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Volumn 126, Issue 3, 1999, Pages 689-696

An in vitro electrophysiological study on the effects of phenytoin, lamotrigine and gabapentin on striatal neurons

Author keywords

Antiepileptic drugs; Epilepsy; Excitatory amino acids; Intracellular recordings; Striatum; Synaptic transmission

Indexed keywords

ANTICONVULSIVE AGENT; GABAPENTIN; LAMOTRIGINE; PHENYTOIN;

EID: 0033014517     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0702361     Document Type: Article
Times cited : (67)

References (53)
  • 1
    • 0019898532 scopus 로고
    • Relationship between the striatal system and amygdaloid paroxysmal activity
    • AMATO, G., CRESCIMANNO, G., SORBERA, F. & LA GRUTTA, V. (1982). Relationship between the striatal system and amygdaloid paroxysmal activity. Exp. Neurol., 77, 492-504.
    • (1982) Exp. Neurol. , vol.77 , pp. 492-504
    • Amato, G.1    Crescimanno, G.2    Sorbera, F.3    La Grutta, V.4
  • 2
    • 4244138850 scopus 로고
    • Gabapentin and convulsions provoked by excitatory amino acids
    • BARTOSZYK, G.D. (1982). Gabapentin and convulsions provoked by excitatory amino acids. Naunyn Schmiedebergs Arch. Pharmacol., 324, R24.
    • (1982) Naunyn Schmiedebergs Arch. Pharmacol. , vol.324
    • Bartoszyk, G.D.1
  • 3
    • 0026334826 scopus 로고
    • Riluzole specifically blocks inactivated Na channels in myelinated nerve fibre
    • BENOIT, E. & ESCANDE, D. (1991). Riluzole specifically blocks inactivated Na channels in myelinated nerve fibre. Pflügers Arch., 419, 603-609.
    • (1991) Pflügers Arch. , vol.419 , pp. 603-609
    • Benoit, E.1    Escande, D.2
  • 4
    • 0030958871 scopus 로고    scopus 로고
    • Endogenous adenosine mediates the presynaptic inhibition induced by aglycemia at corticostriatal synapses
    • CALABRESI, P., CENTONZE, D., PISANI, A. & BERNARDI, G. (1997a). Endogenous adenosine mediates the presynaptic inhibition induced by aglycemia at corticostriatal synapses. J. Neurosci., 17, 4509-4516.
    • (1997) J. Neurosci. , vol.17 , pp. 4509-4516
    • Calabresi, P.1    Centonze, D.2    Pisani, A.3    Bernardi, G.4
  • 5
    • 0031978837 scopus 로고    scopus 로고
    • Striatal spiny neurons and cholinergic interneurons express differential ionotropic glutamatergic responses and vulnerability: Implications for ischemia and Huntington's disease
    • CALABRESI, P., CENTONZE, D., PISANI, A., SANCESARIO, G., GUBELLINI, P., MARFIA, G.A. & BERNARDI G. (1998). Striatal spiny neurons and cholinergic interneurons express differential ionotropic glutamatergic responses and vulnerability: implications for ischemia and Huntington's disease. Ann. Neurol., 43, 586-597.
    • (1998) Ann. Neurol. , vol.43 , pp. 586-597
    • Calabresi, P.1    Centonze, D.2    Pisani, A.3    Sancesario, G.4    Gubellini, P.5    Marfia, G.A.6    Bernardi, G.7
  • 7
    • 0029122730 scopus 로고
    • Action of GP47779, the active metabolite of oxcarbazepine, on corticostriatal system. I. Modulation of corticostriatal synaptic transmission
    • CALABRESI, P., DE MURTAS, M., STEFANI, A., PISANI, A., SANCESARIO, G., MERCURI, N.B. & BERNARDI, G. (1995b). Action of GP47779, the active metabolite of oxcarbazepine, on corticostriatal system. I. Modulation of corticostriatal synaptic transmission. Epilepsia, 36, 990-996.
    • (1995) Epilepsia , vol.36 , pp. 990-996
    • Calabresi, P.1    De Murtas, M.2    Stefani, A.3    Pisani, A.4    Sancesario, G.5    Mercuri, N.B.6    Bernardi, G.7
  • 8
    • 0343554027 scopus 로고    scopus 로고
    • Opposite membrane potential changes induced by glucose deprivation in striatal spiny neurons and in large aspiny interneurons
    • CALABRESI, P., MAGARINOS ASCONE, C., CENTONZE, D., PISANI, A., SANCESARIO, G., D'ANGELO, V. & BERNARDI, G. (1997b). Opposite membrane potential changes induced by glucose deprivation in striatal spiny neurons and in large aspiny interneurons. J. Neurosci., 17, 1940-1949.
