Challenges in constructing statistically based structure-activity relationship models for developmental toxicity

Birth Defects Research Part A - Clinical and Molecular Teratology

Volumn 70, Issue 12, 2004, Pages 902-911

  Julien, Elizabeth ^a   Willhite, Calvin C ^b   Richard, Ann M ^c   DeSesso, John M ^d  

^a International Life Sciences Institute   (United States)

^b California Dept Toxic Subs Contr   (United States)

^c U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^d NOBLIS   (United States)

Author keywords

Developmental toxicity; Predictive models; Safety assessment; Screening; Structure activity relationship; Teratology

Indexed keywords

ANIMAL MODEL; CHEMICAL CARCINOGENESIS; CONFERENCE PAPER; ENVIRONMENTAL EXPOSURE; HEALTH HAZARD; HUMAN; MOUSE; NONHUMAN; PREDICTION; PRIORITY JOURNAL; RAT; SAFETY; SCREENING; SPECIES DIFFERENCE; STATISTICAL ANALYSIS; STATISTICAL MODEL; STRUCTURE ACTIVITY RELATION; TERATOLOGY; TOXICITY TESTING;

ABNORMALITIES; FETAL DEVELOPMENT; HUMANS; MODELS, STATISTICAL; RISK ASSESSMENT; STRUCTURE-ACTIVITY RELATIONSHIP; TERATOGENS;

EID: 11144263227     PISSN: 15420752     EISSN: None     Source Type: Journal    
DOI: 10.1002/bdra.20087     Document Type: Conference Paper

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