Cloning and characterisation of the gene encoding HMG-CoA reductase from Taxus media and its functional identification in yeast

Functional Plant Biology

Volumn 31, Issue 1, 2004, Pages 73-81

  Liao, Zhihua ^a   Tan, Qiumin ^a   Chai, Yourong ^a   Zuo, Kaijing ^b   Chen, Min ^c   Gong, Yifu ^b,e   Wang, Peng ^a   Pi, Yan ^a   Tan, Feng ^d   Sun, Xiaofen ^a   Tang, Kexuan ^a,b  

^a FUDAN UNIVERSITY   (China)

^b SHANGHAI JIAO TONG UNIVERSITY   (China)

^c FUDAN UNIVERSITY   (China)

^d SOUTHWEST UNIVERSITY   (China)

^e NINGBO UNIVERSITY   (China)

Author keywords

Cloning; HMGR; Mevalonate biosynthesis; Taxus media; Yeast complementation

Indexed keywords

BIOLOGICAL MEMBRANES; BIOSYNTHESIS; CATALYSIS; CLONING; COENZYMES; GENETIC ENGINEERING;

BIOINFORMATIC ANALYSIS; OPEN READING FRAME (ORF);

YEAST;

ENZYME; GENE EXPRESSION; YEAST;

EMBRYOPHYTA; GYMNOSPERMAE; TAXUS; TAXUS X MEDIA;

EID: 10744232192     PISSN: 14454408     EISSN: None     Source Type: Journal    
DOI: 10.1071/FP03153     Document Type: Article

References (28)