    • (1997) J. Neurosci. , vol.17 , pp. 1940-1949
    • Calabresi, P.1    Magarinos Ascone, C.2    Centonze, D.3    Pisani, A.4    Sancesario, G.5    D'Angelo, V.6    Bernardi, G.7
  • 9
    • 0026526276 scopus 로고
    • Long-term synaptic depression in the striatum: Physiological and pharmacological characterization
    • CALABRESI, P., MAJ, R., PISANI, A., MERCURI, N.B. & BERNARDI, G. (1992a). Long-term synaptic depression in the striatum: physiological and pharmacological characterization. J. Neurosci., 12, 4224-4233.
    • (1992) J. Neurosci. , vol.12 , pp. 4224-4233
    • Calabresi, P.1    Maj, R.2    Pisani, A.3    Mercuri, N.B.4    Bernardi, G.5
  • 10
    • 0025266679 scopus 로고
    • Synaptic and intrinsic control of membrane excitability of neostriatal neurons. II. An in vitro analysis
    • CALABRESI, P., MERCURI, N.B. & BERNARDI, G. (1990a). Synaptic and intrinsic control of membrane excitability of neostriatal neurons. II. An in vitro analysis. J. Neurophysiol., 63, 663-675.
    • (1990) J. Neurophysiol. , vol.63 , pp. 663-675
    • Calabresi, P.1    Mercuri, N.B.2    Bernardi, G.3
  • 11
    • 0025274408 scopus 로고
    • Synaptic and intrinsic control of membrane excitability of neostriatal neurons. I. An in vivo analysis
    • CALABRESI, P., MERCURI, N.B. & BERNARDI, G. (1990b). Synaptic and intrinsic control of membrane excitability of neostriatal neurons. I. An in vivo analysis. J. Neurophysiol., 63, 651-662.
    • (1990) J. Neurophysiol. , vol.63 , pp. 651-662
    • Calabresi, P.1    Mercuri, N.B.2    Bernardi, G.3
  • 12
    • 0026674199 scopus 로고
    • Long-term potentiation in the striatum is unmasked by removing the voltage-dependent blockade of NMDA receptor channel
    • CALABRESI, P., PISANI, A., MERCURI, N.B. & BERNARDI, G. (1992b). Long-term potentiation in the striatum is unmasked by removing the voltage-dependent blockade of NMDA receptor channel. Eur. J. Neurosci., 4, 929-935.
    • (1992) Eur. J. Neurosci. , vol.4 , pp. 929-935
    • Calabresi, P.1    Pisani, A.2    Mercuri, N.B.3    Bernardi, G.4
  • 13
    • 0030064639 scopus 로고    scopus 로고
    • The corticostriatal projection: From synaptic plasticity to dysfunctions of the basal ganglia
    • CALABRESI, P., PISANI, A., MERCURI, N.B. & BERNARDI, G. (1996a). The corticostriatal projection: from synaptic plasticity to dysfunctions of the basal ganglia. Trends Neurosci., 19, 19-24.
    • (1996) Trends Neurosci. , vol.19 , pp. 19-24
    • Calabresi, P.1    Pisani, A.2    Mercuri, N.B.3    Bernardi, G.4
  • 14
    • 0029812585 scopus 로고    scopus 로고
    • A field potential analysis on the effects of lamotrigine, GP 47779, and felbamate in neocortical slices
    • CALABRESI, P., SINISCALCHI, A., PISANI, A., STEFANI, A., MERCURI, N.B. & BERNARDI, G. (1996b). A field potential analysis on the effects of lamotrigine, GP 47779, and felbamate in neocortical slices. Neurology, 47, 557-562.
    • (1996) Neurology , vol.47 , pp. 557-562
    • Calabresi, P.1    Siniscalchi, A.2    Pisani, A.3    Stefani, A.4    Mercuri, N.B.5    Bernardi, G.6
  • 15
    • 0028293957 scopus 로고
    • Neurophysiological, pharmacological and morphological properties of human caudate neurons recorded in vitro
    • CEPEDA, C., WALSH, J.P., PEACOCK, W., BUCKWALD, N.A. & LEVINE, M.S. (1994). Neurophysiological, pharmacological and morphological properties of human caudate neurons recorded in vitro. Neuroscience, 59, 89-103.
