Production of a mouse/human chimeric IgE monoclonal antibody to the house dust mite allergen Der p 2 and its use for the absolute quantification of allergen-specific IgE

Journal of Allergy and Clinical Immunology

Volumn 99, Issue 4, 1997, Pages 545-550

  Schuurman, Janine ^a   Perdok, Gerrard J ^a   Lourens, Tom E ^a   Parren, Paul W H I ^b   Chapman, Martin D ^c   Aalberse, Rob C ^a,d  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c UNIVERSITY OF VIRGINIA   (United States)

^d CENTRAL LABORATORY   (Netherlands)

Author keywords

allergen specific IgE; chimeric antibody; Der p 2; house dust mite; IgE; RAST

Indexed keywords

HOUSE DUST ALLERGEN; IMMUNOGLOBULIN E ANTIBODY; IMMUNOGLOBULIN G ANTIBODY; MONOCLONAL ANTIBODY;

ALLERGENICITY; ALLERGY; ANIMAL CELL; ANTIBODY SPECIFICITY; ARTICLE; CELL CULTURE; CHIMERA; DERMATOPHAGOIDES PTERONYSSINUS; HOUSE DUST; HUMAN; HUMAN CELL; HYBRIDOMA; MITE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RADIOALLERGOSORBENT TEST; RADIOIMMUNOASSAY;

EID: 0030956696     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0091-6749(97)70083-6     Document Type: Article

References (16)

1. Wide L, Bennich H, Johansson SGO. Diagnosis of allergy by an in-vitro test for allergen antibodies. Lancet 1967;ii:1105-7.
2. Lind P. Purification and partial characterization of two major allergens from the house dust mite Dermatophagoides pteronyssinus. J Allergy Clin Immunol 1985;76:753-61.
3. Ovsyannikova IG, Vailes LD, Li Y, Heymann PW, Chapman MD. Monoclonal antibodies to group II Dermatophagoides spp. allergens: murine immune response, epitope analysis, and development of a two-site ELISA. J Allergy Clin Immunol 1994;94:537-46.
4. Flanagan JG, Rabbitts TH. The sequence of a human immunoglobulin epsilon heavy chain constant region gene, and evidence for three non-allelic genes. EMBO J 1982;1:655-60.
5. Flanagan JG, Rabbitts TH. Arrangement of human immunoglobulin heavy chain constant region genes implies evolutionary duplication of a segment containing gamma, epsilon and alpha genes. Nature 1982;300:709-13.
6. Brakenhoff JPJ, De Groot ER, Evers RF, Pannekoek H, Aarden LA. Molecular cloning and expression of hybridoma growth factor in Escherichia coli. J Immunol 1987;139:4116-21.
7. Neuberger MS, Williams GT, Mitchell EB, Jouhal SS, Flanagan JG, Rabbitts TH. A hapten-specific chimaeric IgE antibody with human physiological effector function. Nature 1985;314:268-70.
8. Parren PWHI, Geerts MEJ, Boeije LCM, Aarden LA. Induction of T-cell proliferation by recombinant mouse and chimeric mouse/ human anti-CD3 monoclonal antibodies. Res Immunol 1991;142:749-63.
9. Orlandi R, Guessow DH, Jones PT, Winter G. Cloning immunoglobulin variable domains for expression by the polymerase chain reaction. Proc Natl Acad Sci U S A 1989;86:3833-7.
10. Sambrook J, Fritsch EF, Maniatis T. Molecular cloning: a laboratory manual. New York: Cold Spring Harbor Laboratory Press, 1989.
11. Brüggemann M, Williams GT, Bindon CI, et al. Comparison of the effector functions of human immunoglobulins using a matched set of chimeric antibodies. J Exp Med 1987;166:1351-61.
12. Boot JHA, Parren PWHI, Geerts MEJ, Aarden LA. Spontaneous generation of antibody isotype heterogeneity during long-term cul-tivation of hybridoma cells [PhD thesis]. Amsterdam: University of Amsterdam, 1989:47.
13. Boot JHA, Geerts MET, De Groot ER, Aarden LA. Murine monoclonal isotype switch variants: detection with rat monoclonal antibodies in ELISA and isolation by sequential sublining. J Immunol Methods 1988;106:95-202.
14. Southern PJ, Berg P. Transformation of mammalian cells to antibi-otic resistance with a bacterial gene under control of the SV40 early region promotor. J Mol Appl Genet 1982;1:327-41.
15. Aalberse RC, Koshte V, Clemens JGJ. Immunoglobulin E antibodies that crossreact with vegetable foods, pollen, and Hymenoptera venom. J Allergy Clin Immunol 1981;68:356-64.
16. Bazaral M, Hamburger RN. Standardization and stability of immunoglobulin E (IgE). J Allergy Clin Immunol 1972;49:189-91.