-
1
-
-
0024847290
-
What is synergy?
-
Erratum in Pharmacol Rev 41:422 (1990)
-
Berenbaum MC (1989) What is synergy? Pharmacol Rev 41:93-141 [Erratum in Pharmacol Rev 41:422 (1990)]
-
(1989)
Pharmacol Rev
, vol.41
, pp. 93-141
-
-
Berenbaum, M.C.1
-
2
-
-
0031883784
-
Carbamazepine toxicity with lamotrigine: Pharmacokinetic or pharmacodynamic interaction?
-
Besag FM, Berry DJ, Pool F, Newbery JE, Subel B (1998) Carbamazepine toxicity with lamotrigine: pharmacokinetic or pharmacodynamic interaction? Epilepsia 39:183-187
-
(1998)
Epilepsia
, vol.39
, pp. 183-187
-
-
Besag, F.M.1
Berry, D.J.2
Pool, F.3
Newbery, J.E.4
Subel, B.5
-
3
-
-
0036713855
-
Effect of gabapentin on the anticonvulsant activity of antiepileptic drugs against electroconvulsions in mice - An isobolographic analysis
-
Borowicz KK, Swiader M, Luszczki J, Czuczwar SJ (2002) Effect of gabapentin on the anticonvulsant activity of antiepileptic drugs against electroconvulsions in mice - an isobolographic analysis. Epilepsia 43:956-963
-
(2002)
Epilepsia
, vol.43
, pp. 956-963
-
-
Borowicz, K.K.1
Swiader, M.2
Luszczki, J.3
Czuczwar, S.J.4
-
4
-
-
0036178278
-
Ignoring pharmacokinetics may lead to isoboles misinterpretation: Illustration with the norfloxacin-theophylline convulsant interaction in rats
-
Cadart M, Marchand S, Pariat C, Bouquet S, Couet W (2002) Ignoring pharmacokinetics may lead to isoboles misinterpretation: illustration with the norfloxacin-theophylline convulsant interaction in rats. Pharm Res 19:209-214
-
(2002)
Pharm Res
, vol.19
, pp. 209-214
-
-
Cadart, M.1
Marchand, S.2
Pariat, C.3
Bouquet, S.4
Couet, W.5
-
5
-
-
0033014517
-
An in vitro electrophysiological study on the effects of phenytoin, lamotrigine and gabapentin on striatal neurons
-
Calabresi P, Centonze D, Marfia GA, Pisani A, Bernardi G (1999) An in vitro electrophysiological study on the effects of phenytoin, lamotrigine and gabapentin on striatal neurons. Br J Pharmacol 126:689-696
-
(1999)
Br J Pharmacol
, vol.126
, pp. 689-696
-
-
Calabresi, P.1
Centonze, D.2
Marfia, G.A.3
Pisani, A.4
Bernardi, G.5
-
6
-
-
0026443902
-
An in vitro investigation of the action of lamotrigine on neuronal voltage-activated sodium channels
-
Cheung H, Kamp D, Harris E (1992) An in vitro investigation of the action of lamotrigine on neuronal voltage-activated sodium channels. Epilepsy Res 13:107-112
-
(1992)
Epilepsy Res
, vol.13
, pp. 107-112
-
-
Cheung, H.1
Kamp, D.2
Harris, E.3
-
7
-
-
0033761218
-
Selection of antiepileptic drug polytherapy based on mechanisms of action: The evidence reviewed
-
Deckers CL, Czuczwar SJ, Hekster YA, Keyser A, Kubova H, Meinardi H, Patsalos PN, Renier WO, Van Rijn CM (2000) Selection of antiepileptic drug polytherapy based on mechanisms of action: the evidence reviewed. Epilepsia 41:1364-1374
-
(2000)
Epilepsia
, vol.41
, pp. 1364-1374
-
-
Deckers, C.L.1
Czuczwar, S.J.2
Hekster, Y.A.3
Keyser, A.4
Kubova, H.5
Meinardi, H.6
Patsalos, P.N.7
Renier, W.O.8
Van Rijn, C.M.9
-
8
-
-
0024449997
-
Animal models of the epilepsies
-