    • (1994) Neuroscience , vol.59 , pp. 89-103
    • Cepeda, C.1    Walsh, J.P.2    Peacock, W.3    Buckwald, N.A.4    Levine, M.S.5
  • 16
    • 0026443902 scopus 로고
    • An in vitro investigation of the action of lamotrigine on neuronal-activated sodium channels
    • CHEUNG, H., KAMP, D. & HARRIS, E. (1992). An in vitro investigation of the action of lamotrigine on neuronal-activated sodium channels. Epilepsy Res., 13, 107-112.
    • (1992) Epilepsy Res. , vol.13 , pp. 107-112
    • Cheung, H.1    Kamp, D.2    Harris, E.3
  • 17
    • 0017339785 scopus 로고
    • High affinity uptake of glutamate in terminals of corticostriatal axons
    • DIVAC, I., FONNUM, F. & STORM-MATHISON, J. (1977). High affinity uptake of glutamate in terminals of corticostriatal axons. Nature, 266, 377-378.
    • (1977) Nature , vol.266 , pp. 377-378
    • Divac, I.1    Fonnum, F.2    Storm-Mathison, J.3
  • 18
    • 0017897901 scopus 로고
    • Anatomical correlates of electrical and behavioral events related to amygdala kindling
    • ENGEL, J., WOLFSON, L. & BROWN, L. (1978). Anatomical correlates of electrical and behavioral events related to amygdala kindling. Ann. Neurol., 3, 538-544.
    • (1978) Ann. Neurol. , vol.3 , pp. 538-544
    • Engel, J.1    Wolfson, L.2    Brown, L.3
  • 19
    • 0002394966 scopus 로고
    • The propagation of cortical and sub-cortical epileptic discharge
    • FAETH, W.H., WALKER, A.E. & ANDY, O.J. (1954). The propagation of cortical and sub-cortical epileptic discharge. Epilepsia, 3, 37-48.
    • (1954) Epilepsia , vol.3 , pp. 37-48
    • Faeth, W.H.1    Walker, A.E.2    Andy, O.J.3
  • 20
    • 0026524643 scopus 로고
    • Subcortical structures and pathways involved in convulsive seizure generation
    • GALE, K. (1992). Subcortical structures and pathways involved in convulsive seizure generation. J. Clin. Neurophysiol., 9, 264-277.
    • (1992) J. Clin. Neurophysiol. , vol.9 , pp. 264-277
    • Gale, K.1
  • 21
    • 0028365784 scopus 로고
    • New antiepileptic drugs
    • HARDEN, C.L. (1994). New antiepileptic drugs. Neurology, 44, 787-795.
    • (1994) Neurology , vol.44 , pp. 787-795
    • Harden, C.L.1
  • 22
    • 0023765726 scopus 로고
    • A versatile means of intracellular labelling: Injection of biocytin and its detection with avidin conjugates
    • HORIKAWA, H. & ARMSTRONG, W.E. (1988). A versatile means of intracellular labelling: injection of biocytin and its detection with avidin conjugates. J. Neurosci. Methods, 25, 1-11.
    • (1988) J. Neurosci. Methods , vol.25 , pp. 1-11
    • Horikawa, H.1    Armstrong, W.E.2
  • 23
    • 0026079995 scopus 로고
    • Membrane properties and synaptic responses of rat striatal neurones in vitro
    • JIANG, Z.-C. & NORTH, R.A. (1991). Membrane properties and synaptic responses of rat striatal neurones in vitro. J. Physiol., 443, 533-553.
    • (1991) J. Physiol. , vol.443 , pp. 533-553
    • Jiang, Z.-C.1    North, R.A.2
  • 24
    • 0021237226 scopus 로고
    • Passive electrical membrane properties of rat neostriatal neurons in an in vitro slice preparation
    • KITA, T., KITA, H. & KITAI, S.T. (1984). Passive electrical membrane properties of rat neostriatal neurons in an in vitro slice preparation. Brain Res., 300, 129-139.
    • (1984) Brain Res. , vol.300 , pp. 129-139
    • Kita, T.1    Kita, H.2    Kitai, S.T.3
  • 26
    • 0028258554 scopus 로고
    • + channels must deactivate to recover from inactivation
    • + channels must deactivate to recover from inactivation. Neuron, 12, 819-829.
