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Volumn 5, Issue 12, 2004, Pages 1710-1712

A biomimetic model of tandem radical damage involving sulfur-containing proteins and unsaturated lipids

Author keywords

Isomerization; Lipids; Liposomes; Protein damage; Radicals; Raman spectroscopy

Indexed keywords

DIOLEOYLPHOSPHATIDYLCHOLINE; LIPOSOME; METHIONINE; PROTEIN; RADICAL; RIBONUCLEASE A; SULFUR; THIYL RADICAL; UNCLASSIFIED DRUG; UNSATURATED FATTY ACID; WATER;

EID: 10844270510     PISSN: 14394227     EISSN: None     Source Type: Journal    
DOI: 10.1002/cbic.200400250     Document Type: Article
Times cited : (24)

References (30)
  • 15
    • 10844259148 scopus 로고    scopus 로고
    • note
    • -1 bands decreased substantially; this is associated with the tyrosines residues.[9] The conformational changes of RNase A were evaluated by using a method based on a combination of X-ray determined structures and Raman data.[10] After 23 Gy of irradiation, the α-helix percentage decreased from 18% to about 12% and the β-sheet percentage increased from about 48% to 54%. Increasing the dose to 61 Gy did not cause further conformational changes. It is worth noting that Met13, Met29, and Met30 are located in the α1 and α2 helices.
  • 16
    • 0002660213 scopus 로고
    • Eds.: R. J. H. Clark, R. E. Hester) Wiley, Chichester
    • A. Tu in Spectroscopy of Biological Systems, Vol. 13 (Eds.: R. J. H. Clark, R. E. Hester) Wiley, Chichester, 1986, pp. 47-112.
    • (1986) Spectroscopy of Biological Systems , vol.13 , pp. 47-112
    • Tu, A.1
  • 18
    • 10844249503 scopus 로고    scopus 로고
    • note
    • Amino acid analysis and proteolytic mapping in conjunction with mass spectrometry is in progress.
  • 23
    • 10844291004 scopus 로고    scopus 로고
    • note
    • Three of the four methionines in RNase A are partially exposed on the surface.
  • 24
    • 10844289826 scopus 로고    scopus 로고
    • note
    • -1, respectively;
  • 25
    • 10844261883 scopus 로고    scopus 로고
    • note
    • -1, respectively.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.