Fischer RS (1989) Animal models of the epilepsies. Brain Res Rev 14:245-278
-
(1989)
Brain Res Rev
, vol.14
, pp. 245-278
-
-
Fischer, R.S.1
-
9
-
-
0032797436
-
Preclinical evaluation of newly approved and potential antiepileptic drugs against cocaine-induced seizures
-
Gasior M, Ungard JT, Witkin JM (1999) Preclinical evaluation of newly approved and potential antiepileptic drugs against cocaine-induced seizures. J Pharmacol Exp Ther 290:1148-1156
-
(1999)
J Pharmacol Exp Ther
, vol.290
, pp. 1148-1156
-
-
Gasior, M.1
Ungard, J.T.2
Witkin, J.M.3
-
10
-
-
0026520451
-
Topical reviews: A new type of report in pain
-
Gebhart GF (1992) Topical reviews: a new type of report in pain. Pain 49:1
-
(1992)
Pain
, vol.49
, pp. 1
-
-
Gebhart, G.F.1
-
11
-
-
0029563665
-
Isobolographic analysis of interactions: An update on applications and utility
-
Gessner PK (1995) Isobolographic analysis of interactions: an update on applications and utility. Toxicology 105:161-179
-
(1995)
Toxicology
, vol.105
, pp. 161-179
-
-
Gessner, P.K.1
-
13
-
-
0029036955
-
The search for synergy: A critical review from response surface perspective
-
Greco WR, Bravo G, Parsons JC (1995) The search for synergy: a critical review from response surface perspective. Pharmacol Rev 47:331-385
-
(1995)
Pharmacol Rev
, vol.47
, pp. 331-385
-
-
Greco, W.R.1
Bravo, G.2
Parsons, J.C.3
-
14
-
-
0002674011
-
Benzodiazepines. Mechanisms of action
-
Levy R, Mattson R, Meldrum B, Penry JK, Dreifuss FE (eds) Raven, New York
-
Haefely W (1989) Benzodiazepines. Mechanisms of action. In: Levy R, Mattson R, Meldrum B, Penry JK, Dreifuss FE (eds) Antiepileptic drugs, 3rd edn. Raven, New York, pp 721-734
-
(1989)
Antiepileptic Drugs, 3rd Edn.
, pp. 721-734
-
-
Haefely, W.1
-
15
-
-
0033758726
-
Open study evaluating lamotrigine efficacy and safety in add-on treatment and consecutive monotherapy in patients with carbamazepine- or valproate-resistant epilepsy
-
Jozwiak S, Terczynski A (2000) Open study evaluating lamotrigine efficacy and safety in add-on treatment and consecutive monotherapy in patients with carbamazepine- or valproate-resistant epilepsy. Seizure 9:486-492
-
(2000)
Seizure
, vol.9
, pp. 486-492
-
-
Jozwiak, S.1
Terczynski, A.2
-
16
-
-
0030919715
-
Evaluation of synergism by a novel three-dimensional model for the combined action of cisplatin and etoposide on the growth of a human small-cell lung-cancer cell line, SBC-3
-
Kanzawa F, Nishio K, Fukuoka K, Fukuda M, Kunimoto T, Saijo N (1997) Evaluation of synergism by a novel three-dimensional model for the combined action of cisplatin and etoposide on the growth of a human small-cell lung-cancer cell line, SBC-3. Int J Cancer 71:311-319
-
(1997)
Int J Cancer
, vol.71
, pp. 311-319
-
-
Kanzawa, F.1
Nishio, K.2
Fukuoka, K.3
Fukuda, M.4
Kunimoto, T.5
Saijo, N.6
-
17
-
-
0026304850
-
Neurochemical and behavioral aspects of lamotrigine
-
Leach MJ, Baxter MG, Critchley MA (1991) Neurochemical and behavioral aspects of lamotrigine. Epilepsia 32 (Suppl 2):S4-S8
-
(1991)
Epilepsia
, vol.32
, Issue.2 SUPPL.