    • (1994) Neuron , vol.12 , pp. 819-829
    • Kuo, C.-C.1    Bean, B.P.2
  • 27
    • 0022900644 scopus 로고
    • Pharmacological studies on lamotrigine, a novel potential antiepileptic drug: II Neurochemical studies on the mechanism of action
    • LEACH, M.J., MARDEN, C.M. & MILLER, A.A. (1986). Pharmacological studies on lamotrigine, a novel potential antiepileptic drug: II Neurochemical studies on the mechanism of action. Epilepsia, 27, 490-497.
    • (1986) Epilepsia , vol.27 , pp. 490-497
    • Leach, M.J.1    Marden, C.M.2    Miller, A.A.3
  • 28
    • 0028940581 scopus 로고
    • Sodium channel blockers reduce oxygen-glucose deprivation-induced cortical neuronal injury when combined with glutamate receptor antagonists
    • LYNCH III, J.J., YU, S.P., CANZONIERO, L.M.T., SENSI, S.L. & CHOI, D.W. (1995). Sodium channel blockers reduce oxygen-glucose deprivation-induced cortical neuronal injury when combined with glutamate receptor antagonists. J. Pharmacol. Exp. Ther., 273, 554-560.
    • (1995) J. Pharmacol. Exp. Ther. , vol.273 , pp. 554-560
    • Lynch J.J. III1    Yu, S.P.2    Canzoniero, L.M.T.3    Sensi, S.L.4    Choi, D.W.5
  • 30
    • 0002439117 scopus 로고    scopus 로고
    • Cellular effects of antiepileptic drugs
    • eds. Engel, J., & Pedley, T.A. Philadelphia: Lippincott-Raven Publishers
    • MACDONALD, R.L. (1996). Cellular effects of antiepileptic drugs. In Epilepsy: a comprehensive textbook. eds. Engel, J., & Pedley, T.A. pp. 1383-1391. Philadelphia: Lippincott-Raven Publishers.
    • (1996) Epilepsy: A Comprehensive Textbook , pp. 1383-1391
    • MacDonald, R.L.1
  • 31
    • 0002172544 scopus 로고    scopus 로고
    • Drugs effective in the therapy of the epilepsies
    • eds. Hardman, J.G. & Limbird, L.E. New York: McGraw-Hill
    • MCNAMARA, J.O. (1996). Drugs effective in the therapy of the epilepsies. In Goodman & Gilman's; The pharmacological basis of therapeutics. eds. Hardman, J.G. & Limbird, L.E. pp. 461-486. New York: McGraw-Hill.
    • (1996) Goodman & Gilman's; The Pharmacological Basis of Therapeutics , pp. 461-486
    • McNamara, J.O.1
  • 32
    • 0027368451 scopus 로고
    • Modulation of synaptic transmission and long-term potentiation: Effects on paired pulse facilitation and EPSC variance in the CA1 region of the hippocampus
    • MANABE, T., WYLLIE, D.J.I. & NICOLL, R.A. (1993). Modulation of synaptic transmission and long-term potentiation: effects on paired pulse facilitation and EPSC variance in the CA1 region of the hippocampus. J. Neurophysiol., 70, 1451-1459.
    • (1993) J. Neurophysiol. , vol.70 , pp. 1451-1459
    • Manabe, T.1    Wyllie, D.J.I.2    Nicoll, R.A.3
  • 33
    • 0028456066 scopus 로고
    • Clinical pharmacokinetics of gabapentin
    • MCLEAN, M.J. (1994). Clinical pharmacokinetics of gabapentin. Neurology, 44 (suppl 5): S17-S22.
    • (1994) Neurology , vol.44 , Issue.SUPPL. 5
    • McLean, M.J.1
  • 34
    • 0022516644 scopus 로고
    • Carbamazepine and 10,11-epoxycarbamazepine produce use- and voltage-dependent limitation of rapidly firing action potentials of mouse central neurons in cell culture
    • MCLEAN, M.J. & MACDONALD, R.L. (1986). Carbamazepine and 10,11-epoxycarbamazepine produce use- and voltage-dependent limitation of rapidly firing action potentials of mouse central neurons in cell culture. J. Pharmacol. Exp. Ther., 238, 727-737.
