Appropriateness of breast-conserving treatment of breast carcinoma in women with germline mutations in BRCA1 or BRCA2: A clinic-based series

Cancer

Volumn 103, Issue 1, 2005, Pages 44-51

  Robson, Mark ^a   Svahn, Tiffany ^a,b   McCormick, Beryl ^a   Borgen, Patrick ^a   Hudis, Clifford A ^a   Norton, Larry ^a   Offit, Kenneth ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b STANFORD UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Breast carcinoma; Genetic predisposition; Lumpectomy; Radiation therapy

Indexed keywords

BRCA1 PROTEIN; BRCA2 PROTEIN; TAMOXIFEN;

ADULT; AGED; ARTICLE; AXILLARY LYMPH NODE; BREAST CARCINOMA; CANCER RADIOTHERAPY; COHORT ANALYSIS; CONTROLLED STUDY; FAMILY HISTORY; FEMALE; FOLLOW UP; GENETIC PREDISPOSITION; HUMAN; HUMAN TISSUE; KAPLAN MEIER METHOD; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MUTATION; ONCOGENE; PARTIAL MASTECTOMY; PRIORITY JOURNAL; PROSPECTIVE STUDY;

ADULT; AGED; AGED, 80 AND OVER; BREAST NEOPLASMS; CARCINOMA; FEMALE; FOLLOW-UP STUDIES; GENES, BRCA1; GENES, BRCA2; GERM-LINE MUTATION; HUMANS; MASTECTOMY; MASTECTOMY, SEGMENTAL; MIDDLE AGED; NEOPLASMS, SECOND PRIMARY; PATIENT SELECTION; PROGNOSIS; RISK FACTORS;

EID: 10844296769     PISSN: 0008543X     EISSN: None     Source Type: Journal    
DOI: 10.1002/cncr.20728     Document Type: Article

References (27)

1. Miki Y, Swensen J, Shattuck-Eidens D, et al. A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1. Science. 1994;266:66-71.
2. Wooster R, Bignell G, Lancaster J, et al. Identification of the breast cancer susceptibility gene BRCA2. Nature. 1995;378:789-792.
3. Pierce L. Radiotherapy for breast cancer in BRCA1/BRCA2 carriers: clinical issues and management dilemmas. Semin Radiat Oncol. 2002;12:352-361.
4. Foulkes WD, Wong N, Brunet JS, et al. Germ-line BRCA1 mutation is an adverse prognostic factor in Ashkenazi Jewish women with breast cancer. Clin Cancer Res. 1997;3:2465-2469.
5. Gaffney DK, Brohet RM, Lewis CM, et al. Response to radiation therapy and prognosis in breast cancer patients with BRCA1 and BRCA2 mutations. Radiother Oncol. 1998;47:129-136.
6. Verhoog LC, Brekelmans CT, Seynaeve C, et al. Survival and tumour characteristics of breast-cancer patients with germline mutations of BRCA1. Lancet. 1998;351:316-321.
7. Robson M, Levin D, Federici M, et al. Breast conservation therapy for invasive breast cancer in Ashkenazi women with BRCA gene founder mutations. J Natl Cancer Inst. 1999;91:2112-2117.
8. Pierce LJ, Strawderman M, Narod SA, et al. Effect of radiotherapy after breast-conserving treatment in women with breast cancer and germline BRCA1/2 mutations. J Clin Oncol 2000;18:3360-3369.
9. Pierce L, Levin A, Rebbeck T, et al. Ten-year outcome of breast-conserving surgery (BCS) and radiotherapy (RT) in women with breast cancer (BC) and germline BRCA 1/2 mutations: results from an international collaboration [abstract]. Breast Cancer Res Treat. 2003;82:S7.
10. Delaloge S, Kloos I, Ariane D, et al. Young age is the major predictor of local relapse among conservatively treated BRCA1-, BRCA2-, or non-BRCA-linked hereditary breast cancer (BC) [abstract]. Proc Am Soc Clin Oncol. 2003;22:11.
11. Robson ME, Chappuis PO, Satagopan J, et al. A combined analysis of outcome following breast cancer: differences in survival based on BRCA1/BRCA2 mutation status and administration of adjuvant treatment. Breast Cancer Res. 2004;6:R8-R17.
12. Metcalfe K, Lynch HT, Ghadirian P, et al. Contralateral breast cancer in BRCA1 and BRCA2 mutation carriers. J Clin Oncol. 2004;22:2328-2335.
13. Turner BC, Harrold E, Matloff E, et al. BRCA1/BRCA2 germline mutations in locally recurrent breast cancer patients after lumpectomy and radiation therapy: implications for breast-conserving management in patients with BRCA1/BRCA2 mutations. J Clin Oncol. 1999;17:3017-3024.
14. Haffty BG, Harrold E, Khan AJ, et al. Outcome of conservatively managed early-onset breast cancer by BRCA1/2 status. Lancet. 2002;359:1471-1477.
15. Bremer M, Doerk T, Sohn C, Karstens JH. Local relapse after post-operative radiotherapy in patients with bilateral breast cancer by BRCA1/2 status [abstract]. Proc Am Soc Clin Oncol. 2003;22:11.
16. Seynaeve C, Verhoog LC, van de Bosch LM, et al. Ipsilateral breast tumour recurrence in hereditary breast cancer following breast-conserving therapy. Eur J Cancer. 2004;40:1150-1158.
17. Singletary SE, Allred C, Ashley P, et al. Revision of the American Joint Committee on Cancer staging system for breast cancer. J Clin Oncol. 2002;20:3628-3636.
18. Chabner E, Nixon A, Gelman R, et al. Family history and treatment outcome in young women after breast-conserving surgery and radiation therapy for early-stage breast cancer. J Clin Oncol 1998;16:2045-2051.
19. Freedman LM, Buchholz TA, Thames HD, et al. Local-regional control in breast cancer patients with a possible genetic predisposition. Int J Radiat Oncol Biol Phys. 2000;48:951-957.
20. Haas JA, Schultz DJ, Peterson ME, Solin LJ. An analysis of age and family history on outcome after breast-conservation treatment: the University of Pennsylvania experience. Cancer J Sci Am. 1998;4:308-315.
21. Harrold EV, Turner BC, Matloff ET, et al. Local recurrence in the conservatively treated breast cancer patient: a correlation with age and family history. Cancer J Sci Am. 1998;4:302-307.
22. Simmonds P, Eccles D, Goddard J, Evans G, Lalloo F, Royle G. Is breast conservation appropriate for women with hereditary breast cancer [abstract]? Proc Am Soc Clin Oncol 1999;18:612a.
23. Vlastos G, Mirza NQ, Meric F, et al. Breast-conservation therapy in early-stage breast cancer patients with a positive family history. Ann Surg Oncol. 2002;9:912-919.
24. Verhoog LC, Brekelmans CT, Seynaeve C, Meijers-Heijboer EJ, Klijn JG. Contralateral breast cancer risk is influenced by the age at onset in BRCA1-associated breast cancer. Br J Cancer. 2000;83:384-386.
25. Foulkes WD, Wong N, Brunei JS, Narod SA. BRCA mutations and survival in breast cancer. J Clin Oncol. 1998;16:3206-3208.
26. Foulkes WD, Wong N, Rozen F, Brunei JS, Narod SA. Survival of patients with breast cancer and BRCA1 mutations. Lancet. 1998;351:1359-1360.
27. Robson M, Gilewski T, Haas B, et al. BRCA-associated breast cancer in young women. J Clin Oncol. 1998;16:1642-1649.