Substrate range of acetohydroxy acid synthase I from Escherichia coli in the stereoselective synthesis of α-hydroxy ketones

Biotechnology and Bioengineering

Volumn 88, Issue 7, 2004, Pages 825-831

  Engel, Stanislav ^a   Vyazmensky, Maria ^a   Berkovich, Dvora ^a   Barak, Ze'ev ^a   Chipman, David M ^a  

^a BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

Author keywords

Acetolactate synthase; Aromatic aldehydes; Chiral synthon; Pyruvate; Quantitative structure activity relationship; Thiamine diphosphate

Indexed keywords

ALDEHYDES; ESCHERICHIA COLI; KETONES; ORGANIC ACIDS; SYNTHESIS (CHEMICAL);

BENZALDEHYDES; BIOSYNTHETIC PLATFORMS; ELECTRONIC EFFECTS; LIPOPHILICITY;

ENZYMES;

ACETOLACTATE SYNTHASE; ALDEHYDE; ALPHA HYDROXY KETONE DERIVATIVE; BENZALDEHYDE; BENZALDEHYDE DERIVATIVE; ISOENZYME; KETONE DERIVATIVE; METHANOL DERIVATIVE; PYRUVIC ACID; UNCLASSIFIED DRUG;

ARTICLE; BIOSYNTHESIS; CHEMICAL REACTION; CHIRALITY; ENZYME SUBSTRATE; ESCHERICHIA COLI; LIPOPHILICITY; NONHUMAN; QUANTITATIVE STRUCTURE ACTIVITY RELATION; STEREOCHEMISTRY; SUBSTITUTION REACTION; SYNTHESIS;

ACETOLACTATE SYNTHASE; ALDEHYDES; ENZYME ACTIVATION; ESCHERICHIA COLI; KETONES; KINETICS; SENSITIVITY AND SPECIFICITY; STEREOISOMERISM; SUBSTRATE SPECIFICITY;

ESCHERICHIA COLI;

EID: 10844256591     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/bit.20275     Document Type: Article

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