Sperm chromosomal abnormalities in patients with unexplained recurrent abortions

Archives of Andrology

Volumn 51, Issue 1, 2005, Pages 69-76

  Al Hassan, Saad ^a,b   Hellani, A ^a   Al Shahrani, A ^a   Al Deery, M ^a   Jaroudi, K ^a   Coskun, S ^a  

^a KING FAISAL SPECIALIST HOSPITAL AND RESEARCH CENTER   (Saudi Arabia)

^b MBC 52 ^*  (Saudi Arabia)

Author keywords

Abortion; Chromosome; Cytogenetics; Infertility; Karyotype; Sperm

Indexed keywords

ADULT; ARTICLE; CHROMOSOME 13; CHROMOSOME 18; CHROMOSOME 21; CHROMOSOME ABERRATION; CLINICAL ARTICLE; CYTOGENETICS; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; HUMAN; HUMAN CELL; KARYOTYPE; MALE; PRIORITY JOURNAL; RECURRENT ABORTION; SPERM; SPERMATOGENESIS; X CHROMOSOME; Y CHROMOSOME;

ABORTION, HABITUAL; ADULT; ANEUPLOIDY; CHROMOSOME ABERRATIONS; FEMALE; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; MALE; SPERMATOZOA;

EID: 11144238934     PISSN: 01485016     EISSN: None     Source Type: Journal    
DOI: 10.1080/014850190518062     Document Type: Article

References (35)

