Synthesis, Comparative Photosensitizing Efficacy, Human Serum Albumin (Site II) Binding Ability, and Intracellular Localization Characteristics of Novel Benzobacteriochlorins Derived from vic-Dihydroxybacteriochlorins

Journal of Medicinal Chemistry

Volumn 46, Issue 25, 2003, Pages 5349-5359

  Li, Guolin ^a   Graham, Andrew ^a   Chen, Yihui ^a   Dobhal, Mahabeer P ^a,b   Morgan, Janet ^a   Zheng, Gang ^a   Kozyrev, Andrei ^a   Oseroff, Allan ^a   Dougherty, Thomas J ^a   Pandey, Ravindra K ^a  

^a ROSWELL PARK CANCER INSTITUTE   (United States)

^b UNIVERSITY OF RAJASTHAN   (India)

Author keywords

[No Author keywords available]

Indexed keywords

1,8 DIAZABICYCLO[5.4.0]UNDEC 7 ENE; 2 DICHLOROBENZENE; ACETYLENEDICARBOXYLIC ACID DIMETHYL ESTER; ALKENE DERIVATIVE; BACTERIOCHLORIN; BENZENE DERIVATIVE; BENZOBACTERIOCHLORIN; CHLOROPHYLL A; DIHYDROXYBACTERIOCHLORIN; IMIDE; MESOCHLORIN E6 TRIMETHYL ESTER; MESOPURPURIN 18 N 3,5 BIS(TRIFLUOROMETHYL)BENZYLIMIDE METHYL ESTER; MESOPURPURIN 18 N HEXYLIMIDE METHYL ESTER; METHYL MESOPYROPHEOPHORBIDE A; N SEC BUTYL 1 (2 CHLOROPHENYL) N METHYL 3 ISOQUINOLINECARBOXAMIDE; OSMIUM TETRAOXIDE; PHOTOSENSITIZING AGENT; RHODAMINE 123; SERUM ALBUMIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DIELS ALDER REACTION; DRUG BINDING SITE; DRUG EFFICACY; DRUG PROTEIN BINDING; DRUG SYNTHESIS; HUMAN; IN VITRO STUDY; MITOCHONDRION; MOUSE; NONHUMAN; PHOTOTOXICITY; REACTION ANALYSIS; TUMOR CELL CULTURE;

ANIMALS; BINDING SITES; BINDING, COMPETITIVE; CELL SURVIVAL; CHLOROPHYLL; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MICE; MICE, INBRED C3H; MITOCHONDRIA; NEOPLASM TRANSPLANTATION; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS; PROTEIN BINDING; RADIOLIGAND ASSAY; RECEPTORS, GABA-A; SERUM ALBUMIN; SKIN; SPECTROPHOTOMETRY; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 10744228460     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm030341y     Document Type: Article

References (37)

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