Conformation and activity of δ-lysin and its analogs

Peptides

Volumn 26, Issue 2, 2005, Pages 217-225

  Dhople, Vishnu M ^a   Nagaraj, Ramakrishnan ^a  

^a CENTRE FOR CELLULAR AND MOLECULAR BIOLOGY   (India)

Author keywords

Alpha helix; Antibacterial activity; Hemolytic activity; Peptide conformation; Synthetic peptides; Toxin

Indexed keywords

ALANYLGLUTAMINYLASPARTYLISOLEUCYLISOLEUCYLSERYLTHREONYLISOLEUCYLGLYCYL ASPARTYLLEUCYLPROLYLLYSYLTRYPTOPHYLISOLEUCYLISOLEUCYLASPARTYLTHREONYLVALYL ASPARAGINYLLYSYLPHENYLALANYLTHREONYLLYSYLLYSINE; ALANYLGLUTAMINYLASPARTYLISOLEUCYLISOLEUCYLSERYLTHREONYLISOLEUCYLGLYCYL ASPARTYLLEUCYLVALYLLYSYLTRYPTOPHYLISOLEUCYLISOLEUCYLASPARTYLTHREONYLVALYL ASPARAGINYLLYSYLPHENYLALANYLTHREONYLLYSYLLYSINE; ALANYLGLUTAMINYLLYSYLISOLEUCYLISOLEUCYLSERYLTHREONYLISOLEUCYLGLYCYLLYSYL LEUCYLPROLYLLYSYLTRYPTOPHYLISOLEUCYLISOLEUCYLLYSYLTHREONYLVALYLASPARAGINYLLYSYL PHENYLALANYLTHREONYLLYSYLLYSINE; ALANYLGLUTAMINYLLYSYLISOLEUCYLISOLEUCYLSERYLTHREONYLISOLEUCYLGLYCYLLYSYL LEUCYLVALYLLYSYLTRYPTOPHYLISOLEUCYLISOLEUCYLLYSYLTHREONYLVALYLASPARAGINYLLYSYL PHENYLALANYLTHREONYLLYSYLLYSINE; ANION; ASPARTYLLEUCYLPROLYLLYSYLTRYPTOPHYLISOLEUCYLISOLEUCYLASPARTYLTHREONYLVALYL ASPARAGINYLLYSYLPHENYLALANYLTHREONYLLYSYLLYSINE; ASPARTYLLEUCYLVALYLLYSYLTRYPTOPHYLISOLEUCYLISOLEUCYLASPARTYLTHREONYLVALYL ASPARAGINYLLYSYLPHENYLALANYLTHREONYLLYSYLLYSINE; BACTERIAL TOXIN; CATION; DELTA LYSIN; ISOLEUCYLGLYCYLASPARTYLLEUCYLPROLYLLYSYLTRYPTOPHYLISOLEUCYLISOLEUCYL ASPARTYLTHREONYLVALYLASPARAGINYLLYSYLPHENYLALANYLTHREONYLLYSYLLYSINE; ISOLEUCYLGLYCYLASPARTYLLEUCYLVALYLLYSYLTRYPTOPHYLISOLEUCYLISOLEUCYL ASPARTYLTHREONYLVALYLASPARAGINYLLYSYLPHENYLALANYLTHREONYLLYSYLLYSINE; ISOLEUCYLGLYCYLLYSYLLEUCYLPROLYLLYSYLTRYPTOPHYLISOLEUCYLISOLEUCYLLYSYL THREONYLVALYLASPARAGINYLLYSYLPHENYLALANYLTHREONYLLYSYLLYSINE; ISOLEUCYLGLYCYLLYSYLLEUCYLVALYLLYSYLTRYPTOPHYLISOLEUCYLISOLEUCYLLYSYL THREONYLVALYLASPARAGINYLLYSYLPHENYLALANYLTHREONYLLYSYLLYSINE; ISOLEUCYLISOLEUCYLSERYLTHREONYLISOLEUCYLGLYCYLASPARTYLLEUCYLPROLYLLYSYL TRYPTOPHYLISOLEUCYLISOLEUCYLASPARTYLTHREONYLVALYLASPARAGINYLLYSYLPHENYLALANYL THREONYLLYSYLLYSINE; ISOLEUCYLISOLEUCYLSERYLTHREONYLISOLEUCYLGLYCYLASPARTYLLEUCYLVALYLLYSYL TRYPTOPHYLISOLEUCYLISOLEUCYLASPARTYLTHREONYLVALYLASPARAGINYLLYSYLPHENYLALANYL THREONYLLYSYLLYSINE; ISOLEUCYLISOLEUCYLSERYLTHREONYLISOLEUCYLGLYCYLLYSYLLEUCYLPROLYLLYSYL TRYPTOPHYLISOLEUCYLISOLEUCYLLYSYLTHREONYLVALYLASPARAGINYLLYSYLPHENYLALANYL THREONYLLYSYLLYSINE; ISOLEUCYLISOLEUCYLSERYLTHREONYLISOLEUCYLGLYCYLLYSYLLEUCYLVALYLLYSYL TRYPTOPHYLISOLEUCYLISOLEUCYLLYSYLTHREONYLVALYLASPARAGINYLLYSYLPHENYLALANYL