Detection of gyrA and parC mutations associated with ciprofloxacin resistance in Neisseria gonorrhoeae by use of oligonucleotide biochip technology

Journal of Clinical Microbiology

Volumn 42, Issue 12, 2004, Pages 5819-5824

  Zhou, Wenming ^a   Du, Weidong ^a   Cao, Huimin ^b   Zhao, Jianlong ^b   Yang, Sen ^a   Li, Wei ^a   Shen, Yujun ^a   Zhang, Shumei ^a   Du, Wenhui ^a   Zhang, Xuejun ^a  

^a ANHUI MEDICAL UNIVERSITY   (China)

^b INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; CIPROFLOXACIN; DNA TOPOISOMERASE (ATP HYDROLYSING) A; PROTEIN PARC;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL GENE; BACTERIAL GENETICS; BACTERIAL STRAIN; CHINA; DISCRIMINANT ANALYSIS; DNA HYBRIDIZATION; DNA MICROARRAY; DNA SEQUENCE; GENETIC ASSOCIATION; GENETIC EPIDEMIOLOGY; GENETIC STRAIN; NEISSERIA GONORRHOEAE; NONHUMAN; NUCLEOTIDE SEQUENCE; OLIGONUCLEOTIDE PROBE; POINT MUTATION; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY;

ANTI-INFECTIVE AGENTS; CHINA; CIPROFLOXACIN; DNA GYRASE; DNA TOPOISOMERASE IV; DRUG RESISTANCE, BACTERIAL; GONORRHEA; HUMANS; MICROBIAL SENSITIVITY TESTS; NEISSERIA GONORRHOEAE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; POINT MUTATION; SENSITIVITY AND SPECIFICITY; SEQUENCE ANALYSIS, DNA;

BACTERIA (MICROORGANISMS); NEGIBACTERIA; NEISSERIA; NEISSERIA GONORRHOEAE;

EID: 10844245354     PISSN: 00951137     EISSN: None     Source Type: Journal    
DOI: 10.1128/JCM.42.12.5819-5824.2004     Document Type: Article

References (28)

