GJ, Binkley PF, et al. Plasma endothelin correlates with the extent of pulmonary hypertension in patients with chronic congestive heart failure. Circulation. 1992;85:504-509.
2. Mulder P, Richard V, Derumeaux G, et al. Role of endogenous endothelin in chronic heart failure: effect of long-term treatment with an endothelin antagonist on survival, hemodynamics, and cardiac remodeling. Circulation. 1997;96:1976-1982.
3. Tadano K, Suzuki J, Hanada K, et al. Pathophysiological roles of endogenous endothelin-1 in dogs with chronic heart failure produced by rapid right ventricular pacing. J Phamacol Exp Ther. 2001;298:729-736.
4. Calderone A, Rouleau JL, de Champlain J, et al. Regulation of the endothelin-1 transmembrane signaling pathway: the potential role of agonist-induced desensitization in the coronary artery of the rapid ventricular pacing-overdrive dog model of heart failure. J Mol Cell Cardiol. 1993;25:895-903.
5. LeMonnier de Gouville AC, Lippton H, Cohen G, et al. Vasodilator activity of endothelin-1 and endothelin-3: rapid development of cross-tachyphylaxis and dependence on the rate of endothelin administration. J Pharmacol Exp Ther. 1990;254:1024-1028.
6. Li K, Rouleau JL. Altered responsiveness to endothelin-1 of myocardium from pacing-induced heart failure model in the dog. Cardiovasc Drugs Ther. 1996;10:107-112.
7. Thomas PB, Liu ECK, Webb ML, et al. Exogenous effects and endogenous production of endothelin in cardiac myocytes: potential significance in heart failure. Am J Physiol. 1996;271:H2629-H2637.
8. Sakai S, Miyauchi T, Sakurai T, et al. Endogenous endothelin-1 participates in the maintenance of cardiac function in rats with congestive heart failure. Circulation. 1996;93:1214-1222.
9. Asano K, Bohlmeyer TJ, Westcott JY, et al. Altered expression of endothelin receptors in failing human left ventricles. J Mol Cell Cardiol. 2002;34:833-846.
10. Zolk O, Quattek J, Sitzler G, et al. Expression of endothelin-1, endothelin-converting enzyme, and endothelin receptors in chronic heart failure. Circulation. 1999;99:2118-2123.
11. Fu L-X, Sun X-Y, Hender T, et al. Decreased density of mesenteric arteries but not of myocardial endothelin receptors and function in rats with chronic ischemic heart failure. J Cardiovasc Pharmacol. 1993;22:177-182.
12. Cavero PG, Miller WL, Heublein DM, et al. Endothelin in experimental congestive heart failure in the anesthetized dog. Am J Physiol. 1990;259:F312-F317.
13. Cody RJ, Haas GJ, Binkley PF, et al. Plasma endothelin correlates with the extent of pulmonary hypertension in patients with chronic congestive heart failure. Circulation. 1992;85:504-509.