1. Barlow AL, Hulten MA (1996): Combined immunocytogenetic and molecular cytogenetic analysis of meiosis I human spermatocytes. Chromosome Res 4:562-573.
2. Bonduelle M, Van Assche E, et al. (2002): Prenatal testing in ICSI pregnancies: incidence of chromosomal anomalies in 1586 karyotypes and relation to sperm parameters. Hum Reprod 17:2600-2614.
3. Boue J, Bou A, Lazar P (1975): Retrospective and prospective epidemiological studies of 1500 karyotyped spontaneous human abortions. Teratology 12:11-26.
4. Brandriff B, Gordon L, et al. (1985): Chromosomes of human sperm: variability among normal individuals. Hum Genet 70:18-24.
5. Carp H, Toder V, et al. (2001): Karyotype of the abortus in recurrent miscarriage. Fertil Steril 75:678-682.
6. Carp HJ, Dirnfeld M, et al. (2004): ART in recurrent miscarriage: preimplantation genetic diagnosis/screening or surrogacy? Hum Reprod Advance Online publication 6 May.
7. Carp H, Feldman B, et al. (2004): Parental karyotype and subsequent live births in recurrent miscarriage. Fertil Steril 81:1296-1301.
8. Carrell DT, Wilcox AL, et al. (2001): Chromosome 15 aneuploidy in the sperm and conceptus of a sibling with variable familial expression of round-headed sperm syndrome. Fertil Steril 76:1258-1260.
9. Carrell DT, Wilcox AL, et al. (2003): Elevated sperm chromosome aneuploidy and apoptosis in patients with unexplained recurrent pregnancy loss. Obstet Gynecol 101:1229-1235.
10. Cupisti S, Conn CM, et al. (2003): Sequential FISH analysis of oocytes and polar bodies reveals aneuploidy mechanisms. Prenat Diagn 23:663-668.
11. Delhanty JD, Handyside AH (1995): The origin of genetic defects in the human and their detection in the preimplantation embryo. Hum Reprod Update 1:201-215.
12. Giorlandino C, Calugi G, et al. (1998): Spermatozoa with chromosomal abnormalities may result in a higher rate of recurrent abortion. Fertil Steril 70:576-577.
13. Harper JC, Robinson F, et al. (1994): Detection of fertilization in embryos with accelerated cleavage by fluorescent in-situ hybridization (FISH). Hum Reprod 9:1733-1737.
14. Holmes JM, Martin RH (1993): Aneuploidy detection in human sperm nuclei using fluorescence in situ hybridization. Hum Genet 91:20-24.
15. Kahraman S, Benkhalifa M, et al. (2004): The results of aneuploidy screening in 276 couples undergoing assisted reproductive techniques. Prenat Diagn 24:307-311.
16. Kruger TF, Acosta AA, et al. (1987): New method of evaluating sperm morphology with predictive value for human in vitro fertilization. Urology: 30:248-251.
17. Kurahashi H, Emanuel BS (2001): Unexpectedly high rate of de novo constitutional t(11;22) translocations in sperm from normal males. Nat Genet 29:139-140.
18. Lathi RB, Milki AA (2004): Rate of aneuploidy in miscarriages following in vitro fertilization and intracytoplasmic sperm injection. Fertil Steril 81:1270-1272.
19. Lee RM, Silver RM (2000): Recurrent pregnancy loss: summary and clinical recommendations. Semin Reprod Med 18:433-440.
20. Marchetti F, Bishop JB, et al. (2004): Paternally transmitted chromosomal aberrations in mouse zygotes determine their embryonic fate. Biol Reprod 70:616-624.
21. Mroz K, Hassold TJ, Hunt PA (1999): Meiotic aneuploidy in the XXY mouse: evidence that a compromised testicular environment increases the incidence of meiotic errors. Hum Reprod 14:1151-1156.
22. Ogasawara M, Aoki K, et al. (2000): Embryonic karyotype of abortuses in relation to the number of previous miscarriages. Fertil Steril 73:300-304.
23. Pang MG, Hoegerman SF, et al. (1999): Detection of aneuploidy for chromosomes 4, 6, 7, 8, 9, 10, 11, 12, 13, 17, 18, 21, X and Y by fluorescence in-situ hybridization in spermatozoa from nine patients with oligoasthenoteratozoospermia undergoing intracytoplasmic sperm injection. Hum Reprod 14:1266-1273.
24. Pellicer A, Rubio C, et al. (1999): In vitro fertilization plus preimplantation genetic diagnosis in patients with recurrent miscarriage: an analysis of chromosome abnormalities in human preimplantation embryos. Fertil Steril 71:1033-1039.
25. Remohi J, Gallardo E, et al. (1996): Oocyte donation in women with recurrent pregnancy loss. Hum Reprod 11:2048-2051.
26. Rosenbusch B, Sterzik K (1991): Sperm chromosomes and habitual abortion. Fertil Steril 56:370-372.
27. Rubio C, Simon C, et al. (1999): Implications of sperm chromosome abnormalities in recurrent miscarriage. J Assist Reprod Genet 16:253-258.
28. Rubio C, Simon C, et al. (2003): Chromosomal abnormalities and embryo development in recurrent miscarriage couples. Hum Reprod 18:182-188.
29. Sbracia M, Baldi M, et al. (2002): Preferential location of sex chromosomes, their aneuploidy in human sperm, and their role in determining sex chromosome aneuploidy in embryos after ICSI. Hum Reprod 17:320-324.
30. Stephenson MD, Awartani KA, Robinson WP (2002): Cytogenetic analysis of miscarriages from couples with recurrent miscarriage: a case-control study. Hum Reprod 17:446-451.
31. Tang SS, Gao H, et al. (2004): An association between sex chromosomal aneuploidy in sperm and an abortus with 45,X of paternal origin: possible transmission of chromosomal abnormalities through ICSI. Hum Reprod 19:147-151.
32. Tulppala M, Palosuo T, et al. (1993): A prospective study of 63 couples with a history of recurrent spontaneous abortion: contributing factors and outcome of subsequent pregnancies. Hum Reprod 8:764-770.
33. Van Opstal D, Los FJ, et al. (1997): Determination of the parent of origin in nine cases of prenatally detected chromosome aberrations found after intracytoplasmic sperm injection. Hum Reprod 12:682-686.
34. Wilding M, Forman R, et al. (2004): Preimplantation genetic diagnosis for the treatment of failed in vitro fertilization-embryo transfer and habitual abortion. Fertil Steril 81:1302-1307.
35. Zenzes MT, Casper RF (1992): Cytogenetics of human oocytes, zygotes, and embryos after in vitro fertilization. Hum Genet 88:367-375.