Local-regional control in breast cancer patients with a possible genetic predisposition

International Journal of Radiation Oncology Biology Physics

Volumn 48, Issue 4, 2000, Pages 951-957

  Freedman, Laura M ^a   Buchholz, Thomas A ^a   Thames, Howard D ^a   Strom, Eric A ^a   McNeese, Marsha D ^a   Hortobagyi, Gabriel N ^a   Singletary, S Eva ^a   Heaton, Keith M ^a,b   Hunt, Kelly K ^b  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

Breast cancer; Breast conservation therapy; Genetic predisposition; Radiation

Indexed keywords

DOXORUBICIN;

ADJUVANT CHEMOTHERAPY; AGED; ARTICLE; BILATERAL CANCER; BREAST CANCER; CONSERVATIVE TREATMENT; DERMATOFIBROMA; FAMILY HISTORY; FEMALE; GENE MUTATION; GENETIC PREDISPOSITION; HISTOLOGY; HORMONAL THERAPY; HUMAN; LUNG CANCER; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MASTECTOMY; OVARY CANCER; PRIORITY JOURNAL; RECURRENCE RISK; RETROSPECTIVE STUDY; STOMACH CANCER; SURGICAL TECHNIQUE; SURVIVAL RATE; THYROID CANCER;

ADULT; AGED; AGED, 80 AND OVER; BREAST NEOPLASMS; FAMILY; FEMALE; FOLLOW-UP STUDIES; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MASTECTOMY, RADICAL; MASTECTOMY, SEGMENTAL; MIDDLE AGED; MULTIVARIATE ANALYSIS; NEOPLASM RECURRENCE, LOCAL; NEOPLASMS, MULTIPLE PRIMARY; PROPORTIONAL HAZARDS MODELS; RETROSPECTIVE STUDIES;

EID: 0034333022     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0360-3016(00)00761-6     Document Type: Article

References (24)

1. Patterns of allele losses suggest the existence of five distinct regions of LOH on chromosome 17 in breast cancer
2. Consistent loss of the wild type allele in breast cancers from a family linked to the BRCA2 gene on chromosome 13q12-13
3. Nonparametric estimation from incomplete observations
4. BRCA1 sequence analysis in women at high risk for susceptibility mutations
5. Family history and treatment outcome in young women after breast-conserving surgery and radiation therapy for early-stage cancer
6. An analysis of age and family history on outcome after breast-conservation treatment; The University of Pennsylvania experience
7. Local recurrence in the conservatively treated breast cancer patient; A correlation with age and family history
8. BRCA1/BRCA2 germline mutations in locally recurrent breast cancer patients after lumpectomy and radiation therapy; Implications for breast-conserving management in patients with BRCA1/BRCA2 mutations
9. Breast conservation therapy for invasive breast cancer in Ashkenazi women with BRCA gene founder mutations
10. Frequency of p53 mutations in breast carcinomas from Ashkenazi Jewish carriers of BRCA1 mutations
11. Survival of BRCA1 breast and ovarian cancer patients; A population-based study from southern Sweden
12. Survival after breast cancer in Ashkenazi Jewish BRCA1 and BRCA2 mutation carriers
13. Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2
14. BRCA1 required for transcription-coupled repair of oxidative DNA damage
15. Association of BRCA1 with the hRad50-hMre11-p95 complex and the DNA damage response
16. Cells deleted for Brca2 COOH terminus exhibit hypersensitivity to γ-radiation and premature senescence
17. Fibroblasts for ataxia telangiectasia (AT) and AT heterozygotes show an enhanced level of residual DNA double-strand breaks after low dose-rate γ-irradiation as assayed by pulsed field gel electrophoresis
18. Antisense RNA to the putative tumor suppressor gene BRCA1 transforms mouse fibroblasts