Mapping the interaction of bradykinin 1-5 with the exodomain of human protease activated receptor 4

FEBS Letters

Volumn 579, Issue 1, 2005, Pages 25-29

  Nieman, Marvin T ^a,b   Pagan Ramos, Eileen ^b   Warnock, Mark ^a,b   Krijanovski, Yelena ^a   Hasan, Ahmed A K ^b   Schmaier, Alvin H ^a,b  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b Thromgen Inc   (United States)

Author keywords

Bradykinin; Bradykinin 1 5; PAR4; RPPGF; Thrombin

Indexed keywords

ARGININE; BRADYKININ DERIVATIVE; BRADYKININ[1-5]; MUTANT PROTEIN; PROLINE; PROTEINASE ACTIVATED RECEPTOR 4; THROMBIN; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; DRUG RECEPTOR BINDING; ENZYME DEGRADATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; THROMBOCYTE AGGREGATION; WILD TYPE;

BINDING, COMPETITIVE; BIOTIN; BRADYKININ; HUMANS; PEPTIDE FRAGMENTS; PROTEIN INTERACTION MAPPING; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, THROMBIN; RECOMBINANT PROTEINS; THROMBIN;

EID: 11144291216     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2004.11.041     Document Type: Article

References (22)

1. M.L. Kahn, M. Nakanishi-Matsui, M.J. Shapiro, H. Ishihara, and S.R. Coughlin Protease-activated receptors 1 and 4 mediate activation of human platelets by thrombin J. Clin. Invest. 103 1999 879 887
2. S. Swift, P.J. Sheridan, L. Covic, and A. Kuliopulos PAR1 thrombin receptor-G protein interactions. Separation of binding and coupling determinants in the galpha subunit J. Biol. Chem. 275 2000 2627 2635
3. S. Verrall, M. Ishii, M. Chen, L. Wang, T. Tram, and S.R. Coughlin The thrombin receptor second cytoplasmic loop confers coupling to Gq-like G proteins in chimeric receptors. Additional evidence for a common transmembrane signaling and G protein coupling mechanism in G protein-coupled receptors J. Biol. Chem. 272 1997 6898 6902
4. S.R. Coughlin How the protease thrombin talks to cells Proc. Natl. Acad. Sci. USA 96 1999 11023 11027
5. L.F. Brass Thrombin and platelet activation Chest 124 2003 18S 25S
6. L. Covic, A.L. Gresser, and A. Kuliopulos Biphasic kinetics of activation and signaling for PAR1 and PAR4 thrombin receptors in platelets Biochemistry 39 2000 5458 5467
7. M.J. Shapiro, E.J. Weiss, T.R. Faruqi, and S.R. Coughlin Protease-activated receptors 1 and 4 are shut off with distinct kinetics after activation by thrombin J. Biol. Chem. 275 2000 25216 25221
8. L. Covic, M. Misra, J. Badar, C. Singh, and A. Kuliopulos Pepducin-based intervention of thrombin-receptor signaling and systemic platelet activation Nat. Med. 8 2002 1161 1165
9. C.K. Derian, B.P. Damiano, M.F. Addo, A.L. Darrow, M.R. D'Andrea, M. Nedelman, H.C. Zhang, B.E. Maryanoff, and P. Andrade-Gordon Blockade of the thrombin receptor protease-activated receptor-1 with a small-molecule antagonist prevents thrombus formation and vascular occlusion in nonhuman primates J. Pharmacol. Exp. Ther. 304 2003 855 861
10. Y. Kato, Y. Kita, Y. Hirasawa-Taniyama, M. Nishio, K. Mihara, K. Ito, T. Yamanaka, J. Seki, S. Miyata, and S. Mutoh Inhibition of arterial thrombosis by a protease-activated receptor 1 antagonist, FR171113, in the guinea pig Eur. J. Pharmacol. 473 2003 163 169
11. A.A. Hasan, M. Warnock, M. Nieman, S. Srikanth, F. Mahdi, R. Krishnan, A. Tulinsky, and A.H. Schmaier Mechanisms of Arg-Pro-Pro-Gly-Phe inhibition of thrombin Am. J. Physiol Heart Circ. Physiol. 285 2003 H183 H193
12. M.T. Nieman, M. Warnock, A.A. Hasan, F. Mahdi, B.R. Lucchesi, N.J. Brown, L.J. Murphey, and A.H. Schmaier The preparation and characterization of novel peptide antagonists to thrombin and factor VIIa and activation of protease-activated receptor 1 J. Pharmacol. Exp. Ther. 311 2004 492 501
13. M. Nakanishi-Matsui, Y.W. Zheng, D.J. Sulciner, E.J. Weiss, M.J. Ludeman, and S.R. Coughlin PAR3 is a cofactor for PAR4 activation by thrombin Nature 404 2000 609 613
14. A.A. Hasan, D.B. Cines, J. Zhang, and A.H. Schmaier The carboxyl terminus of bradykinin and amino terminus of the light chain of kininogens comprise an endothelial cell binding domain J. Biol. Chem. 269 1994 31822 31830
15. W.F. Xu, H. Andersen, T.E. Whitmore, S.R. Presnell, D.P. Yee, A. Ching, T. Gilbert, E.W. Davie, and D.C. Foster Cloning and characterization of human protease-activated receptor 4 Proc. Natl. Acad. Sci. USA 95 1998 6642 6646
16. A.A. Hasan, S. Amenta, and A.H. Schmaier Bradykinin and its metabolite, Arg-Pro-Pro-Gly-Phe, are selective inhibitors of alpha-thrombin-induced platelet activation Circulation 94 1996 517 528
17. D.B. Cleary, W.D. Ehringer, and M.C. Maurer Establishing the inhibitory effects of bradykinin on thrombin Arch. Biochem. Biophys. 410 2003 96 106
18. T.K. Vu, D.T. Hung, V.I. Wheaton, and S.R. Coughlin Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation Cell 64 1991 1057 1068
19. D.B. Cleary, T.A. Trumbo, and M.C. Maurer Protease-activated receptor 4-like peptides bind to thrombin through an optimized interaction with the enzyme active site surface Arch. Biochem. Biophys. 403 2002 179 188
20. I.I. Mathews, K.P. Padmanabhan, V. Ganesh, A. Tulinsky, M. Ishii, J. Chen, C.W. Turck, S.R. Coughlin, and J.W. Fenton Crystallographic structures of thrombin complexed with thrombin receptor peptides: existence of expected and novel binding modes Biochemistry 33 1994 3266 3279
21. O.V. Mitkevich, J.R. Shainoff, P.M. Dibello, V.C. Yee, D.C. Teller, G.B. Smejkal, P.D. Bishop, I.S. Kolotushkina, K. Fickenscher, and G.P. Samokhin Coagulation factor XIIIa undergoes a conformational change evoked by glutamine substrate. Studies on kinetics of inhibition and binding of XIIIA by a cross-reacting antifibrinogen antibody J. Biol. Chem. 273 1998 14387 14391
22. S. Kadono, A. Sakamoto, Y. Kikuchi, M. Oh-Eda, N. Yabuta, T. Koga, K. Hattori, T. Shiraishi, M. Haramura, H. Kodama, T. Esaki, H. Sato, Y. Watanabe, S. Itoh, M. Ohta, and T. Kozono Crystal structure of human factor VIIa/tissue factor in complex with peptide mimetic inhibitor Biochem. Biophys. Res. Commun. 324 2004 1227 1233