Pharmacology of Novel Heteroaromatic Polycycle Antibacterials

Antimicrobial Agents and Chemotherapy

Volumn 47, Issue 11, 2003, Pages 3448-3457

  Gross, M ^a   Burli R ^a   Jones, P ^a   Garcia, M ^a   Batiste, B ^a   Kaizerman, J ^a   Moser, H ^a   Jiang, V ^a   Hoch, U ^a   Duan, J X ^a   Tanaka, R ^a   Johnson, K W ^a  

^a Genesoft Pharmaceuticals Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; GSQ 10547; GSQ 11203; GSQ 2287; POLYCYCLIC AROMATIC COMPOUND; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBACTERIAL ACTIVITY; ARTICLE; AT RICH SEQUENCE; BACTERIAL GROWTH; CONTROLLED STUDY; DNA BINDING; DNA REPLICATION; DOSE RESPONSE; DRUG DISPOSITION; DRUG DNA BINDING; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENCY; DRUG SAFETY; FEMALE; GENOTOXICITY; LUNG INFECTION; MALE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; MOUSE; NEUTROPENIA; NONHUMAN; PERITONITIS; PRIORITY JOURNAL; PROMOTER REGION; RAT; RNA TRANSCRIPTION; SURVIVAL;

ACETAMIDES; ANIMALS; ANTI-BACTERIAL AGENTS; AREA UNDER CURVE; BACTERIAL INFECTIONS; BEHAVIOR, ANIMAL; CALIBRATION; CATION TRANSPORT PROTEINS; DNA; DOGS; ETHER-A-GO-GO POTASSIUM CHANNELS; FEMALE; HETEROCYCLIC COMPOUNDS; MALE; MICE; MICE, INBRED ICR; MUSCLE, SKELETAL; MUTAGENS; NEUTROPENIA; OXAZOLIDINONES; PERITONITIS; PNEUMONIA, PNEUMOCOCCAL; POTASSIUM CHANNELS; POTASSIUM CHANNELS, VOLTAGE-GATED; PROTEIN BINDING; RATS; RATS, SPRAGUE-DAWLEY; TISSUE DISTRIBUTION; VANCOMYCIN;

EID: 10744228653     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.47.11.3448-3457.2003     Document Type: Article

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