    • (1986) J. Pharmacol. Exp. Ther. , vol.238 , pp. 727-737
    • McLean, M.J.1    MacDonald, R.L.2
  • 35
    • 0021048081 scopus 로고
    • Multiple actions of phenytoin on mouse spinal cord neurons in cell culture
    • MCLEAN, M.J. & MACDONALD, R.L. (1983). Multiple actions of phenytoin on mouse spinal cord neurons in cell culture. J. Pharmacol. Exp. Ther., 227, 779-789.
    • (1983) J. Pharmacol. Exp. Ther. , vol.227 , pp. 779-789
    • McLean, M.J.1    MacDonald, R.L.2
  • 36
    • 0028535070 scopus 로고
    • The role of glutamate in epilepsy and other CNS disorders
    • MELDRUM, B.S. (1994). The role of glutamate in epilepsy and other CNS disorders. Neurology, 44 (suppl 8): S14-S23.
    • (1994) Neurology , vol.44 , Issue.SUPPL. 8
    • Meldrum, B.S.1
  • 37
    • 0001347460 scopus 로고
    • The anticonvulsant action of gabapentin involves the glycine/NMDA receptor
    • OLES, R.J., SINGH, L., HUGHES, J. & WOODRUFF, G.N. (1990). The anticonvulsant action of gabapentin involves the glycine/NMDA receptor. Soc. Neurosci., 16, 783.
    • (1990) Soc. Neurosci. , vol.16 , pp. 783
    • Oles, R.J.1    Singh, L.2    Hughes, J.3    Woodruff, G.N.4
  • 38
    • 0031048102 scopus 로고    scopus 로고
    • Gabapentin for parkinsonism: A double-blind, placebo-controlled, crossover trial
    • OLSON, W.L., GRUENTHAL, M., MUELLER, M.E. & OLSON, W.H. (1997). Gabapentin for parkinsonism: a double-blind, placebo-controlled, crossover trial. Am. J. Med., 102, 60-66.
    • (1997) Am. J. Med. , vol.102 , pp. 60-66
    • Olson, W.L.1    Gruenthal, M.2    Mueller, M.E.3    Olson, W.H.4
  • 40
    • 0027527142 scopus 로고
    • Gabapentin actions on ligand- and voltage-gated responses in cultured rodent neurons
    • ROCK, D.M., KELLY, K.M. & MACDONALD, R.L. (1993). Gabapentin actions on ligand- and voltage-gated responses in cultured rodent neurons. Epilepsy Res., 16, 89-98.
    • (1993) Epilepsy Res. , vol.16 , pp. 89-98
    • Rock, D.M.1    Kelly, K.M.2    MacDonald, R.L.3
  • 41
    • 0028136862 scopus 로고
    • Changes in paired-pulse facilitation suggest presynaptic involvement in long-term potentiation
    • SCHULZ, P.E., COOK, E.P. & JOHNSTON, D. (1994). Changes in paired-pulse facilitation suggest presynaptic involvement in long-term potentiation. J. Neurosci., 14, 5325-5337.
    • (1994) J. Neurosci. , vol.14 , pp. 5325-5337
    • Schulz, P.E.1    Cook, E.P.2    Johnston, D.3
  • 42
    • 0030911967 scopus 로고    scopus 로고
    • Lamotrigine trial in idiopathic parkinsonism: A double-blind, placebo-controlled, crossover study
    • SHINOTOH, H., VINGERHOETS, F.J., LEE, C.S., UITTI, R.J., SCHULZER, M., CALNE, D.B. & TSU, J. (1997). Lamotrigine trial in idiopathic parkinsonism: a double-blind, placebo-controlled, crossover study. Neurology, 48, 1282-1285.
    • (1997) Neurology , vol.48 , pp. 1282-1285
    • Shinotoh, H.1    Vingerhoets, F.J.2    Lee, C.S.3    Uitti, R.J.4    Schulzer, M.5    Calne, D.B.6    Tsu, J.7
  • 43
    • 0031036733 scopus 로고    scopus 로고
    • Effects of riluzole on rat cortical neurones: An in vitro electrophysiological study
    • SINISCALCHI, A., BONCI, A., MERCURI, N.B. & BERNARDI, G. (1997). Effects of riluzole on rat cortical neurones: an in vitro electrophysiological study. Br. J. Pharmacol., 120, 225-230.
