Single-isomer R-salbutamol is not superior to racemate regarding protection for bronchial hyperresponsiveness

Respiratory Medicine

Volumn 98, Issue 10, 2004, Pages 990-999

  Sjöswärd, Kerstin Naidu ^a   Hmani, Mounira ^b,c   Davidsson, Anette ^e   Söderkvist, Peter ^c   Schmekel, Birgitta ^d  

^a LINKÖPING UNIVERSITY HOSPITAL   (Sweden)

^b UNIVERSITY OF SFAX   (Tunisia)

^c Fac Hlth Sci   (Sweden)

^d Fac Hlth S   (Sweden)

^e NONE

Author keywords

Asthma; Bronchial hyperresponsiveness; Enantiomer; IOS; Salbutamol

Indexed keywords

CORTICOSTEROID; LEVALBUTEROL; SALBUTAMOL;

ADULT; ARTICLE; ASTHMA; BRONCHUS HYPERREACTIVITY; CLINICAL ARTICLE; CLINICAL TRIAL; COLD AIR; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DISEASE SEVERITY; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG MECHANISM; DRUG RESPONSE; DRUG STRUCTURE; DRUG WITHDRAWAL; FEMALE; FORCED EXPIRATORY VOLUME; GENOTYPE; HUMAN; HYPERVENTILATION; INHALATION TEST; ISOMER; LUNG FUNCTION TEST; MALE; MEDICAL NEBULIZER; OSCILLOMETRY; PRIORITY JOURNAL; RACEMIC MIXTURE; RANDOMIZED CONTROLLED TRIAL; STATISTICAL SIGNIFICANCE; STRUCTURE ANALYSIS;

ADULT; ALBUTEROL; BRONCHI; BRONCHODILATOR AGENTS; CROSS-OVER STUDIES; DOUBLE-BLIND METHOD; FEMALE; FORCED EXPIRATORY VOLUME; GENOTYPE; HUMANS; MALE; MIDDLE AGED; POLLEN; STEREOISOMERISM; TIME FACTORS;

EID: 11144272224     PISSN: 09546111     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.rmed.2004.03.005     Document Type: Article

References (35)

