Metabolism, pharmacokinetics, tissue distribution, and excretion of [ 14C]CP-424391 in rats

Drug Metabolism and Disposition

Volumn 33, Issue 1, 2005, Pages 190-199

  Khojasteh Bakht, S Cyrus ^a   O'Donnell, John P ^b   Fouda, Hassan G ^d   Potchoiba, Michael J ^b,c  

^a Depts of Pharmacokin and Metab   (United States)

^b PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United States)

^c PFIZER INC   (United States)

^d NONE

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINO N (BENZYL 2 METHYL 3 OXO 2,3,3A,4,6,7 HEXAHYDROPYRAZOLO[4,3 C]PYRIDIN 5 YLBENZYLOXYMETHYL 2 OXOETHYL)ISOBUTYRAMIDE; BENZYL DERIVATIVE; CAPROMORELIN; CARBON 14; GROWTH HORMONE SECRETAGOGUE; O BENZYLSERINE; PYRAZOLE DERIVATIVE; PYRAZOLIDINE; SERINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CENTRAL NERVOUS SYSTEM; CIRCULATION; CONTROLLED STUDY; DEBENZYLATION; DEMETHYLATION; DRUG ABSORPTION; DRUG DISPOSITION; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG EXCRETION; DRUG HALF LIFE; DRUG METABOLISM; DRUG OXIDATION; DRUG TISSUE LEVEL; FECES; FEMALE; HEMOCONCENTRATION; ISOTOPE LABELING; LIVER; MALE; NONHUMAN; PRIORITY JOURNAL; RADIOACTIVITY; SEX DIFFERENCE; SKIN; TIME; URINARY EXCRETION; UVEA;

ADMINISTRATION, ORAL; ANIMALS; CARBON RADIOISOTOPES; FECES; FEMALE; GROWTH SUBSTANCES; MALE; PIPERIDINES; PYRAZOLES; RATS; RATS, LONG-EVANS; RATS, SPRAGUE-DAWLEY; TISSUE DISTRIBUTION;

ANIMALIA;

EID: 11144336036     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: 10.1124/dmd.104.001065     Document Type: Article

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