1. Alcala, B., L. Arreaza, C. Salcedo, I. Antolin, N. Borrell, J. Cacho, C. De Las Cuevas, L. Otero, G. Sauca, F. Vazquez, H. Villar, and J. A. Vazquez. 2003. Molecular characterization of ciprofloxacin resistance of gonococcal strains in Spain. Sex. Transm. Dis. 30:395-398.
2. Belland, R. J., S. G. Morrison, C. Ison, and W. M. Huang. 1994. Neisseria gonorrhoeae acquires mutations in analogous regions of gyrA and parC in fluoroquinolone-resistant isolates. Mol. Microbiol. 14:371-380.
3. Booth, S. A., M. A. Drebot, I. E. Martin, and L. K. Ng. 2003. Design of oligonucleotide arrays to detect point mutations: molecular typing of antibiotic resistant strains of Neisseria gonorrhoeae and hantavirus infected deer mice. Mol. Cell. Probes 17:77-84.
4. Call, D. R., M. K. Borucki, and F. J. Loge. 2003. Detection of bacterial pathogens in environmental samples using DNA microarrays. J. Microbiol. Methods 53:235-243.
5. Cheung, V. G., M. Morley, F. Aguilar, A. Massimi, R. Kucherlapati, and G. Childs. 1999. Making and reading microarrays. Nat. Genet. 21:15-19.
6. Corkill, J. E., A. Percival, and M. Lind. 1991. Reduced uptake of ciprofloxacin in a resistant strain of Neisseria gonorrhoeae and transformation of resistance to other strains. J. Antimicrob. Chemother. 28:601-604.
7. Deguchi, T., M. Yasuda, M. Asano, K. Tada, H. Iwata, H. Komeda, T. Ezaki, I. Saito, and Y. Kawada. 1995. DNA gyrase mutations in quinolone-resistant clinical isolates of Neisseria gonorrhoeae. Antimicrob. Agents Chemother. 39:561-563.
8. Deguchi, T., M. Yasuda, M. Nakano, S. Ozeki, T. Ezaki, I. Saito, and Y. Kawada. 1996. Quinolone-resistant Neisseria gonorrhoeae: correlation of alterations in the GyrA subunit of DNA gyrase and the ParC subunit of topoisomerase IV with antimicrobial susceptibility profiles. Antimicrob. Agents Chemother. 40:1020-1023.
9. Du, W., C. Marsac, M. Kruschina, F. Ortigao, and C. Florentz. 2003. Functionalized self-assembled monolayer on gold for detection of human mitochondrial tRNA gene mutations. Anal. Biochem. 322:14-25.
10. Du, W., Z. Xu, X. Ma, L. Song, and E. M. Schneider. 2003. Biochip as a potential platform of serological interferon alpha2b antibody assay. J. Biotechnol. 106:87-100.
11. Fodde, R., and M. Losekoot. 1994. Mutation detection by denaturing gradient gel electrophoresis (DGGE). Hum. Mutat. 3:83-94.
12. Fukushima, M., K. Kakinuma, H. Hayashi, H. Nagai, K. Ito, and R. Kawaguchi. 2003. Detection and identification of Mycobacterium species isolates by DNA microarray. J. Clin. Microbiol. 41:2605-2615.
13. Guo, Z., R. A. Guilfoyle, A. J. Thiel, R. Wang, and L. M. Smith. 1994. Direct fluorescence analysis of genetic polymorphisms by hybridization with oligonucleotide arrays on glass supports. Nucleic Acids Res. 22:5456-5465.
14. Hacia, J. G., L. C. Brody, M. S. Chee, S. P. A. Fodor, and F. S. Collins. 1996. Detection of heterozygous mutations in BRCA1 using high density oligonucleotide array and two-colour fluorescence analysis. Nat. Genet. 14:441-447.
15. Hacia, J. G., and F. S. Collins. 1999. Mutational analysis using oligonucleotide microarrays. J. Med. Genet. 36:730-736.
16. Hooper, D. C. 2001. Emerging mechanisms of fluoroquinolone resistance. Emerg. Infect. Dis. 7:337-341.
17. Kam, K. M., S. S. Kam, D. T. Cheung, V. W. Tung, W. F. Au, and M. M. Cheung. 2003. Molecular characterization of quinolone-resistant Neisseria gonorrhoeae in Hong Kong. Antimicrob. Agents Chemother. 47:436-439.
18. Knapp, J. S., K. K. Fox, D. L. Trees, and W. L. Whittington. 1997. Fluoroquinolone resistance in Neisseria gonorrhoeae. Emerg, Infect. Dis. 3:33-39.
19. National Committee for Clinical Laboratory Standards. 1993. Method for dilution antimicrobial susceptibility test for bacteria that grow aerobically, 3rd ed. Approved standard M7-A3. National Committee for Clinical Laboratory Standards, Villanova, Pa.
20. Schena, M., D. Shalon, R. Heller, et al. 1996. Parallel human genome analysis: microarray-based expression monitoring of 1000 genes. Proc. Natl. Acad. Sci. USA 93:457-460.
21. Shultz, T. R., J. W. Tapsall, and P. A. White. 2001. Correlation of in vitro susceptibilities to newer quinolones of naturally occurring quinolone-resistant Neisseria gonorrhoeae strains with changes in GyrA and ParC. Antimicrob. Agents Chemother. 45:734-738.
22. Small, J., D. R. Call, F. J. Brockman, T. M. Straub, and D. P. Chandler. 2001. Direct detection of 16S rRNA in soil extracts by using oligonucleotide microarrays. Appl. Environ. Microbiol. 67:4708-4716.
23. Su, X., and I. Lind. 2001. Molecular basis of high-level ciprofloxacin resistance in Neisseria gonorrhoeae strains isolated in Denmark from 1995 to 1998. Antimicrob. Agents Chemother. 45:117-123.
24. Tanaka, M., H. Fukuda, K. Hirai, M. Hosaka, T. Matsumoto, and J. Kumazawa. 1994. Reduced uptake and accumulation of norfloxacin in resistant strains of Neisseria gonorrhoeae isolated in Japan. Genitourin. Med. 70:253-255.
25. Trees, D. L., A. L. Sandul, V. Peto-Mesola, M. R. Aplasca, H. B. Leng, W. L. Whittington, and J. S. Knapp. 1999. Alterations within the quinolone resistance-determining regions of GyrA and ParC of Neisseria gonorrhoeae isolated in the Far East and the United States. Int. J. Antimicrob. Agents 12:325-332.
26. Troesch, A., H. Nguyen, C. G. Miyada, S. Desvarenne, T. R. Gingeras, P. M. Kaplan, P. Cros, and C. Mabilat. 1999. Mycobacterium species identification and rifampin resistance testing with high-density DNA probe arrays. J. Clin. Microbiol. 37:49-55.
27. World Health Organization. 1998. Western Pacific Gonococcal Antimicrobial Surveillance Programme. Resistance in gonococci isolated in the Western Pacific Region to various antimicrobials used in the treatment of gonorrhoea, 1997. Commun. Dis. Intell. 22:288-291.
28. Ye, R. W., T. Wang, L. Bedzyk, and K. M. Croker. 2001. Applications of DNA microarrays in microbial systems. J. Microbiol. Methods 47:257-272.