Beneficial effects of isonicotinoylhydrazones on isoniazid-induced disruption of ecological oxidative balance [2]

Medical Hypotheses

Volumn 64, Issue 3, 2005, Pages 662-

  Georgieva, N ^a   Gadjeva, V ^b  

^a Faculty of Veterinary Medicine   (Bulgaria)

^b TRAKIA UNIVERSITY   (Bulgaria)

Author keywords

[No Author keywords available]

Indexed keywords

CATALASE; ISONIAZID DERIVATIVE; MALONALDEHYDE; N ISONICOTINOYL N' (2 HYDROXY 4 ETHOXYBENZAL)HYDRAZONE; N ISONICOTINOYL N' (2,3 DICHLORO 2 HYDROXYBENZAL)HYDRAZONE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

DRUG EFFECT; ENZYME ACTIVITY; LETTER; LIPID PEROXIDATION; LIVER HOMOGENATE; NONHUMAN; OXIDATION; PRIORITY JOURNAL;

ANIMALS; ANTIOXIDANTS; ECOLOGY; ISONIAZID; MICE; MODELS, BIOLOGICAL; OXIDATION-REDUCTION; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES;

EID: 11144304534     PISSN: 03069877     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mehy.2004.09.010     Document Type: Letter

References (5)

1. E. Albano, and A. Tomasi Spin trapping of free radical intermediates prodused during the metabolism of isoniazid and iproniazid in isolated hepatocytes Biochem Pharmacol 36 18 1987 2913 2920
2. J.Y. Wang, R.M. Burger, and K. Drlica Role of superoxide in catalase-peroxidase-mediated isoniazid action against mycobacteria Antimicrob Agents Ch 42 1998 709 711
3. N. Georgieva, V. Gadjeva, A. Tolekova, and D. Dimitrov New isonicotinoylhydrazones with SSA protect against oxidative-hepatic injury of izoniazid Trakia J Sci 2 2004 37 43
4. S. Varbanova, and N. Georgieva New isonicotinoylhydrazones with tuberculostatic action Vet Sci 27 1 1993 81 85 [in Bulgarian]
5. N. Georgieva, and V. Gadjeva Isonicotinoylhydrazone analogs of isoniazid: relationship between superoxide scavenging and tuberculostatic activities Biochemistry (Moscow) 67 5 2002 588 591