    • (1997) Br. J. Pharmacol. , vol.120 , pp. 225-230
    • Siniscalchi, A.1    Bonci, A.2    Mercuri, N.B.3    Bernardi, G.4
  • 44
    • 0030984765 scopus 로고    scopus 로고
    • Stimulation of basal and L-DOPA-induced motor activity by glutamate antagonists in animal models of Parkinson's disease
    • STARR, M.S., STARR, B.J. & KAUR, J. (1997). Stimulation of basal and L-DOPA-induced motor activity by glutamate antagonists in animal models of Parkinson's disease. Neurosci. Biobehav. Rev., 21, 437-446.
    • (1997) Neurosci. Biobehav. Rev. , vol.21 , pp. 437-446
    • Starr, M.S.1    Starr, B.J.2    Kaur, J.3
  • 45
    • 0031239776 scopus 로고    scopus 로고
    • Differential inhibition by riluzole, lamotrigine and phenytoin of sodium and calcium currents in cortical neurons: Implication for neuroprotective strategies
    • STEFANI, A., SPADONI, F. & BERNARDI, G. (1997). Differential inhibition by riluzole, lamotrigine and phenytoin of sodium and calcium currents in cortical neurons: implication for neuroprotective strategies. Exp. Neurol., 147, 115-122.
    • (1997) Exp. Neurol. , vol.147 , pp. 115-122
    • Stefani, A.1    Spadoni, F.2    Bernardi, G.3
  • 46
    • 0002223825 scopus 로고
    • Emerging perspective on the mechanism of action of gabapentin
    • TAYLOR, C.P. (1994). Emerging perspective on the mechanism of action of gabapentin. Neurology, 44 (suppl 5): S10-S16.
    • (1994) Neurology , vol.44 , Issue.SUPPL. 5
    • Taylor, C.P.1
  • 47
    • 0028091682 scopus 로고
    • Mechanisms of action of new antiepileptic drugs: Rational design and serendipitous finding
    • UPTON, N. (1994). Mechanisms of action of new antiepileptic drugs: rational design and serendipitous finding. Trends Pharmacol. Sci., 15, 456-463.
    • (1994) Trends Pharmacol. Sci. , vol.15 , pp. 456-463
    • Upton, N.1
  • 48
    • 0028330086 scopus 로고
    • Developments in antiepileptic drug therapy
    • WALKER, M.C. & SANDER, J.W. (1994). Developments in anti-epileptic drug therapy. Curr. Opin. Neurol., 7, 131-139.
    • (1994) Curr. Opin. Neurol. , vol.7 , pp. 131-139
    • Walker, M.C.1    Sander, J.W.2
  • 49
    • 0027977004 scopus 로고
    • Limitation by gabapentin of high-frequency action potential firing by mouse central neurons in cell culture
    • WAMIL, A.W. & MCLEAN, M.J. (1994). Limitation by gabapentin of high-frequency action potential firing by mouse central neurons in cell culture. Epilepsy Res., 17, 1-11.
    • (1994) Epilepsy Res. , vol.17 , pp. 1-11
    • Wamil, A.W.1    McLean, M.J.2
  • 50
    • 0019191524 scopus 로고
    • Fine structure and synaptic connections of the common spiny neuron of the rat neostriatum: A study employing intracellular inject of horse-radish peroxidase
    • WILSON, C.J. & GROVES, P.M. (1980). Fine structure and synaptic connections of the common spiny neuron of the rat neostriatum: a study employing intracellular inject of horse-radish peroxidase. J. Comp. Neurol., 194, 599-615.
    • (1980) J. Comp. Neurol. , vol.194 , pp. 599-615
    • Wilson, C.J.1    Groves, P.M.2
  • 51
    • 0029886175 scopus 로고    scopus 로고
    • The origins of two-state spontaneous membrane potential fluctuations of neostriatal spiny neurons
    • WILSON, C.J. & KAWAGUCHI, Y. (1996). The origins of two-state spontaneous membrane potential fluctuations of neostriatal spiny neurons. J. Neurosci., 16, 2651-2661.
    • (1996) J. Neurosci. , vol.16 , pp. 2651-2661
    • Wilson, C.J.1    Kawaguchi, Y.2
  • 52
    • 0022497683 scopus 로고
    • Phenytoin: Mechanism of its anticonvulsivant action
    • YAARI, Y., SELTZER, M. & PINCUS, J. (1986). Phenytoin: mechanism of its anticonvulsivant action. Ann. Neurol., 20, 171-184.
    • (1986) Ann. Neurol. , vol.20 , pp. 171-184
    • Yaari, Y.1    Seltzer, M.2    Pincus, J.3
  • 53


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