Targacept active conformation search: A new method for predicting the conformation of a ligand bound to its protein target

Journal of Medicinal Chemistry

Volumn 47, Issue 27, 2004, Pages 6831-6839

  Klucik, Josef ^a   Xiao, Yun De ^a   Hammond, Phillip S ^a   Harris, Rebecca ^a   Schmitt, Jeffrey D ^a  

^a TARGACEPT INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

20 EPICALCITRIOL; ALITRETINOIN; COLECALCIFEROL RECEPTOR; INHIBITOR PROTEIN; LEXACALCITOL; R 04; THERMOLYSIN;

ANALYTIC METHOD; ARTICLE; BINDING AFFINITY; BINDING SITE; ENERGY TRANSFER; MOLECULAR MODEL; PROTEIN BINDING; PROTEIN CONFORMATION; RHINOVIRUS; STRUCTURE ACTIVITY RELATION; TARGACEPT ACTIVE CONFORMATION SEARCH; THREE DIMENSIONAL IMAGING; X RAY CRYSTALLOGRAPHY;

BINDING SITES; COMPUTING METHODOLOGIES; CRYSTALLOGRAPHY, X-RAY; DRUG DESIGN; HUMANS; LIGANDS; MOLECULAR CONFORMATION; PROTEINS; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 11144239572     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm049729z     Document Type: Article

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