1. Waldeck B. Beta-Adrenoceptor agonists and asthma-100 years of development Eur J Pharmacol 445 2002 1-12
2. Schmekel B. Rydberg I. Norlander B. et al. Stereoselective pharmacokinetics of S-salbutamol after administration of the racemate in healthy volunteers Eur Respir J 13 1999 1230-1235
3. Gleich G.J. Jacoby D.B. Fryer A.D. Eosinophil-associated inflammation in bronchial asthma: A connection to the nervous system Int Arch Allergy Immunol 107 1995 205-207
4. Van Schoor J. Joos G.F. Pauwels R.A. Indirect bronchial hyperresponsiveness in asthma: Mechanisms, pharmacology and implications for clinical research Eur Respir J 16 2000 514-533
5. D'Amato M. Vitiani L.R. Petrelli G. et al. Association of persistent bronchial hyperresponsiveness with beta2-adrenoceptor (ADRB2) haplotypes, A population study Am J Respir Crit Care Med 158 1998 1968-1973
6. Swystun V.A. Gordon J.R. Davis E.B. et al. Mast cell tryptase release and asthmatic responses to allergen increase with regular use of salbutamol J Allergy Clin Immunol 106 2000 57-64
7. Cloosterman S.G. Bijl-Hofland I.D. van Herwaarden C.L. et al. A Placebo-controlled clinical trial of regular monotherapy with short-acting and long-acting beta(2)-Agonists in allergic asthmatic patients Chest 119 2001 1306-1315
8. Wahedna I. Wong C.S. Wisniewski A.F.Z. et al. Asthma control during and after cessation of regular beta2-agonists treatment Am Rev Respir Dis 148 1993 707-712
9. Nelson H.S. Clinical experience with levalbuterol J Allergy Clin Immunol 104 1999 s77-s84
10. Handley D. The asthma-like pharmacology and toxicology of (S)-isomers of β agonists J Allergy Clin Immunol 104 1999 s69-s76
11. Sanjar S. Morley J. Airway hyperreactivity Lancet 2 1988 160-161
12. Sanjar S. Kristersson A. Mazzoni L. et al. Increased airway reactivity in the guinea-pig follows exposure to intravenous isoprenaline J Physiol 425 1990 43-54
13. Small K.M. McGraw D.W. Liggett S.B. Pharmacology and physiology of human adrenergic receptor polymorphisms Annu Rev Pharmacol Toxicol 43 2003 381-411
14. Israel E. Drazen J.M. Liggett S.B. et al. The effect of polymorphisms of the beta(2)-adrenergic receptor on the response to regular use of albuterol in asthma Am J Respir Crit Care Med 162 2000 75-80
15. NHLBI/WHO Workshop Report. Global strategy for asthma management and prevention: Global Initiative for Asthma (GINA), National Institute of Health, Public Nb, 95-3659, 1995.
16. Gumbhir-Shah K. Kellerman D.J. DeGraw S. et al. Pharmacokinetics and pharmacodynamics of cumulative single doses of inhaled salbutamol enantiomers in asthmatic subjects Pulm Pharmacol Ther 12 1999 353-362
17. Roca J. Burgos F. Sunyer J. et al. References values for forced spirometry. Group of the European Community Respiratory Health Survey Eur Respir J 11 1998 1354-1362
18. Peterson C.G.B. Enander I. Nystrand J. et al. Radioimmunoassay of human eosinophil cationic protein (ECP) by an improved method. Establishment of normal levels in serum and turnover in vivo Clin Exp Allergy 21 1990 561-567
19. Naidu Sjöswärd K. Josefsson M. Ahlner J. et al. Metabolism of salbutamol differs between asthmatics and healthy volunteers Pharmacol Toxicol 92 1 2003 27-32
20. Coughtrie M.W. Gilissen R.A. Shek B. et al. Phenol sulphotransferase SULT1A1 polymorphism: Molecular diagnosis and allele frequencies in Caucasian and African populations Biochem J 337 Pt 1 1999 45-49
21. Peng C.T. Chen J.C. Yeh K.T. et al. The relationship among the polymorphisms of SULT1A1, 1A2 and different types of cancers in Taiwanese Int J Mol Med 11 2003 85-89
22. Ronaghi M, Uhlen M, Nyren P. A sequencing method based on real-time pyrophosphate. Science 1998;281 363, 365.
23. Handley D.A. McCullough J.R. Crowther S.D. et al. Sympathomimetic enantiomers and asthma Chirality 10 1998 262-272
24. Pennings H.J. Wouters E.F. Effect of inhaled beclomethasone dipropionate on isocapnic hyperventilation with cold air in asthmatics, measured with forced oscillation technique Eur Respir J 10 1997 665-671
25. Boulton D.W. Fawcett J.P. The pharmacokinetics of levosalbutamol: what are the clinical implications? Clin Pharmacokinet 40 2001 23-40
26. Verleden G.M. Belvisi M.G. Rabe K.F. et al. Beta 2-adrenoceptor agonists inhibit NANC neural bronchoconstrictor responses in vitro J Appl Physiol 74 1993 1195-1199
27. Hall I.P. Wheatley A. Wilding P. et al. Association of Glu 27 β2-adrenoceptor polymorphism with lower airway reactivity in asthmatic subjects Lancet 345 1995 1213-1214
28. Liggett S.B. Molecular and genetic basis of β2-adrenergic receptor function J Allergy Clin Immunol 104 1999 s42-s46
29. Ulbrecht M. Hergeth M.T. Wjst M. et al. Association of beta(2)-adrenoreceptor variants with bronchial hyperresponsiveness Am J Respir Crit Care Med 161 2000 469-474
30. Chong L.K. Chowdry J. Ghahramani P. et al. Influence of genetic polymorphisms in the beta2-adrenoceptor on desensitization in human lung mast cells Pharmacogenetics 10 2000 153-162
31. Schmekel B. Smith H.J. The diagnostic capacity of forced oscillation and forced expiration techniques in identifying asthma by isocapnic hyperpnoea of cold air Eur Respir J 10 1997 2243-2249
32. Salome C.M. Thorpe C.W. Diba C. et al. Airway re-narrowing following deep inspiration in asthmatic and nonasthmatic subjects Eur Respir J 22 2003 62-68
33. Gayrard P. Orehek J. Grimaud C. et al. Bronchoconstrictor effect of a deep inspiration in patients with asthma Am Rev Respir Dis 111 1975 433-439
34. Goldman M.D. Clinical application of forced oscillation Pulm Pharmacol Ther 14 2001 341-350
35. Boulton D.W. Fawcett J.P. Pharmacokinetics and pharmacodynamics of single oral doses of albuterol and its enantiomers in humans Clin Pharmacol Ther 62 1997 138-144