-
-
Leach, M.J.1
Baxter, M.G.2
Critchley, M.A.3
-
18
-
-
84951384024
-
A simplified method of evaluating dose-effect experiments
-
Litchfield JT, Wilcoxon F (1949) A simplified method of evaluating dose-effect experiments. J Pharmacol Exp Ther 96:99-113
-
(1949)
J Pharmacol Exp Ther
, vol.96
, pp. 99-113
-
-
Litchfield, J.T.1
Wilcoxon, F.2
-
19
-
-
0001663843
-
The problem of synergism and antagonism of combined drugs
-
Loewe S (1953) The problem of synergism and antagonism of combined drugs. Arzneimittelforschung 3:285-290
-
(1953)
Arzneimittelforschung
, vol.3
, pp. 285-290
-
-
Loewe, S.1
-
20
-
-
0023897574
-
Which animal models should be used in the search for new antiepileptic drugs? A proposal based on experimental and clinical considerations
-
Löscher W, Schmidt D (1988) Which animal models should be used in the search for new antiepileptic drugs? A proposal based on experimental and clinical considerations. Epilepsy Res 2:145-181
-
(1988)
Epilepsy Res
, vol.2
, pp. 145-181
-
-
Löscher, W.1
Schmidt, D.2
-
21
-
-
0025982093
-
The role of technical, biological and pharmacological factors in the laboratory evaluation of anticonvulsant drugs. II. Maximal electroshock seizure models
-
Löscher W, Fassbender CP, Nolting B (1991) The role of technical, biological and pharmacological factors in the laboratory evaluation of anticonvulsant drugs. II. Maximal electroshock seizure models. Epilepsy Res 8:79-94
-
(1991)
Epilepsy Res
, vol.8
, pp. 79-94
-
-
Löscher, W.1
Fassbender, C.P.2
Nolting, B.3
-
22
-
-
0141643366
-
Isobolographic and subthreshold methods in the detection of interactions between oxcarbazepine and conventional antiepileptics-a comparative study
-
Luszczki JJ, Czuczwar SJ (2003) Isobolographic and subthreshold methods in the detection of interactions between oxcarbazepine and conventional antiepileptics-a comparative study. Epilepsy Res 56:27-42
-
(2003)
Epilepsy Res
, vol.56
, pp. 27-42
-
-
Luszczki, J.J.1
Czuczwar, S.J.2
-
23
-
-
2142660737
-
Isobolographic profile of interactions between tiagabine and gabapentin: A preclinical study
-
Luszczki JJ, Czuczwar SJ (2004) Isobolographic profile of interactions between tiagabine and gabapentin: a preclinical study. Naunyn-Schmiedeberg's Arch Pharmacol 369:434-446
-
(2004)
Naunyn-Schmiedeberg's Arch Pharmacol
, vol.369
, pp. 434-446
-
-
Luszczki, J.J.1
Czuczwar, S.J.2
-
24
-
-
0042572368
-
Interactions of lamotrigine with topiramate and first-generation antiepileptic drugs in the maximal electroshock test in mice: An isobolographic analysis
-
Luszczki JJ, Czuczwar M, Kis J, Krysa J, Pasztelan I, Swiader M, Czuczwar SJ (2003a) Interactions of lamotrigine with topiramate and first-generation antiepileptic drugs in the maximal electroshock test in mice: an isobolographic analysis. Epilepsia 44:1003-1013
-
(2003)
Epilepsia
, vol.44
, pp. 1003-1013
-
-
Luszczki, J.J.1
Czuczwar, M.2
Kis, J.3
Krysa, J.4
Pasztelan, I.5
Swiader, M.6
Czuczwar, S.J.7
-
25
-
-
0038045883
-
Interactions between oxcarbazepine and conventional antiepileptic drugs in the maximal electroshock test in mice: An isobolographic analysis
-
Luszczki JJ, Borowicz KK, Swiader M, Czuczwar SJ (2003b) Interactions between oxcarbazepine and conventional antiepileptic drugs in the maximal electroshock test in mice: an isobolographic analysis. Epilepsia 44:489-499
-
(2003)
Epilepsia
, vol.44
, pp. 489-499
-
-
Luszczki, J.J.1
Borowicz, K.K.2
Swiader, M.3
Czuczwar, S.J.4
-
26
-
-
0038107702
-
Interactions of tiagabine with some antiepileptics in the maximal electroshock in mice
-
Luszczki JJ, Swiader M, Czuczwar M, Kis J, Czuczwar SJ (2003c) Interactions of tiagabine with some antiepileptics in the maximal electroshock in mice. Pharmacol Biochem Behav 75:319-327
-
(2003)
Pharmacol Biochem Behav
, vol.75
, pp. 319-327
-
-
Luszczki, J.J.1
Swiader, M.2
Czuczwar, M.3
Kis, J.4
Czuczwar, S.J.5
-
27
-
-
1642377949
-
Benzodiazepine. Mechanisms of action
-
Levy RH, Mattson RH, Meldrum BS, Perucca E (eds) Lippincott, Philadelphia
-
Macdonald RL (2002) Benzodiazepine. Mechanisms of action. In: Levy RH, Mattson RH, Meldrum BS, Perucca E (eds) Antiepileptic drugs, 5th edn. Lippincott, Philadelphia, pp 179-186
-
(2002)
Antiepileptic Drugs, 5th Edn.