THREONYLLYSYLLYSINE; LYSYLLEUCYLPROLYLLYSYLTRYPTOPHYLISOLEUCYLISOLEUCYLLYSYLTHREONYLVALYL ASPARAGINYLLYSYLPHENYLALANYLTHREONYLLYSYLLYSINE; LYSYLLEUCYLVALYLLYSYLTRYPTOPHYLISOLEUCYLISOLEUCYLLYSYLTHREONYLVALYL ASPARAGINYLLYSYLPHENYLALANYLTHREONYLLYSYLLYSINE; METHIONYLALANYLGLUTAMINYLASPARTYLISOLEUCYLISOLEUCYLSERYLTHREONYLISOLEUCYL GLYCYLASPARTYLLEUCYLPROLYLLYSYLTRYPTOPHYLISOLEUCYLISOLEUCYLASPARTYLTHREONYL VALYLASPARAGINYLLYSYLPHENYLALANYLTHREONYLLYSYLLYSINE; METHIONYLALANYLGLUTAMINYLASPARTYLISOLEUCYLISOLEUCYLSERYLTHREONYLISOLEUCYL GLYCYLASPARTYLLEUCYLVALYLLYSYLTRYPTOPHYLISOLEUCYLISOLEUCYLASPARTYLTHREONYLVALYL ASPARAGINYLLYSYLPHENYLALANYLTHREONYLLYSYLLYSINE; METHIONYLALANYLGLUTAMINYLLYSYLISOLEUCYLISOLEUCYLSERYLTHREONYLISOLEUCYL GLYCYLLYSYLLEUCYLPROLYLLYSYLTRYPTOPHYLISOLEUCYLISOLEUCYLLYSYLTHREONYLVALYL ASPARAGINYLLYSYLPHENYLALANYLTHREONYLLYSYLLYSINE; METHIONYLALANYLGLUTAMINYLLYSYLISOLEUCYLISOLEUCYLSERYLTHREONYLISOLEUCYL GLYCYLLYSYLLEUCYLVALYLLYSYLTRYPTOPHYLISOLEUCYLISOLEUCYLLYSYLTHREONYLVALYL ASPARAGINYLLYSYLPHENYLALANYLTHREONYLLYSYLLYSINE; POLYPEPTIDE ANTIBIOTIC AGENT; SERYLTHREONYLISOLEUCYLGLYCYLASPARTYLLEUCYLPROLYLLYSYLTRYPTOPHYLISOLEUCYL ISOLEUCYLASPARTYLTHREONYLVALYLASPARAGINYLLYSYLPHENYLALANYLTHREONYLLYSYLLYSINE; SERYLTHREONYLISOLEUCYLGLYCYLASPARTYLLEUCYLVALYLLYSYLTRYPTOPHYLISOLEUCYL ISOLEUCYLASPARTYLTHREONYLVALYLASPARAGINYLLYSYLPHENYLALANYLTHREONYLLYSYLLYSINE; SERYLTHREONYLISOLEUCYLGLYCYLLYSYLLEUCYLPROLYLLYSYLTRYPTOPHYLISOLEUCYL ISOLEUCYLLYSYLTHREONYLVALYLASPARAGINYLLYSYLPHENYLALANYLTHREONYLLYSYLLYSINE; SERYLTHREONYLISOLEUCYLGLYCYLLYSYLLEUCYLVALYLLYSYLTRYPTOPHYLISOLEUCYL ISOLEUCYLLYSYLTHREONYLVALYLASPARAGINYLLYSYLPHENYLALANYLTHREONYLLYSYLLYSINE; UNCLASSIFIED DRUG; WATER;

ALPHA HELIX; AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANTIBACTERIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG CONFORMATION; DRUG DETERMINATION; DRUG SYNTHESIS; GENE DELETION; GUINEA PIG; HEMOLYSIS; LYSIS; NONHUMAN; OBSERVATION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DETERMINATION;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; CIRCULAR DICHROISM; DOSE-RESPONSE RELATIONSHIP, DRUG; ERYTHROCYTES; ESCHERICHIA COLI; GUINEA PIGS; HEMOLYSIN PROTEINS; LYSINE; MICROBIAL SENSITIVITY TESTS; MOLECULAR CONFORMATION; MOLECULAR SEQUENCE DATA; PEPTIDES; PROLINE; PROTEIN STRUCTURE, SECONDARY; SEQUENCE DELETION; STAPHYLOCOCCUS AUREUS; STRUCTURE-ACTIVITY RELATIONSHIP;

APOIDEA; STAPHYLOCOCCUS AUREUS;

EID: 11144237946     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.peptides.2004.09.013     Document Type: Article

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