1. Ausubel FM, Brent R, Kingston RE, Moore DD, Seidman JG, Smith JA, Struhl K (1995) (Eds) 'Short protocols in molecular biology (3rd edn).' (John Wiley and Sons, Inc.: New York)
2. Basson ME, Thorsness M, Rine J (1986) Saccharomyces cerevisiae contains two functional genes encoding 3-hydroxy-3-methylglutaryl-coenzyme A reductase. Proceedings of the National Academy of Sciences USA 83, 563-567.
3. Caelles C, Ferrer A, Balcells L, Hegardt FG, Boronat A (1989) Isolation and structural characterization of a cDNA encoding Arabidopsis thaliana 3-hydroxy-3-methylglutaryl coenzyme A reductase. Plant Molecular Biology 13, 627-638.
4. Chye ML, Kush A, Tan CT, Chua NH (1991) Characterization of cDNA and genomic clones encoding 3-hydroxy-3-methylglutaryl-coenzyme A reductase from Hevea brasiliensis. Plant Molecular Biology 16, 567-577.
5. Combet C, Blanchet C, Geourjon C, Deléage G (2000) NPS@: Network Protein Sequence Analysis. Trends in Biochemical Sciences 25, 147-150. doi:10.1016/S0968-0004(99)01540-6
6. Eisenreich W, Menhard B, Hylands PJ, Zenk MH, Bacher A (1996) Studies on the biosynthesis of taxol: the taxane carbon skeleton is not of mevalonoid origin. Proceedings of the National Academy of Sciences USA 93, 6431-6436. doi:10.1073/PNAS.93.13.6431
7. Fernie AR (2003) Metabolome characterization in plant system analysis. Functional Plant Biology 30, 111-120. doi:10.1071/ FP02163
8. Goodman J, Walsh V (Eds) (2001) 'The story of taxol: nature and politics in the pursuit of an anti-cancer drug.' (Cambridge University Press: Cambridge, UK)
9. Istvan ES, Deisenhofer J (2000) The structure of the catalytic portion of human HMG-CoA reductase. Archives of Biochemistry and Biophysics 1529, 9-18. doi:10.1016/S1388-1981(00)00134-7
10. Kaiser C, Michaelis S, Mitchell A (1994) (Eds) 'Methods in yeast genetics.' (Cold Spring Harbor Laboratory Press: Cold Spring Harbor, NY)
11. Kato-Emori S, Higashi K, Hosoya K, Kobayashi T, Ezura H (2001) Cloning and characterization of the gene encoding 3-hydroxy-3-methylglutaryl coenzyme A reductase in melon (Cucumis melo L. reticulatus). Molecular Genetics and Genomics 265, 135-142. doi:10.1007/S004380000401
12. Lansing A, Haertel M, Gordon M, Floss HG (1991) Biosynthetic studies on taxol. Planta Medica 57, 83.
13. Learned RM, Fink GR (1989) 3-Hydroxy-3-methylglutaryl-coenzyme A reductase from Arabidopsis thaliana is structurally distinct from the yeast and animal enzymes. Proceedings of the National Academy of Sciences USA 86, 2779-2783.
14. Maldonado-Mendoza IE, Burnett RJ, Nessler CL (1992) Nucleotide sequence of a cDNA encoding 3-hydroxy-3-methylglutaryl coenzyme A reductase from Catharanthus roseus. Plant Physiology 100, 1613-1614.
15. Maldonado-Mendoza IE, Vincent RM, Nessler CL (1997) Molecular characterization of three differentially expressed members of the Camptotheca acuminata 3-hydroxy-3-methylglutaryl CoA reductase (HMGR) gene family. Plant Molecular Biology 34, 781-790. doi:10.1023/A:1005866813347
16. Murashige T, Skoog F (1962) A revised medium for rapid growth and bioassays with tobacco tissue cultures. Physiologia Plantarum 15, 473-479.
17. Narita JO, Gruissem W (1989) Tomato hydroxymethylglutaryl-CoA reductase is required early in fruit development but not during ripening. The Plant Cell 1, 181-190. doi:10.1105/TPC.1.2.181
18. Nielsen H, Engelbrecht J, Brunak S, Van Heijne G (1997) Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites. Protein Engineering 10, 1-6. doi:10.1093/PROTEIN/10.1.1
19. Palazón J, Cusidó RM, Bonfill M, Morales C, Piñol MT (2003) Inhibition of paclitaxel and baccatin III accumulation by mevinolin and fosmidomycin in suspension cultures of Taxus baccata. Journal of Biotechnology 101, 157-163. doi:10.1016/S0168-1656(02)00318-8
20. Park HS, Denbow CJ, Cramer CL (1992) Structure and nucleotide sequence of tomato HMG2 encoding 3-hydroxy-3-methyl-glutaryl coenzyme A reductase. Plant Molecular Biology 20, 327-331.
21. Ruiz-Albert J, Cerda-Olmedo E, Corrochano LM (2002) Genes for mevalonate biosynthesis in Phycomyces. Molecular Genetics and Genomics 266, 768-777. doi:10.1007/S004380100565
22. Schepmann HG, Pang JH, Matsuda SPT (2001) Cloning and characterization of Ginkgo biloba levopimaradiene synthase which catalyses the first committed step in ginkgolides biosynthesis. Archives of Biochemistry and Biophysics 392, 263-269. doi:10.1006/ABBI.2001.2438
23. Schwede T, Kopp J, Guex N, Peitsch MC (2003) SWISS-MODEL: an automated protein homology-modeling server. Nucleic Acids Research 31, 3381-3385. doi:10.1093/NAR/GKG520
24. Stermer BA, Bianchini GM, Korth KL (1994) Regulation of HMG-CoA reductase activity in plants. Journal of Lipid Research 35, 1133-1140.
25. Wang YD, Yuan YJ, Wu JC (2003) Translocation of isopentenyl pyrophosphate for Taxol biosynthesis in suspension cultures of Taxus chinensis var. mairei. Plant Cell, Tissue and Organ Culture 74, 283-288. doi:10.1023/A:1024019809910
26. Wani MC, Taylor HL, Wall ME, Coggon P, McPhail AT (1971) Plant antitumor agents. The isolation and structure of taxol, a novel antileukemic and antitumor agent from Taxus brevifolia. Journal of the American Chemical Society 93, 2325-2327.
27. Zamir LO, Nedea ME, Belair S, Sauriol F, Mamer O, Jacqmain E, Jean FI, Garneau FX (1992) Biosynthetic building blocks of Taxus canadiensis taxanes. Tetrahedron Letters 33, 5235-5236. doi:10.1016/S0040-4039(00)79141-6
28. Zeng Y, Yang T (2002) RNA isolation from highly viscous samples rich in polyphenols and polysaccharides. Plant Molecular Biology Reporter 20, 417a-417e.