, pp. 179-186
-
-
Macdonald, R.L.1
-
28
-
-
0023832339
-
Benzodiazepines, but not beta carbolines, limit high frequency repetitive firing of action potentials of spinal cord neurons in cell culture
-
McLean MJ, Macdonald RL (1988) Benzodiazepines, but not beta carbolines, limit high frequency repetitive firing of action potentials of spinal cord neurons in cell culture. J Pharmacol Exp Ther 244:789-795
-
(1988)
J Pharmacol Exp Ther
, vol.244
, pp. 789-795
-
-
McLean, M.J.1
Macdonald, R.L.2
-
30
-
-
0025216638
-
Modulation of morphine antinociception by peripheral [Leu5]enkephalin: A synergistic interaction
-
Porreca F, Jiang Q, Tallarida RJ (1990) Modulation of morphine antinociception by peripheral [Leu5]enkephalin: a synergistic interaction. Eur J Pharmacol 179:463-468
-
(1990)
Eur J Pharmacol
, vol.179
, pp. 463-468
-
-
Porreca, F.1
Jiang, Q.2
Tallarida, R.J.3
-
31
-
-
0025756141
-
Three-dimensional analysis of the synergistic cytotoxicity of gancyclovir and zidovudine
-
Prichard MN, Prichard LE, Baguley WA, Nassiri MR, Shipman C (1991) Three-dimensional analysis of the synergistic cytotoxicity of gancyclovir and zidovudine. Antimicrob Agents Chemother 35:1060-1065
-
(1991)
Antimicrob Agents Chemother
, vol.35
, pp. 1060-1065
-
-
Prichard, M.N.1
Prichard, L.E.2
Baguley, W.A.3
Nassiri, M.R.4
Shipman, C.5
-
32
-
-
0027416573
-
Strategic design and tree-dimensional analysis of antiviral drug combinations
-
Prichard MN, Prichard LE, Shipman C (1993) Strategic design and tree-dimensional analysis of antiviral drug combinations. Antimicrob Agents Chemother 37:540-545
-
(1993)
Antimicrob Agents Chemother
, vol.37
, pp. 540-545
-
-
Prichard, M.N.1
Prichard, L.E.2
Shipman, C.3
-
33
-
-
0036747357
-
Seizure freedom with more than one antiepileptic drug
-
Stephen LJ, Brodie MJ (2002) Seizure freedom with more than one antiepileptic drug. Seizure 11:349-351
-
(2002)
Seizure
, vol.11
, pp. 349-351
-
-
Stephen, L.J.1
Brodie, M.J.2
-
34
-
-
0026774681
-
Zero interaction response surfaces, interaction functions and difference response surfaces for combinations of biologically active agents
-
Sühnel J (1992) Zero interaction response surfaces, interaction functions and difference response surfaces for combinations of biologically active agents. Arzneimittelforschung 42:1251-1258
-
(1992)
Arzneimittelforschung
, vol.42
, pp. 1251-1258
-
-
Sühnel, J.1
-
35
-
-
0032030117
-
Parallel dose-response curves in combination experiments
-
Sühnel J (1998) Parallel dose-response curves in combination experiments. Bull Math Biol 60:197-213
-
(1998)
Bull Math Biol
, vol.60
, pp. 197-213
-
-
Sühnel, J.1
-
36
-
-
0026589474
-
Statistical analysis of drug combinations for synergism
-
Tallarida RJ (1992) Statistical analysis of drug combinations for synergism. Pain 49:93-97
-
(1992)
Pain
, vol.49
, pp. 93-97
-
-
Tallarida, R.J.1
-
38
-
-
0034889197
-
Drug synergism: Its detection and applications
-
Tallarida RJ (2001) Drug synergism: its detection and applications. J Pharmcol Exp Ther 298:865-872
-
(2001)
J Pharmcol Exp Ther
, vol.298
, pp. 865-872
-
-
Tallarida, R.J.1
-
39
-
-
0036299135
-
The interaction index: A measure of drug synergism
-
Tallarida RJ (2002) The interaction index: a measure of drug synergism. Pain 98:163-168
-
(2002)
Pain
, vol.98
, pp. 163-168
-
-
Tallarida, R.J.1
-
41
-
-
0030454477
-
Inhibition of N-type calcium currents by lamotrigine in rat amygdala neurones
-
Wang SJ, Huang CC, Hsu KS, Tsai JJ, Gean PW (1996) Inhibition of N-type calcium currents by lamotrigine in rat amygdala neurones. Neuroreport 7:3037-3040
-
(1996)
Neuroreport
, vol.7
, pp. 3037-3040
-
-
Wang, S.J.1
Huang, C.C.2
Hsu, K.S.3
Tsai, J.J.4
Gean, P.W.5
-
43
-
-
0010009818
-
Discovery and preclinical development of antiepileptic drugs
-
Levy RH, Mattson RH, Meldrum BS, Perucca E (eds) Lippincott, Philadelphia
-
White HS, Woodhead JH, Wilcox KS, Stables JP, Kupferberg HJ, Wolf HH (2002) Discovery and preclinical development of antiepileptic drugs. In: Levy RH, Mattson RH, Meldrum BS, Perucca E (eds) Antiepileptic drugs, 5th edn. Lippincott, Philadelphia, pp 36-48
-
(2002)
Antiepileptic Drugs, 5th Edn.
, pp. 36-48
-
-
White, H.S.1
Woodhead, J.H.2
Wilcox, K.S.3
Stables, J.P.4
Kupferberg, H.J.5
Wolf, H.H.6
|